Search results for "inner"

showing 10 items of 384 documents

Peptides Derived from the Transmembrane Domain of Bcl-2 Proteins as Potential Mitochondrial Priming Tools

2014

The Bcl-2 family of proteins is crucial for apoptosis regulation. Members of this family insert through a specific C-terminal anchoring trans membrane domain (TMD) in the mitochondrial outer membrane where they hierarchically interact to determine cell fate. While the mitochondrial membrane has been proposed to actively participate in these protein protein interactions, the influence of the TMD in the membrane-mediated interaction is poorly understood. Synthetic peptides (TMD-pepts) corresponding to the putative TMD of antiapoptotic (Bcl-2, Bcl-xL, Bcl-w, and Mcl-1) and pro-apoptotic (Bax, Bak) members were synthesized and characterized. TMD-pepts bound more efficiently to mitochondria-like…

Protein ConformationMolecular Sequence DataCell fate determinationBiochemistryHumansCell LineageAmino Acid SequenceInner mitochondrial membranebiologyChemistryCircular DichroismCytochrome cGeneral MedicineMolecular biologyMitochondriaCell biologystomatognathic diseasesTransmembrane domainMembraneProto-Oncogene Proteins c-bcl-2Cell cultureApoptosisbiology.proteinMolecular MedicinePeptidesBacterial outer membranehuman activitiesHeLa Cells
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Immuno-electron microscopic localization of the alpha(1) and beta(1)-subunits of soluble guanylyl cyclase in the guinea pig organ of corti.

2000

Guanylyl cyclases (GC) catalyze the formation of the intracellular signal molecule cyclic GMP from GTP. For some years it has been known that the heme-containing soluble guanylyl cyclase (sGC) is stimulated by NO and NO-containing compounds. The sGC enzyme consists of two subunits (alpha(1) and beta(1)). In the present study, the alpha(1) and beta(1)-subunits were identified in the guinea pig cochlea at the electron microscopic level using a post-embedding immuno-labeling procedure. Ultrathin sections of LR White embedded specimens were incubated with various concentrations of two rabbit polyclonal antibodies to the alpha(1)- and beta(1)-subunit, respectively. The immunoreactivity was visua…

Protein subunitImmunocytochemistryGuinea PigsAntibodiesmedicineAnimalsMicroscopy ImmunoelectronMolecular BiologyHair Cells Auditory InnerbiologyTissue EmbeddingGeneral NeuroscienceMolecular biologyPrimary and secondary antibodiesHair Cells Auditory Outermedicine.anatomical_structureBiochemistrySolubilityOrgan of CortiCytoplasmGuanylate Cyclasebiology.proteinDeiters cellssense organsNeurology (clinical)Hair cellNitric Oxide SynthaseSoluble guanylyl cyclaseDevelopmental BiologySignal TransductionBrain research
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Partial inner product spaces: Some categorical aspects

2012

We make explicit in terms of categories a number of statements from the theory of partial inner product spaces (PIP spaces) and operators on them. In particular, we construct sheaves and cosheaves of operators on certain PIP spaces of practical interest.

Pure mathematicsArticle SubjectApplied MathematicsPhysicsQC1-999categoriesGeneral Physics and AstronomyFOS: Physical sciencesMathematical Physics (math-ph)QC20Inner product spaceSettore MAT/05 - Analisi MatematicaMathematics::Category Theory46Cxx 18BxxPip-spaceConstruct (philosophy)Categorical variableMathematical PhysicsMathematics
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Notions of Dirichlet problem for functions of least gradient in metric measure spaces

2019

We study two notions of Dirichlet problem associated with BV energy minimizers (also called functions of least gradient) in bounded domains in metric measure spaces whose measure is doubling and supports a (1, 1)-Poincaré inequality. Since one of the two notions is not amenable to the direct method of the calculus of variations, we construct, based on an approach of Juutinen and Mazón-Rossi–De León, solutions by considering the Dirichlet problem for p-harmonic functions, p>1, and letting p→1. Tools developed and used in this paper include the inner perimeter measure of a domain. Peer reviewed

Pure mathematicsGeneral MathematicsPoincaré inequalitycodimension 1 Hausdorff measure01 natural sciencesMeasure (mathematics)symbols.namesakeMathematics - Analysis of PDEsMathematics - Metric GeometryFOS: Mathematicsinner trace0101 mathematicsleast gradientMathematicsDirichlet problemDirichlet problemp-harmonicDirect method010102 general mathematicsA domainMetric Geometry (math.MG)perimeterfunction of bounded variationmetric measure spacePoincaré inequalityBounded functionMetric (mathematics)symbolsAnalysis of PDEs (math.AP)
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Fixpunktmengen von halbeinfachen Automorphismen in halbeinfachen Lie-Algebren

1976

Let g be a semisimple Lie algebra over an algebraically closed field of characteristic 0. The set of fixed points of a semisimple inner automorphism of g is a regular reductive subalgebra of maximal rank [1], so it is defined by a subsystem of the root system Φ of g relative to a suitable Cartan subalgebra. The main theorem of the article characterizes the corresponding subsystems of Φ. The second part of the article shows how to compute the fixed point algebras of semisimple outer automorphisms of g. A complete list of all fixed point algebras is then easily obtainable. The results are applied to bounded symmetric domains. References

Pure mathematicsGeneral MathematicsSubalgebraCartan subalgebra510 MathematikFixed pointAutomorphism510 MathematicsInner automorphismMathematics::Quantum AlgebraBounded functionAlgebraically closed fieldMathematics::Representation TheorySemisimple Lie algebraMathematics
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Inner functions and local shape of orthonormal wavelets

2011

Abstract Conditions characterizing all orthonormal wavelets of L 2 ( R ) are given in terms of suitable orthonormal bases (ONBs) related with the translation and dilation operators. A particular choice of the ONBs, the so-called Haar bases, leads to new methods for constructing orthonormal wavelets from certain families of Hardy functions. Inner functions and the corresponding backward shift invariant subspaces articulate the structure of these families. The new algorithms focus on the local shape of the wavelet.

Pure mathematicsHardy spacesApplied MathematicsMathematical analysisWavelet transformHardy spaceLinear subspacesymbols.namesakeGeneralized Fourier seriesWaveletOrthonormal waveletssymbolsOrthonormal basisInvariant (mathematics)OrthonormalityInner functionsMathematicsApplied and Computational Harmonic Analysis
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Sharp estimate on the inner distance in planar domains

2020

We show that the inner distance inside a bounded planar domain is at most the one-dimensional Hausdorff measure of the boundary of the domain. We prove this sharp result by establishing an improved Painlev\'e length estimate for connected sets and by using the metric removability of totally disconnected sets, proven by Kalmykov, Kovalev, and Rajala. We also give a totally disconnected example showing that for general sets the Painlev\'e length bound $\kappa(E) \le\pi \mathcal{H}^1(E)$ is sharp.

Pure mathematicsMathematics - Complex VariablesGeneral MathematicsBoundary (topology)accessible pointsMetric Geometry (math.MG)31A15Domain (mathematical analysis)inner distancePlanarMathematics - Metric GeometryPrimary 28A75. Secondary 31A15Bounded functionTotally disconnected spaceMetric (mathematics)FOS: Mathematics28A75Hausdorff measureComplex Variables (math.CV)Painlevé lengthMathematics
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Banach partial *-algebras: an overview

2019

A Banach partial $*$-algebra is a locally convex partial $*$-algebra whose total space is a Banach space. A Banach partial $*$-algebra is said to be of type (B) if it possesses a generating family of multiplier spaces that are also Banach spaces. We describe the basic properties of these objects and display a number of examples, namely, $L^p$-like function spaces and spaces of operators on Hilbert scales or lattices. Finally we analyze the important cases of Banach quasi $*$-algebras and $CQ^*$-algebras.

Pure mathematicsMathematics::Functional AnalysisAlgebra and Number Theorypartial inner product spacesPartial *-algebra Banach partial *-algebra CQ*-algebra partial inner product space operators on Hilbert scale.Partial algebraPartial *-algebraspartial $*$-algebraCQ*-algebraspartial inner product spaceSettore MAT/05 - Analisi Matematica$CQ^*$-algebraBanach partial *-algebrasoperators on Hilbert scaleBanach partial $*$-algebra46J1008A55Analysis47L60Mathematics
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PIP-Space Valued Reproducing Pairs of Measurable Functions

2019

We analyze the notion of reproducing pairs of weakly measurable functions, a generalization of continuous frames. The aim is to represent elements of an abstract space Y as superpositions of weakly measurable functions belonging to a space Z : = Z ( X , μ ), where ( X , μ ) is a measure space. Three cases are envisaged, with increasing generality: (i) Y and Z are both Hilbert spaces; (ii) Y is a Hilbert space, but Z is a pip-space; (iii) Y and Z are both pip-spaces. It is shown, in particular, that the requirement that a pair of measurable functions be reproducing strongly constrains the structure of the initial space Y. Examples are presented for each case.

Pure mathematicspartial inner product spacesMeasurable functionLogicGeneralizationreproducing pairs; continuous frames; upper and lower semi-frames; partial inner product spacesStructure (category theory)upper and lower semi-framecontinuous frameAbstract spaceSpace (mathematics)01 natural sciencesMeasure (mathematics)symbols.namesakeSettore MAT/05 - Analisi Matematica0103 physical sciences0101 mathematics010306 general physicsreproducing pairMathematical PhysicsMathematicscontinuous framesAlgebra and Number Theorylcsh:Mathematics010102 general mathematicsHilbert spaceupper and lower semi-frameslcsh:QA1-939reproducing pairssymbolsGeometry and TopologyAnalysis
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Una filosofia politica sulle orme di Wittgenstein? Il contributo di Quentin Skinner

2012

Q. Skinner L. Wittgenstein political philosophy R. Koselleck speech acts
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