Search results for "infants"

showing 10 items of 260 documents

Next-Generation Sequencing Identifies Potential Actionable Targets in Paediatric Sarcomas

2021

Background: Bone and soft-tissue sarcomas represent 13% of all paediatric malignancies. International contributions to introduce next-generation sequencing (NGS) approaches into clinical application are currently developing. We present the results from the Precision Medicine program for children with sarcomas at a reference centre. Results: Samples of 70 paediatric sarcomas were processed for histopathological analysis, reverse transcriptase polymerase chain reaction (RT-PCR) and next-generation sequencing (NGS) with a consensus gene panel. Pathogenic alterations were reported and, if existing, targeted recommendations were translated to the clinic. Seventy paediatric patients with sarcomas…

0301 basic medicineOncologyCàncer en els infantsmedicine.medical_specialtyprecision medicinetargeted drugslcsh:MedicineMedicine (miscellaneous)Articlepaediatric sarcomasclinical translationDNA sequencinglaw.invention03 medical and health sciences0302 clinical medicinelawInternal medicineGene panelmedicineOssos MalaltiesPolymerase chain reactionPaediatric patientsBiological studiesbusiness.industrylcsh:RHistopathological analysisPrecision medicine030104 developmental biology030220 oncology & carcinogenesisCohortnext-generation sequencingbusinessJournal of Personalized Medicine
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Prenatal Ambient Air Pollution, Placental Mitochondrial DNA Content, and Birth Weight in the INMA (Spain) and ENVIRONAGE (Belgium) Birth Cohorts

2016

The research leading to these results was funded by the Spanish Ministry of Health (FIS-PI11/00610, FIS-PI041436, FIS-PI081151, FIS-PI042018, and FIS-PI09/02311), the European Union (EU) (FP7-ENV-2011 cod 282957 and HEALTH.2010.2.4.5-1), the Instituto de Salud Carlos III (Red INMA G03/176, CB06/02/0041, FIS-FEDER 03/1615, 04/1509, 04/1112, 04/1931, 05/1079, 05/1052, 06/1213, 07/0314, 09/02647, 11/01007, 11/02591, CP11/00178, FIS-PI06/0867, and FIS-PS09/00090), the Conselleria de Sanitat Generalitat Valenciana, the Generalitat de Catalunya-CIRIT (1999SGR 00241), the Obre Social Cajastur, the Universidad de Oviedo, the Department of Health of the Basque Government (2005111093 and 2009111069),…

0301 basic medicinePediatrics:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Birth Weight [Medical Subject Headings]:Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Morphogenesis::Embryonic and Fetal Development::Fetal Development [Medical Subject Headings]Health Toxicology and MutagenesisPlacentaEspañaPhysiology:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Growth Disorders::Fetal Growth Retardation [Medical Subject Headings]ADN mitocondrial010501 environmental sciencesMitochondrion01 natural sciencesFetal DevelopmentBélgicaPregnancyBirth Weightskin and connective tissue diseasesPeso al nacerNews | Science SelectionsMitocondrias:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]:Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria [Medical Subject Headings]2. Zero hunger:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]Air PollutantsAmbient air pollutionAire -- ContaminacióFemenino3. Good healthmedicine.anatomical_structureMaternal ExposureFemaleBirth cohort:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Air Pollution [Medical Subject Headings]Mitochondrial DNAmedicine.medical_specialtyModelos LinealesEmbarazoBirth weightInfants -- DesenvolupamentBiology:Chemicals and Drugs::Inorganic Chemicals::Gases::Nitrogen Oxides::Nitrogen Dioxide [Medical Subject Headings]DNA Mitochondrial:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes Mitochondrial [Medical Subject Headings]03 medical and health sciencesAir pollutantsPlacentaAir PollutionmedicineHumans:Geographicals::Geographic Locations::Europe::Belgium [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Linear Models [Medical Subject Headings]Contaminación del aire0105 earth and related environmental sciencesRetardo del crecimiento fetal:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::DNA::DNA Circular::DNA Mitochondrial [Medical Subject Headings]Genes mitocondrialesPregnancyPublic Health Environmental and Occupational HealthDesarrollo fetalmedicine.disease:Anatomy::Embryonic Structures::Placenta [Medical Subject Headings]030104 developmental biology:Check Tags::Female [Medical Subject Headings]13. Climate actionSpainsense organsDióxido de nitrógeno
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A Genome-Wide Association Study of Attention Function in a Population-Based Sample of Children

2016

BACKGROUND: Attention function filters and selects behaviorally relevant information. This capacity is impaired in some psychiatric disorders and has been proposed as an endophenotype for Attention-Deficit/Hyperactivity Disorder; however, its genetic basis remains largely unknown. This study aimed to identify single nucleotide polymorphism (SNPs) associated with attention function. MATERIALS AND METHODS: The discovery sample included 1655 children (7-12 years) and the replication sample included 546 children (5-8 years). Five attention outcomes were assessed using the computerized Attentional Network Test (ANT): alerting, orienting, executive attention, Hit Reaction time (HRT) and the stand…

0301 basic medicineSocial Scienceslcsh:MedicineGenome-wide association studyBioinformatics0302 clinical medicineHuman geneticsMedicine and Health SciencesMedicinePsychologyAttentionlcsh:ScienceSalut mentalMultidisciplinaryGenètica humanaNeurodegenerative DiseasesGenomicsAlzheimer's diseaseNeurologyResearch ArticleHiperactivitatImaging TechniquesInfants -- DesenvolupamentBrain Structure and FunctionSingle-nucleotide polymorphismNeuroimagingNeuropsychiatric DisordersResearch and Analysis Methods03 medical and health sciencesNeuroimagingDevelopmental NeuroscienceAlzheimer DiseaseMental Health and PsychiatryGenome-Wide Association StudiesGeneticsSNPAllelesbusiness.industrylcsh:RCognitive PsychologyBiology and Life SciencesComputational BiologyHuman GeneticsGenome AnalysisHuman genetics030104 developmental biologyMalaltia d'AlzheimerGenetic LociNeurodevelopmental DisordersEndophenotypeMultiple comparisons problemCognitive ScienceDementiaAdhdlcsh:Qbusiness030217 neurology & neurosurgeryNeuroscience
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Pathways of care for HIV infected children in Beira, Mozambique: pre-post intervention study to assess impact of task shifting

2018

Abstract Background In 2013, Mozambique implemented task-shifting (TS) from clinical officers to maternal and child nurses to improve care for HIV positive children < 5 years old. A retrospective, pre-post intervention study was designed to evaluate effectiveness of a new pathway of care in a sample of Beira District Local Health Facilities (LHFs), the primary, local, community healthcare services. Methods The study was conducted by accessing registries of At Risk Children Clinics (ARCCs) and HIV Health Services. Two time periods, pre- and post-intervention, were compared using a set of endpoints. Variables distribution was explored using descriptive statistics. T-student, Mann Whitney and …

0301 basic medicinemedicine.medical_specialtyReferralHIV InfectionsHIV infected childrenSettore MED/42 - Igiene Generale E ApplicataPost-intervention03 medical and health sciences0302 clinical medicineHIV exposed infants; HIV infected children; Human immunodeficiency virus; Paediatric HIV care and treatment; Pathways of care; Task-shiftingIntervention (counseling)EpidemiologyHealth caremedicineHumansHealth Workforce030212 general & internal medicineHuman immunodeficiency viruReferral and ConsultationMozambiqueRetrospective StudiesDescriptive statisticsbusiness.industryHuman immunodeficiency virusPublic healthlcsh:Public aspects of medicinePaediatric HIV care and treatmentPublic Health Environmental and Occupational HealthInfantHIV exposed infantlcsh:RA1-1270030112 virologyTask-shiftingHIV exposed infantsCD4 Lymphocyte CountChild PreschoolFamily medicineHealth Services ResearchBiostatisticsbusinessDelivery of Health CarePathways of careResearch ArticleBMC Public Health
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Effects of maternal singing during kangaroo care on maternal anxiety, wellbeing, and mother-infant relationship after preterm birth: a mixed methods …

2020

Introduction: Preterm birth may disturb the typical development of the mother– infant relationship, when physical separation and emotional distress in the neonatal intensive care unit may increase maternal anxiety and create challenges for early interaction. This cluster-randomized controlled trial examined the effects of maternal singing during kangaroo care on mothers’ anxiety, wellbeing, and the early mother– infant relationship after preterm birth. Method: In the singing intervention group, a certified music therapist guided the mothers (n = 24) to sing or hum during daily kangaroo care during 33–40 gestational weeks (GW). In the control group, the mothers (n = 12) conducted daily kanga…

030506 rehabilitationNeonatal intensive care unitMother infantmusiikkiterapiaMUSIC-THERAPYvanhempi-lapsisuhdePARENTSEmotional distressMedicineEarly interactionWEIGHT INFANTSPREMATURE-INFANTSmaternal singingearly interactionKangaroo careNEWBORNS05 social sciencesEXPERIENCEShumanities3. Good healthemotional connectionkeskosetennenaikainen synnytysPshychiatric Mental HealthMaternal anxietySinging0305 other medical scienceClinical psychologyNICUMusic therapy515 Psychology050105 experimental psychologypreterm infant03 medical and health sciencesArts and Humanities (miscellaneous)tunteetahdistus0501 psychology and cognitive sciencesEXPOSUREvarhainen vuorovaikutusmaternal anxietybusiness.industryVOICEpreterm birthlaulaminenComplementary and alternative medicineAnthropologyPhysical separationäitiysFATHERSbusinessNordic Journal of Music Therapy
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El teatre actual per a infants al País Valencià: Pluja Teatre (1980-1995)

2014

El teatre actual per a infants al País Valencià: Pluja Teatre (1980-1995) és un estudi que aspira a assolir un doble objectiu, d’una banda, la descripció de l’activitat teatral al País Valencià des del final del franquisme fins a la primera meitat dels anys noranta, tot subratllant la tasca que du a terme aquesta companyia de Gandia (la Safor) durant aquest període. De l’altra, l’establiment d’un esquema d’anàlisi dels espectacles per a infants que, a més de permetre aprofundir en els trets principals de les obres d’aquesta companyia, possibilite una visió al màxim d’exhaustiva de qualsevol espectacle teatral. Tenint en compte aquest doble objectiu, en aquest treball es focalitza tota l’ate…

:LINGÜÍSTICA [UNESCO]teatre per a infantspluja teatreteatre valenciàliteratura per a infants i jovesteatre independentUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRAS::Teoría análisis y crítica literarias::Análisis literarioUNESCO::LINGÜÍSTICAanàlisi espectacular:CIENCIAS DE LAS ARTES Y LAS LETRAS::Teoría análisis y crítica literarias::Análisis literario [UNESCO]
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International BEAT-PCD Consensus Statement for Infection Prevention and Control for Primary Ciliary Dyskinesia in collaboration with ERN-LUNG PCD Cor…

2021

Introduction In primary ciliary dyskinesia (PCD) impaired mucociliary clearance leads to recurrent airway infections and progressive lung destruction, and concern over chronic airway infection and patient-to-patient transmission is considerable. So far, there has been no defined consensus on how to control infection across centres caring for patients with PCD. Within the BEAT-PCD network, COST Action and ERS CRC together with the ERN-Lung PCD core a first initiative has now been taken towards creating such a consensus statement. Methods A multidisciplinary international PCD expert panel was set up to create a consensus statement for infection prevention and control (IP&C) for PCD, covering …

:Otros calificadores::Otros calificadores::/prevención & control [Otros calificadores]Infeccions respiratòries en els infantsPrimary Ciliary DyskinesiaStatement (logic)Respiratory SystemMULTICENTERRECOMMENDATIONS0302 clinical medicineOriginal Research ArticlesPandemicSTENOTROPHOMONAS-MALTOPHILIAInfection control:Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [DISEASES]030212 general & internal medicinePrimary ciliary dyskinesiaMalalties transmissibles - Transmissió:Environmental Health::Health::Environmental Illness::Communicable Diseases::Communicable Disease Control [PUBLIC HEALTH]FOUNDATIONbiologyTransmission (medicine)R:Congenital Hereditary and Neonatal Diseases and Abnormalities::Congenital Abnormalities::Abnormalities Multiple::Ciliopathies::Congenital Hereditary and Neonatal Diseases and Abnormalities::Ciliary Motility Disorders [DISEASES]:afecciones patológicas signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedad crónica [ENFERMEDADES]:salud ambiental::salud::enfermedad ambiental::enfermedades transmisibles::control de enfermedades transmisibles [SALUD PÚBLICA]medicine.anatomical_structureMedicinePatient representativesLife Sciences & BiomedicinePulmonary and Respiratory Medicinemedicine.medical_specialty3610 Medicine & health:enfermedades y anomalías neonatales congénitas y hereditarias::anomalías congénitas::anomalías múltiples::ciliopatías::enfermedades y anomalías neonatales congénitas y hereditarias::trastornos de la motilidad ciliar [ENFERMEDADES]:Other subheadings::Other subheadings::/prevention & control [Other subheadings]03 medical and health sciencesotorhinolaryngologic diseasesmedicineIntensive care medicineScience & TechnologyCYSTIC-FIBROSISLungbusiness.industryPSEUDOMONAS-AERUGINOSAMalalties cròniques - PrevencióCAREEFFICACYmedicine.diseasebiology.organism_classificationrespiratory tract diseases030228 respiratory systemNontuberculous mycobacteria610 Medizin und GesundheitbusinessERJ Open Research
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R. D. G. M. Ad peccatorem Sodomitam

1485

Sign.: a6, b4. - Data aprox., al voltant de 1485 L. gòt. - 30-31 lín. - Min. p. inic. - Filigr.: àguila desplegada

Abús sexual envers els infants Obres anteriors a 1800Abús sexual envers els infants Obres anteriors al 1800DIG-BH
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Abuso Sexual Infantil: una Revisión de los Síntomas Asociados con el Trastorno Por Estrés Postraumático

2011

La incidencia de personas que han sufrido abusos sexuales durante su infancia o adolescencia es elevada. Algunas de estas personas han tenido que convivir durante mucho tiempo con su agresor, algunas veces de forma física y otras en su mente. Ven como su vida se va poco a poco desquebrajando, sufren todo tipo de dolencias físicas, dificultades sexuales y problemas psicológicos. Cuando el abuso sexual infantil ocurre a edades muy tempranas y se ha prolongado a lo largo del tiempo, la relación con el desarrollo de Trastornos de Ansiedad y en concreto del Trastorno Por Estrés Postraumático es más que significativa. El objetivo de la presente revisión teórica es revisar la información reciente …

Abús sexual envers els infants
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Factores inhibidores de la revelación de abuso sexual infantil.

2016

A large number of children sexually abused never reveal their victimization. In some of the cases that do it, the latency of the disclosure is of years or even decades. Al though there are many studies on the factors that influence the revelation of Child Sex Abuse (CSA), in Spain there are no recent publications that encompass and synthesize the currently available scientific evidence about the factors related to the different figures of the victim, the perpetrator and the relationship between them. In this work we revised several studies and meta-studies about the reasons that lead the victims to keep the abuse secret. To the difficulties that generally children present to reveal a secret…

Abús sexual envers els infants
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