Search results for "interactions."

Serological Tests Do Not Predict Residual Fibrosis in Hepatitis C Cirrhotics with a Sustained Virological Response to Interferon

2016

BACKGROUND AND AIM: Liver biopsy (LB) has lost popularity to stage liver fibrosis in the era of highly effective anti-hepatitis C virus (HCV) therapy, yet diagnosis of persistent cirrhosis may have important implications following HCV eradication. As performance of serological non-invasive tests (NITs) to predict residual fibrosis in non-viremic HCV patients is unknown, we investigated accuracy of NITs to predict residual fibrosis in cirrhotics after a sustained virological response (SVR) to interferon (IFN). METHODS: Thirty-eight patients with a pre-treatment histological diagnosis of cirrhosis and a 48–104 months post-SVR LB were tested with APRI, CDS, FIB-4, FibroQ, Forns Score, GUCI Ind…

Stratégies d'influences et politiques de maîtrise de la croissance locale

2010

Over the last ten years, real estate prices have risen considerably and accordingly to most observers, this can at least partly be attributed to an insufficient supply, due to local growth control measures. This thesis tries to understand what motivates local authorities implementing such policies. Local politicians are considered as opportunistic and their decision is modelled as the result of a political struggle between different land-related interests. This game for influence mainly opposes the owners of developed and undeveloped land, who find allies amongst local business interests that might form growth or ideas machines. Our first model describes this struggle under different hypoth…

A Simultaneous Observation of Lightning by ASIM, Colombia-Lightning Mapping Array, GLM, and ISS-LIS

2021

The Atmosphere-Space Interactions Monitor (ASIM) on the International Space Station (ISS) provides optical radiances and images of lightning flashes in several spectral bands. This work presents a lightning flash simultaneously observed from space by ASIM, the Geostationary Lightning Mapper (GLM) and the Lightning Imaging Sensor on the International Space Station (ISS-LIS); and from ground by the Colombia-Lightning Mapping Array (Colombia-LMA). Volumetric weather radar provides reflectivity data to help to interpret the effects of the cloud particles on the observed optical features. We found that surges in radiance in the band at 777.4 nm appear to be related mostly with lightning processe…

A fractional viscoelastic non-local Timoshenko beam

2014

MECHANICAL RESPONSE OF BERNULLI EULER BEAMS ON FRACTIONAL ORDER ELASTIC FOUNDATION

2014

Biodegradable Protein Nanocontainers

2015

The application of synthetic polymers for drug delivery often requires tremendous efforts to ensure biocompatibility and -degradation. To use the body's own substances can help to overcome these problems. Herein, we present the first synthesis of nanocontainers entirely composed of albumin proteins. These protein nanocontainers (PNCs) were loaded with hydrophilic compounds and release of the payload is triggered through natural lysis in vitro in human monocyte-derived dendritic cells (moDCs). No aggregation of PNCs in human blood plasma was observed, indicating stability for blood circulation. As the PNCs were readily taken up by moDCs, they are considered as a promising delivery platform f…

New analysis of ηπ tensor resonances measured at the COMPASS experiment

2018

We present a new amplitude analysis of the $\eta\pi$ $D$-wave in $\pi^- p\to \eta\pi^- p$ measured by COMPASS. Employing an analytical model based on the principles of the relativistic $S$-matrix, we find two resonances that can be identified with the $a_2(1320)$ and the excited $a_2^\prime(1700)$, and perform a comprehensive analysis of their pole positions. For the mass and width of the $a_2$ we find $M=(1307 \pm 1 \pm 6)$~MeV and $\Gamma=(112 \pm 1 \pm 8)$~MeV, and for the excited state $a_2^\prime$ we obtain $M=(1720 \pm 10 \pm 60)$~MeV and $\Gamma=(280\pm 10 \pm 70)$~MeV, respectively.

Kinetics of doublet formation in bicomponent magnetic suspensions: The role of the magnetic permeability anisotropy

2017

Micron-sized particles (microbeads) dispersed in a suspension of magnetic nanoparticles, i.e., ferrofluids, can be assembled into different types of structures upon application of an externalmagnetic field. This paper is devoted to theoretical modeling of a relative motion of a pair of microbeads (either soft ferromagnetic or diamagnetic) in the ferrofluid under the action of applied uniform magnetic field which induces magnetic moments in the microbeads making them attracting to each other. The model is based on a point-dipole approximation for the magnetic interactions between microbeads mediated by the ferrofluid; however, the ferrofluid is considered to possess an anisotropic magnetic p…

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use…

2013

This review encompasses the most important advances in liver functions and hepatotoxicity and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested, zonated lobules, the liver consists of approximately 80 % hepatocytes and 20 % non-parenchymal cells, the latter being involved in a secondary phase that may dramatically aggravate the initial damage. Hepatotoxicity, as well as hepatic metabolism, is controlled by a set of nuclear receptors (including PXR, CAR, HNF-4α, FXR, LXR, SHP, VDR and PPAR) and signaling pathways. When isolating liver cells, some pathways are activated, e.g., the RAS/MEK/ERK pathway, whereas others are silenced (e.g. HNF-4α), resulting in…

Yeast–yeast interactions revealed by aromatic profile analysis of Sauvignon Blanc wine fermented by single or co-culture of non-Saccharomyces and Sac…

2012

International audience; There has been increasing interest in the use of selected non-Saccharomyces yeasts in co-culture with Saccharomyces cerevisiae. The main reason is that the multistarter fermentation process is thought to simulate indigenous fermentation, thus increasing wine aroma complexity while avoiding the risks linked to natural fermentation. However, multistarter fermentation is characterised by complex and largely unknown interactions between yeasts. Consequently the resulting wine quality is rather unpredictable. In order to better understand the interactions that take place between non-Saccharomyces and Saccharomyces yeasts during alcoholic fermentation, we analysed the vola…