Search results for "integral"
showing 10 items of 902 documents
Rollio delle navi in presenza di onde modellate come processi gaussiani e poissoniani agenti simultaneamente.
2008
Obiettivo del presente lavoro è l’estensione del metodo della path integral solution (PIS) per lo studio della dinamica del rollio delle navi in presenza di onde modellate come processi gaussiani e poissionani agenti simultaneamente. Si è proceduto dapprima a mostrare come la PIS consenta di valutare l’evoluzione temporale della funzione densità di probabilità (PDF) del processo di risposta, applicando il metodo ad equazioni differenziali stocastiche soggette a forzanti esterne gaussiane e poissoniane. Successivamente si è trattato il caso di un sistema non lineare soggetto ad entrambi i rumori gaussiano e poissoniano agenti contestualmente. Si è infine affrontato sia analiticamente che num…
La violencia de género al País Valencià. Diagnóstico y propuestas de las profesionales
2018
La violencia contra la mujer se ha convertido en una problemática social con un alto coste para las personas que la padecen de forma directa e indirecta, y además se trata de un área de intervención en la que se encuentran involucradas profesionales de diferentes ámbitos: policial, sanitario, judicial, servicios sociales, educación... que trabajan en muchas ocasiones sin la suficiente preparación y sin los recursos y medios que serían necesarios (Canet, 2017). Es de gran importancia a la hora de intervenir en los casos de violencia de género actuar a nivel macro social, con todos los elementos del sistema patriarcal que fomentan y perpetúan la violencia a nivel cultural, económico, político…
Role of oxoproline in the regulation of neutral amino acid transport across the blood-brain barrier.
1996
Regulation of neutral amino acid transport was studied using isolated plasma membrane vesicles derived from the bovine blood-brain barrier. Neutral amino acids cross the blood-brain barrier by facilitative transport system L1, which may allow both desirable and undesirable amino acids to enter the brain. The sodium-dependent amino acid systems A and Bo,+ are located exclusively on abluminal membranes, in a position to pump unwanted amino acids out. gamma-Glutamyl transpeptidase, the first enzyme of the gamma-glutamyl cycle, is an integral protein of the luminal membrane of the blood-brain barrier. We demonstrate that oxoproline, an intracellular product of the gamma-glutamyl cycle, stimulat…
Refolding of the integral membrane protein light-harvesting complex II monitored by pulse EPR
2009
The major light-harvesting chlorophyll a / b complex (LHCII) of the photosynthetic apparatus in plants self-organizes in vitro. The recombinant apoprotein, denatured in dodecyl sulfate, spontaneously folds when it is mixed with its pigments, chlorophylls, and carotenoids in detergent solution, and assembles into structurally authentic LHCII in the course of several minutes. Pulse EPR techniques, specifically double-electron-electron resonance (DEER), have been used to analyze protein folding during this process. Pairs of nitroxide labels were introduced site-specifically into recombinant LHCII and shown not to affect the stability and function of the pigment-protein complex. Interspin dist…
The membrane environment modulates self-association of the human GpA TM domain--implications for membrane protein folding and transmembrane signaling.
2010
Abstract The influence of lipid bilayer properties on a defined and sequence-specific transmembrane helix–helix interaction is not well characterized yet. To study the potential impact of changing bilayer properties on a sequence-specific transmembrane helix–helix interaction, we have traced the association of fluorescent-labeled glycophorin A transmembrane peptides by fluorescence spectroscopy in model membranes with varying lipid compositions. The observed changes of the glycophorin A dimerization propensities in different lipid bilayers suggest that the lipid bilayer thickness severely influences the monomer–dimer equilibrium of this transmembrane domain, and dimerization was most effici…
Generation of proteoliposomes from subcellular fractions.
1998
Intracellular membranes are highly dynamic, yet they retain their identity and functional characteristics. Integral membrane proteins, which must confer this specific membrane identity, remain poorly characterized at the biochemical level, largely because detergent-mediated solubilization is required for purification and analysis, and several properties of integral membrane proteins can only be investigated when the molecule is properly embedded in a lipid bilayer. We present a method for the efficient reconstitution into proteoliposomes of integral membrane proteins from subcellular fractions. Integral membrane proteins were identified on high-resolution two-dimensional gels after selectiv…
Exploring Students’ Metacognitive Knowledge: The Case of Integral Calculus
2020
Previous studies of integral calculus have mainly explored students&rsquo
Finite type invariants of knots in homology 3-spheres with respect to null LP-surgeries
2017
We study a theory of finite type invariants for null-homologous knots in rational homology 3-spheres with respect to null Lagrangian-preserving surgeries. It is an analogue in the setting of the rational homology of the Goussarov-Rozansky theory for knots in integral homology 3-spheres. We give a partial combinatorial description of the graded space associated with our theory and determine some cases when this description is complete. For null-homologous knots in rational homology 3-spheres with a trivial Alexander polynomial, we show that the Kricker lift of the Kontsevich integral and the Lescop equivariant invariant built from integrals in configuration spaces are universal finite type i…
Some coincidence and periodic points results in a metric space endowed with a graph and applications
2015
The purpose of this paper is to obtain some coincidence and periodic points results for generalized $F$-type contractions in a metric space endowed with a graph. Some examples are given to illustrate the new theory. Then, we apply our results to establishing the existence of solution for a certain type of nonlinear integral equation.
Fixed points for asymptotic contractions of integral Meir-Keeler type
2012
In this paper we introduce the notion of asymptotic contraction of integral Meir-Keeler type on a metric space and we prove a theorem which ensures existence and uniqueness of fixed points for such contractions. This result generalizes some recent results in the literature.