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Sievietes militārajā dienestā: Dienējošu sieviešu pieredze vīriešu dominējošā vidē
2021
Militārā joma vēsturiski un sociāli tiek definēta kā tradicionāli vīrišķīga – tā ir, iespējams, viena no arhetipiski vīrišķīgākajām sociālajām struktūrām Rietumu sabiedrībā (Segal 1995). Taču militārajā dienestā un karadarbībā tik un tā sastopamas arī sievietes. Šajā bakalaura darbā pētīta 23 sieviešu pieredze, kuras visas dienē vai dienējušas Kanādas Bruņotajos spēkos (KBS) pēdējo četrdesmit gadu laikā. Šo sieviešu pieredze apkopota daļēji strukturētās intervijās, kas veiktas gan klātienē, gan rakstiskā formātā. Izmantojot Pjēra Burdjē teoriju par maskulīno dominanci un Reivinas Konelas koncepciju par maskulīno hegemoniju, darbā esmu pētījusi, kā sievietes pieredz militāro vidi caur dzimtē…
Comparison of hemodynamic and structural indices of ascending thoracic aortic aneurysm as predicted by 2-way FSI, CFD rigid wall simulation and patie…
2018
Patient-specific computational modeling is increasingly being used to predict structural and hemodynamic parameters, especially when current clinical tools are not accessible. Indeed, pathophysiology of ascending thoracic aortic aneurysm (ATAA) has been simulated to quantify the risk of complications by novel prognostic parameters and thus to improve the clinical decision-making process related to the intervention of ATAAs. In this study, the relevance of aneurysmal wall elasticity in determining parameters of clinical importance, such as the wall shear stress (WSS), is discussed together with the significance of applying realistic boundary conditions to consider the aortic stretch and twis…
Transcatheter Heart Valve Implantation in Bicuspid Patients with Self-Expanding Device
2021
Bicuspid aortic valve (BAV) patients are conventionally not treated by transcathether aortic valve implantation (TAVI) because of anatomic constraint with unfavorable outcome. Patient-specific numerical simulation of TAVI in BAV may predict important clinical insights to assess the conformability of the transcathether heart valves (THV) implanted on the aortic root of members of this challenging patient population. We aimed to develop a computational approach and virtually simulate TAVI in a group of n.6 stenotic BAV patients using the self-expanding Evolut Pro THV. Specifically, the structural mechanics were evaluated by a finite-element model to estimate the deformed THV configuration in …
On the severity of aortic stenosis in ascending aortic aneurysm: A computational tool to examine ventricular-arterial interaction and aortic wall str…
2020
Abstract An ascending thoracic aortic aneurysm (ATAA) is a life-threatening cardiovascular consequence of vessel dilatation that portends adverse events and death. From a clinical perspective, ATAA should not be treated as an isolated disease, and surgery is often carried out in the presence of AS, aortic insufficiency or a calcified valve leaflet. Aortic stenosis (AS) is common in ATAAs and leads to both vessel rigidity and left ventricular (LV) impairment. In this study, lumped-parameter modeling and computational analysis were used to assess the change in the wall shear stress (WSS) and intramural wall stress of patient-specific ATAA models with different degrees of AS (i.e., mild to sev…
Constitutive modeling of ascending thoracic aortic aneurysms using microstructural parameters.
2016
Ascending thoracic aortic aneurysm (ATAA) has been associated with diminished biomechanical strength and disruption in the collagen fiber microarchitecture. Additionally, the congenital bicuspid aortic valve (BAV) leads to a distinct extracellular matrix structure that may be related to ATAA development at an earlier age than degenerative aneurysms arising in patients with the morphological normal tricuspid aortic valve (TAV). The purpose of this study was to model the fiber-reinforced mechanical response of ATAA specimens from patients with either BAV or TAV. This was achieved by combining image-analysis derived parameters of collagen fiber dispersion and alignment with tensile testing dat…
Real-life assessment of chronic rhinosinusitis patients using mobile technology: the mySinusitisCoach project by EUFOREA
2020
Abstract Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with a substantial personal and socioeconomic burden. Monitoring of patient‐reported outcomes by mobile technology offers the possibility to better understand real‐life burden of CRS. Methods This study reports on the cross‐sectional evaluation of data of 626 users of mySinusitisCoach (mSC), a mobile application for CRS patients. Patient characteristics of mSC users were analysed as well as the level of disease control based on VAS global rhinosinusitis symptom score and adapted EPOS criteria. Results The mSC cohort represents a heterogeneous group of CRS patients with a diverse pattern of major sy…
Accumulation of apoE-enriched triglyceride-rich lipoproteins in patients with coronary artery disease.
2005
Triglycerides (TGs) are vehicled by multiple particles with different abilities to promote atherosclerosis. Among plasma TG-rich lipoproteins (TRLs), subspecies may or may not contain apolipoprotein E (apoE) molecules: in this study, we evaluated the relative contribution of apoE-rich and apoE-poor TRLs to coronary atherosclerosis. We selected a group of males with premature coronary artery disease (CAD) without any of the classical nonlipid risk factors and/or high plasma lipid levels and evaluated the plasma concentration of TRL subspecies in comparison with healthy controls. Patients with CAD and controls had total cholesterol and TG levels within the normal range (despite slightly, even…
Mappings of finite distortion : size of the branch set
2018
Abstract We study the branch set of a mapping between subsets of ℝ n {\mathbb{R}^{n}} , i.e., the set where a given mapping is not defining a local homeomorphism. We construct several sharp examples showing that the branch set or its image can have positive measure.
Closed form coefficients in the Symmetric Boundary Element Approach
2006
Abstract In the area of the structural analysis, the problems connected to the use of the symmetric Galerkin Boundary Element Method (SGBEM) must be investigated especially in the mathematical and computational difficulties that are present in computing the solving system coefficients. Indeed, any coefficient is made by double integrals including often fundamental solutions having a high degree of singularity. Therefore, the related computation proves to be difficult in the solution. This paper suggests a simple computation technique of the coefficients obtained in closed form. Using a particular matrix, called ‘progenitor’ matrix [Panzeca T, Cucco F, Terravecchia S. Symmetric boundary elem…
The Liouville theorem and linear operators satisfying the maximum principle
2020
A result by Courr\`ege says that linear translation invariant operators satisfy the maximum principle if and only if they are of the form $\mathcal{L}=\mathcal{L}^{\sigma,b}+\mathcal{L}^\mu$ where $$ \mathcal{L}^{\sigma,b}[u](x)=\text{tr}(\sigma \sigma^{\texttt{T}} D^2u(x))+b\cdot Du(x) $$ and $$ \mathcal{L}^\mu[u](x)=\int \big(u(x+z)-u-z\cdot Du(x) \mathbf{1}_{|z| \leq 1}\big) \,\mathrm{d} \mu(z). $$ This class of operators coincides with the infinitesimal generators of L\'evy processes in probability theory. In this paper we give a complete characterization of the translation invariant operators of this form that satisfy the Liouville theorem: Bounded solutions $u$ of $\mathcal{L}[u]=0$ i…