Search results for "init"

showing 10 items of 6629 documents

IL-21 Regulates the Differentiation of a Human γδ T Cell Subset Equipped with B Cell Helper Activity

2012

Vγ9Vδ2 T lymphocytes recognize nonpeptidic antigens without presentation by MHC molecules and display pleiotropic features. Here we report that coculture of Vγ9Vδ2 cells with phosphoantigen and IL-21 leads to selective expression of the transcription repressor Bcl-6 and polarization toward a lymphocyte subset displaying features of follicular B-helper T (T(FH)) cells. T(FH) like Vγ9Vδ2 cells have a predominant central memory (CD27(+)CD45RA(-)) phenotype and express ICOS, CD40L and CXCR5. Upon antigen activation, they secrete IL-4, IL-10 and CXCL13, and provide B-cell help for antibody production in vitro. Our findings delineate a subset of human Vγ9Vδ2 lymphocytes, which, upon interaction w…

Anatomy and PhysiologyImmunoglobulin delta-ChainsB CellsCellular differentiationAntibody Affinitylcsh:MedicineAdaptive Immunitychemistry.chemical_compoundWhite Blood CellsSpectrum Analysis TechniquesCell MovementAnimal CellsImmune PhysiologyMedicine and Health SciencesCytotoxic T celllcsh:ScienceImage CytometryB-LymphocytesMultidisciplinarybiologyT CellsCell DifferentiationT-Lymphocytes Helper-InducerFlow CytometryInnate ImmunityDNA-Binding Proteinsmedicine.anatomical_structureIL-21 differentiation Vγ9Vδ2 T lymphocytesSpectrophotometryCD4 AntigensProto-Oncogene Proteins c-bcl-6CytokinesMedicineCytophotometryChemokinesCellular TypesResearch ArticleCD4 antigenImmunoglobulin gamma-ChainsImmune CellsImmunologyMajor histocompatibility complexResearch and Analysis MethodsAntigenmedicineHumansCXCL13Antibody-Producing CellsBiologyB cellCell ProliferationSettore MED/04 - Patologia GeneraleCD40Blood CellsInterleukinsFluorimetrylcsh:RImmunityBiology and Life SciencesCell BiologyMolecular biologyRetractionchemistryGene Expression RegulationHumoral Immunitybiology.proteinClinical Immunologylcsh:QDevelopmental BiologyPloS one
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Ab initio quasi-relativistic calculations on angular momentum and magnetic couplings of molecular electronic states.

2002

Abstract We formulate an ab initio method of quasirelativistic calculations on angular momentum and magnetic transition matrix elements between adiabatic electronic states of molecules. Our approach is based on the construction of a state-selective effective Hamiltonian and transition density matrices by means of the multireference many-body perturbation theory. Pilot applications to the evaluation of B 0 + u → B ″1 u predissociation matrix elements in I 2 and interactions in the B 0 + u ∼ B 1 u complex of Te 2 are reported.

Angular momentumChemistryAb initioGeneral Physics and AstronomyElectronic structureDiatomic moleculesymbols.namesakeMatrix (mathematics)Ab initio quantum chemistry methodssymbolsPhysical and Theoretical ChemistryAtomic physicsHamiltonian (quantum mechanics)Adiabatic process
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The Ã 1Au state and the T2 potential surface of acetylene: Implications for triplet perturbations in the fluorescence spectra of the à state

1996

The cis–trans isomerization reaction on the T2 surface of acetylene and the lowest excited singlet state of acetylene, A 1Au, are investigated by ab initio electronic structure theory. We report optimized geometries, dipole moments, and harmonic vibrational frequencies of stationary points and adiabatic energy differences between them using basis sets as large as triple‐ζ plus double polarization with higher angular momentum functions, TZ(2df,2pd), and theoretical methods up to coupled‐cluster singles and doubles with a perturbative triples correction [CCSD(T)] and the equation‐of‐motion coupled‐cluster method (EOM‐CCSD). Our theoretical predictions should aid the interpretation of observat…

Angular momentumZeeman effectChemistryAb initioGeneral Physics and AstronomyElectronic structureQuantum chemistryPotential energyDipolesymbols.namesakechemistry.chemical_compoundAcetylenePhysics::Atomic and Molecular ClusterssymbolsPhysics::Chemical PhysicsPhysical and Theoretical ChemistryAtomic physicsThe Journal of Chemical Physics
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Local Berry curvature signatures in dichroic angle-resolved photoelectron spectroscopy from two-dimensional materials

2020

Orbital polarization and Berry curvature signatures are mapped out by circular dichroism in angle-resolved photoemission.

Angular momentumtopologyAb initioPhysics::OpticsPosition and momentum spaceAngle-resolved photoemission spectroscopy02 engineering and technologyDichroic glass01 natural sciencesSettore FIS/03 - Fisica Della MateriaCondensed Matter::Materials ScienceQuantum mechanicsCondensed Matter::Superconductivity0103 physical sciences010306 general physicsResearch ArticlesPhysicsMultidisciplinaryPhysicsSciAdv r-articles021001 nanoscience & nanotechnologyARPESCondensed Matter PhysicsDensity functional theoryCondensed Matter::Strongly Correlated ElectronsBerry connection and curvatureMathematics::Differential Geometry0210 nano-technologyGround stateResearch Article
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Toxicity assessment and biodegradation potential of water-soluble sludge containing 2,4,6-trinitrotoluen

2013

The water-soluble phase of trinitrotoluene-containing sludge (SLP) was characterized with regard to trinitrotoluene (TNT) concentration, ecotoxicity, and a model biodegradation experiment as evaluation criteria for further development of appropriate treatment technologies. SLP contained 67.8 mg TNT/l. The results of germination and root-elongation tests indicated that SLP had a species-specific phytotoxic effect. The results of a 21 day degradation experiment demonstrated TNT conversion to 4-amino-2,6-DNT and 2-amino-4,6-DNT, with a simultaneous reduction in the total concentration of nitroaromatics. Addition of inoculum stimulated the TNT degradation process. The presence of the sludge sol…

Aniline CompoundsEnvironmental EngineeringSewagebiodegradation; enzyme activity; indigenous microorganisms; phytotoxicity; solubility; TNTChemistryGerminationBiodegradationEcotoxicologymusculoskeletal systemPlant RootsBiodegradation EnvironmentalMicrobial population biologyGerminationEnvironmental chemistryVattenbehandlingToxicity TestsToxicityWater TreatmentTrinitrotolueneDegradation (geology)Water treatmentEcotoxicityTrinitrotolueneWater Science and Technology
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Scope and Limitations of Baird's Theory on Triplet State Aromaticity: Application to the Tuning of Singlet–Triplet Energy Gaps in Fulvenes

2007

Utilizing Baird's theory on triplet state aromaticity, we show that the singlet-triplet energy gaps (DeltaE(ST)) of pentafulvenes are easily varied through substitution by as much as 36 kcal mol(-1). This exploits the fact that fulvenes act as aromatic chameleons in which the dipoles reverse on going from the singlet ground state (S(0)) to the lowest pipi* triplet state (T1); thus, their electron distributions are adapted so as to achieve some aromaticity in both states. The results are based on quantum chemical calculations with the OLYP density functional theory method and the CASPT2 ab initio method, as well as spectroscopic determination of DeltaE(ST) by triplet sensitization. The findi…

Aniline CompoundsMolecular StructureOrganic ChemistryTemperatureAb initioAromaticityCyclopentanesGeneral ChemistryElectronAlkenesCarbon DioxideHydrogen-Ion ConcentrationHydrocarbons AromaticCatalysischemistry.chemical_compoundchemistryAb initio quantum chemistry methodsChemical physicsComputational chemistryMicroscopy Electron ScanningDensity functional theorySinglet statePhysics::Chemical PhysicsTriplet stateFulveneChemistry - A European Journal
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Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin

2015

Dodecaborate anions of the type B12X12(2-) and B12X11Y(2-) (X=H, Cl, Br, I and Y=OH, SH, NH3(+), NR3(+)) form strong (K(a) up to 10(6) L mol(-1), for B12Br12(2-)) inclusion complexes with γ-cyclodextrin (γ-CD). The micromolar affinities reached are the highest known for this native CD. The complexation exhibits highly negative enthalpies (up to -25 kcal mol(-1)) and entropies (TΔS up to -18.4 kcal mol(-1), both for B12I12(2-)), which position these guests at the bottom end of the well-known enthalpy-entropy correlation for CDs. The high driving force can be traced back to a chaotropic effect, according to which chaotropic anions have an intrinsic affinity to hydrophobic cavities in aqueous …

AnionsBoron CompoundsModels MolecularHofmeister seriesInorganic chemistrySupramolecular chemistrysyklodekstriinithost–guest complexes010402 general chemistry01 natural sciencessupramolecular chemistryCatalysissupramolekulaarinen kemiaMoleculeBinding siteta116Binding SitescyclodextrinsAqueous solutionMolecular Structure010405 organic chemistryChemistryDodecaborateWaterBorclusterGeneral MedicineGeneral ChemistryAffinitiesCommunicationsboron clusters0104 chemical sciencesCrystallographyChaotropic agentThermodynamicsgamma-CyclodextrinsHofmeister seriesAngewandte Chemie International Edition
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"Identification of mixed bromidochloridotellurate anions in disordered crystal structures of (bdmim)2[TeX2Y4] (X, Y = Br, Cl; bdmim = 1-butyl-2,3-dim…

2013

Abstract The discrete mixed [TeBrxCl6−x]2− anions in their disordered crystal structures have been identified by using the phases prepared by the reaction of 1-butyl-2,3-dimethylimidazolium halogenides (bdmim)X with tellurium tetrahalogenides TeX4 (X = Cl, Br) as examples. Homoleptic (bdmim)2[TeX6] [X = Cl (1), Br (2)] and mixed (bdmim)2[TeBr2Cl4] (3), and (bdmim)2[TeBr4Cl2] (4) are formed depending on the choice of the reagents, and their crystal structures have been determined by single-crystal X-ray diffraction. The coordination environments of tellurium in all hexahalogenidotellurates are almost octahedral. Because of the crystallographic disorder, the mixed [TeBr2Cl4]2− and [TeBr4Cl2]2…

AnionsBromidesModels MolecularMagnetic Resonance SpectroscopyAb initiochemistry.chemical_elementCrystal structureCrystallography X-RaySpectrum Analysis RamanAnalytical Chemistrysymbols.namesakechemistry.chemical_compoundChloridesX-Ray DiffractionHomolepticInstrumentationta116SpectroscopyMolecular StructureChemistryImidazolesAtomic and Molecular Physics and OpticsCrystallographyOctahedronsymbolsTellurium tetrachlorideQuantum TheoryTelluriumRaman spectroscopyTelluriumPowder diffractionSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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Island Homoaromaticity in the W-Shaped 2,4-Diphospha-3-arsapentadienide Anion and Related Compounds - Theoretical and Experimental Investigations

2012

A series of anions with general formula (R2C=P)2Pn– (Pn = N, P, As, Sb; R = H, Me, CF3, SiH3, SiMe3, SiF3) was investigated theoretically at the DFT (RI-BP86/TZVP) and RI-MP2/TZVP levels of approximation. Significantly sharpened central PPnP bond angles were predicted for the species with π-acceptor R substituents. The corresponding bond angle values decrease in the order Pn = N >> P > As > Sb. This finding is in agreement with the previously published structural data for [(Me3Si)2C=P]2P–. An island homoaromaticity was proposed as a suitable explanation for the observed effect. In more detail, it consists of shifting negative charge to the electron-withdrawing terminal groups with formation…

AnionsHomoaromaticity010405 organic chemistryChemistryCharge (physics)010402 general chemistry01 natural sciencesHomoaromaticity0104 chemical sciencesIonInorganic ChemistryCrystallographyDensity functional calculationsMolecular geometryComputational chemistryAb initio quantum chemistry methodsMolecular orbitalsMoleculeMoietyMolecular orbitalAb initio calculations
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Dynamic magnetic materials based on the cationic coordination polymer [Cu(btix)2]n(2n+) [btix = 1,4-bis(triazol-1-ylmethyl)benzene]: tuning the struc…

2012

A three-dimensional coordination polymer, [Cu(btix)(2)(BF(4))(2)](n) [btix = 1,4-bis(triazol-1-ylmethyl)benzene], with antiferromagnetic interactions occurring via the organic ligand, has been prepared and characterized. It has been shown to permit the exchange of anionic species in the crystalline network with modification of the magnetic properties. Coordinated BF(4)(-) can be reversibly exchanged by different anions with (NO(3)(-) and Cl(-)) or without (PF(6)(-) and ClO(4)(-)) dynamic response of the organic ligand, which acts as the only linker between the metal centers. Interestingly, an irreversible exchange occurs with N(3)(-) anions to generate a new coordination polymer, [Cu(btix)(…

AnionsModels MolecularIon exchangeMolecular StructureLigandCoordination polymerPolymersInorganic chemistryCationic polymerizationAb initioCrystallography X-RayMagnetic susceptibilitylaw.inventionInorganic Chemistrychemistry.chemical_compoundCrystallographyMagnetic FieldschemistrylawCationsOrganometallic CompoundsAntiferromagnetismPhysical and Theoretical ChemistryElectron paramagnetic resonanceCopperInorganic chemistry
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