Search results for "inn"
showing 10 items of 7124 documents
Editors' note
2015
The book, aimed to give a point of view, collects both the answer given by the students and the theoretical thoughts of scientific directors, professors and tutors who have guided the students during the fifth edition of the OC Open City International Summer School of Piacenza: "Architecture for the Creative City".
La nuova architettura
2019
La Nuova Architettura, titolo dato a questo Seminario, diviene testimonianza dei nuovi rapporti che si vengono ad instaurare fra l’innovazione di stile e di cultura con la città storica, con l’ambiente e i suoi fruitori, attraverso interventi di valorizzazione, di restauro, di paesaggio urbano e verde urbano, d’inclusività sociale, di temporaneità.
Architettura in terra
2013
As a new way of approaching the utilization of the resources of this planet earth, the Author proposes baked earth as a natural, ecological and widely available building material, accessible everywhere and to everybody; starting from the Manifesto for the Right to Build with Baked Earth, the Author cites several examples of contemporary architecture built from this material.
El Palacio de la Aljafería de Zaragoza se convierte en fortaleza
2013
Gracias al trabajo de Alicia Cámara (1989) sobre las fortalezas en época de Felipe II, hemos querido destacar la adaptación a fortaleza que sufrió el Palacio de la Aljafería de Zaragoza y que supuso la modificación de un edificio preexistente adecuada a las exigencias de la época, y que se enmarca perfectamente en la temática de este número de la revista Infolio.
A.P.E.R.: Un progetto di ricerca per l’area mediterranea.
2013
Il Mediterraneo è un'area di contaminazione, come un affresco di mille sfumature e colori. L'importazione di molti elementi provenienti da tutto il mondo ha fatto in modo che il Mediterraneo si evolvesse nella sua dimensione attuale, dove le diverse componenti sono diventate gradualmente elementi costitutivi della vita dei suoi abitanti in vari settori, dal paesaggio, all'architettura, all'arte, alla cucina. Luogo sovrano in cui persiste la consapevolezza che le differenze rappresentano una ricchezza, è stato, è e sarà centro di incontri e conflitti, di fusione e separazione, di convivenza armoniosa e continua diffidenza. E' impensabile volere cancellare le tradizioni di ogni popolo, e non …
Inner areas’ cultural, architectural and landscape heritage: study, enhancement and fruition. Potential driver for sustainable territorial developmen…
2022
The processes of gradual abandonment of inner areas, that have been triggered since the second half of the 20th century, generated problems that have been the subject of a wide-ranging scientific and multidisciplinary debate aimed at developing focused political and planning strategies. In 2013 at national level the SNAI, Italian National Strategy for Inner Areas, and later specific actions activated by the Territorial Cohesion Agency, was founded to aim the reactivation of areas defined as “remote with the intention of mitigating territorial marginalization. This article introduces an international and interdisciplinary Seminar based to discuss some concrete experiences. The debate was att…
Granulocyte functions are independent of arginine availability.
2014
Abstract Arginine depletion via myeloid cell arginase is critically involved in suppression of the adaptive immune system during cancer or chronic inflammation. On the other hand, arginine depletion is being developed as a novel anti-tumor metabolic strategy to deprive arginine-auxotrophic cancer cells of this amino acid. In human immune cells, arginase is mainly expressed constitutively in PMNs. We therefore purified human primary PMNs from healthy donors and analyzed PMN function as the main innate effector cell and arginase producer in the context of arginine deficiency. We demonstrate that human PMN viability, activation-induced IL-8 synthesis, chemotaxis, phagocytosis, generation of RO…
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
2020
The effect of the polyanionic polymer of inorganic polyphosphate (polyP) involved in innate immunity on the binding of the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein to the cellular ACE2 receptor was studied. The RBD surface comprises a basic amino acid stretch of four arginine residues which interact with the physiological polyP (polyP40) and polyP3. Subsequently, the interaction of RBD with ACE2 is sensitively inhibited. After the chemical modification of arginine, an increased inhibition by polyP, at a 1 : 1 molar ratio (polyP : RBP), is measured already at 0.1 μg mL−1. Heparin was ineffective. The results suggest a potential therapeutic benefit of polyP against SARS-C…
Lectotypification of Arnica montana L. (Asteraceae)
2021
A lectotype for Arnica montana L. (Asteraceae) is designated from Linnaeus’ original material preserved in the UPS-BURSER herbarium.
Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet.
2001
Background—On the basis of our concept that atherosclerosis has an immunopathological background, we tested whether activation of the innate immune system influences its progression.Methods and Results—Hypercholesterolemic (0.5% wt/wt diet) rabbits received either repeated intravenous injections of endotoxin (Escherichia colilipopolysaccharide 1.25 to 2.5 μg, once per week) or a self-limiting cutaneousStaphylococcus aureusinfection with or without a quinolone antibiotic. Measured laboratory parameters, including LDL and HDL cholesterols, were similar in the different groups of hypercholesterolemic animals. All endotoxin-treated animals developed transient episodes of fever after endotoxin a…