Search results for "imunohistoķīmija"

showing 2 items of 2 documents

Neiroiekaisuma biomarķieru ekspresijas izmaiņas streptozotocīna Alcheimera slimības modelī žurkām ar muscimolu

2016

Alcheimera slimība ir biežākā neirodeģeneratīvā slimība mūsdienu sabiedrībā, ar tendenci slimnieku skaitam ar katru gadu pieaugt. Sarežģītās diagnostikas un neefektīvās farmakoloģiskās terapijas dēļ, šo slimību ir grūti kontrolēt. Pētnieki nodarbojas ar Alcheimera slimības pirms-demences diagnostikas metožu un veiksmīgas farmakoloģiskās terapijas atklāšanu. Balstoties uz iepriekš veiktiem pētījumiem par GABAA agonista muscimola (0,01 un 0,05 mg/kg) spēju samazināt neiroiekaisumu, streptozocīna (STZ) izraisītā Alcheimera slimības modelī žurkām [Mareš P., et al. 2014], [Ding Y., et al. 2015], šajā pētījumā tika apskatīta un analizēta neiroiekaisuma biomarķieru ekspresija post mortem žurku sma…

Iba-1demenceAlcheimera slimībaFarmācijaneiroiekaisumsimunohistoķīmija

researchProduct

Centrālās nervu sistēmas ietekme uz adenohipofīzes adenomu attīstību

2015

Adenohipofīzes adenomas ir labdabīgi intrakraniāli endokrīnie audzēji ar potenciāli augstu prevalenci populācijā. To rašanās rezultātā pacientiem var attīstīties plaša spektra veselības problēmas. Bakalaura darbā veikta adenohipofīzes adenomu šūnu izpēte, analizējot to proliferāciju un saistību ar CNS. Darba gaitā tika konstatētas dažādas CNS cilmes šūnām raksturīgās īpašības adenomu paraugos.

cilmes šūnasadenohipofīzes adenomasBioloģijacentrālā nervu sistēmaimunohistoķīmija

researchProduct

PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
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LSLife Sciences
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