Search results for "induction"

Good clinical response, remission, and predictors of remission in rheumatoid arthritis patients treated with tumor necrosis factor-α blockers: The GI…

2007

OBJECTIVE: To assess the prevalence of good clinical response and remission in rheumatoid arthritis (RA) patients with longstanding disease treated with anti-tumor necrosis factor-alpha (TNF-alpha) drugs at outpatient clinics. METHODS: Retrospective national study of 14 academic tertiary referral rheumatology medical centers. RA patients with a Disease Activity Score (DAS28) > 3.2 were defined as having active disease and could start TNF-alpha blockers. All patients received one TNF-alpha blocker plus methotrexate (10-20 mg/wk). At the third month the patients were categorized as responders or nonresponders, based on improvement of at least 0.25 of the Health Assessment Questionnaire (HAQ).…

Inhibition of small G proteins of the Rho family by statins orClostridium difficiletoxin B enhances cytokine-mediated induction of NO synthase II

2000

In order to investigate the involvement of Ras and/or Rho proteins in the induction of the inducible isoform of nitric oxide synthase (NOS II) we used HMG-CoA reductase inhibitors (statins) and Clostridium difficile toxin B (TcdB) as pharmacological tools. Statins indirectly inhibit small G proteins by preventing their essential farnesylation (Ras) and/or geranylgeranylation (Rho). In contrast, TcdB is a glucosyltransferase and inactivates Rho-proteins directly. Human A549/8- and DLD-1 cells as well as murine 3T3 fibroblasts were preincubated for 18 h with statins (1–100 μM) or TcdB (0.01–10 ng ml−1). Then NOS II expression was induced by cytokines. NOS II mRNA was measured after 4–8 h by R…

Automatic Taxonomy Induction based on Word-embedding of Neural Nets

2018

Taxonomy is a knowledge management tool that presents useful information in a well-ordered structure prevents overloading of information on its access and making the information access qualitative. This article is concerned with automatically extracting asymmetrical hierarchical relations from a large corpus and subsequent taxonomy construction by domain independent and semi-supervised system. The methodology relies on the term’s distributional semantics. The algorithm utilizes the word-embedding generated from the vector space model. The model is trained over a large corpus to generate word-embedding of each word in a corpus. Then, the system finds and extracts the hypernyms by using the g…

Performance Improvement of Grid-Integrated Doubly Fed Induction Generator under Asymmetrical and Symmetrical Faults

2023

The doubly fed induction generator (DFIG)-based wind energy conversion system (WECS) suffers from voltage and frequency fluctuations due to the stochastic nature of wind speed as well as nonlinear loads. Moreover, the high penetration of wind energy into the power grid is a challenge for its smooth operation. Hence, symmetrical faults are most intense, inflicting the stator winding to low voltage, disturbing the low-voltage ride-through (LVRT) functionality of a DFIG. The vector control strategy with proportional–integral (PI) controllers was used to control rotor-side converter (RSC) and grid-side converter (GSC) parameters. During a symmetrical fault, however, a series grid-side converter…

Graves’ disease

2017

Mathematical models and stability analysis of induction motors under sudden changes of load

2013

Ultraviolet A1 radiation induces nitric oxide synthase-2 expression in human skin endothelial cells in the absence of proinflammatory cytokines.

2001

Skin exposure to ultraviolet radiation from sunlight causes erythema and edema formation as well as inflammatory responses. As some of these ultraviolet-induced effects are potentially mediated by nitric oxide synthases, we examined the role of cytokines and ultraviolet A 1 radiation (340–400 nm) on the expression of the nitric oxide synthase-2 in endothelia of normal human skin biopsies during short-term organ culture as well as expression and activity of the nitric oxide synthase-2 in in vitro cell cultures of human dermal endothelial cells. Both, cytokine challenge (interleukin-1β + tumor necrosis factor-α + interferon-γ) but also ultraviolet A 1 exposure (50 J per cm 2 ) in the absence …

Water in stereoselective organocatalytic reactions

2009

In this review, recent advances in asymmetric organocatalytic reactions carried out with variable amounts of water, from substoichiometric to a large excess (reaction medium), are discussed. We also summarize several proposed mechanisms for the different possibilities of the action of water both in the increased activity of the catalyst and in the asymmetric induction. Finally, the application of this catalytic methodology to the enantioselective synthesis of valuable compounds through enamine or iminium catalysis is presented.

An IPMSM torque/weight and torque/moment of inertia ratio optimization

2014

In this paper, a torque/weight and torque/moment of inertia ratio optimization procedure for interior permanent magnet syncronous motors (IPMSMs) is presented. More in detail, a performance comparison between several IPMSM rotor structures has been carried out in order to determine the optimum geometry that can maximize the torque/weight and torque/moment of inertia ratios. A commercial motor, with known electrical and mechanical characteristics, has been taken as reference. Its rotor structure has been modified several times, obtaining different rotor geometries and, therefore, many IPMSM models with different electrical and mechanical characteristics. The finite element method (FEM) analy…