Search results for "interphase"
showing 10 items of 50 documents
Effect of reducing agents on the acidification capacity and the proton motive force of Lactococcus lactis ssp. cremoris resting cells.
2002
International audience; Reducing agents are potential inhibitors of the microbial growth. We have shown recently that dithiothreitol (DTT), NaBH(4) and H(2) can modify the proton motive force of resting cells of Escherichia coli by increasing the membrane protons permeability [Eur. J. Biochem. 262 (1999) 595]. In the present work, the effect of reducing agents on the resting cells of Lactococcus lactis ssp. cremoris, a species widely employed in dairy processes was investigated. DTT did not affect the acidification nor the DeltapH, in contrast to the effect previously reported on E. coli. The DeltaPsi was slightly increased (30 mV) at low pH (pH 4) in the presence of 31 mM DTT or 2.6 mM NaB…
Unique pharmacology of KAR-2, a potential anti-cancer agent: absorption modelling and selective mitotic spindle targeting.
2008
Abstract Bis-indols are a large group of the anti-cancer agents, which effectively arrest the uncontrolled division of the cancerous cells. Their use in clinical chemotherapy is still limited because of: (i) the non-specific targeting of the mitotic cells; (ii) low bioavailability of the drugs. KAR-2 has been identified as a tubulin binding agent which displays significantly lower cytotoxicity but favourable anti-cancer potency than its mother molecule, vinblastine. The objective of this paper, on one hand, was to show that the human intestinal epithelial Caco-2 cells, used for pharmacokinetic studies display distinct sensitivity against KAR-2 and vinblastine due to their distinct targeting…
Field Induced Evolution of Nanoscale Structures in Relaxor PLZT Ceramics
2005
Abstract The kinetics of the nanoscale structures under application of bipolar and unipolar ac field was investigated by recording of the switching charge in wide temperature and field range in hot-pressed relaxor PLZT ceramics. Original analysis of the switching charge data was based on the consideration of the field induced transformation as an evolution of the nanoscale domain structure with nanoscale nonpolar inclusions. We have shown that the inhomogeneous depolarization field produced by the bound charges existing at the interphase boundaries play the key role in spontaneous backswitching effects.
A phase-field model for strain localization analysis in softening elastoplastic materials
2019
Abstract The present paper deals with the localization of strains in those structures consisting of materials exhibiting plastic softening response. It is assumed that strain localization develops in a finite thickness band separated from the remaining part of the structure by weak discontinuity surfaces. In view of the small thickness of the band with respect to the dimensions of the structure, the interphase concept is used for the mechanical modeling of the localization phenomenon. We propose a formulation for the quasi-static modeling of strain localization based on a phase-field approach. In this sense, the localization band is smeared over the volume of the structure and a smooth tran…
A green method to prepare nanosilica modified graphene oxide to inhibit nanoparticles re-aggregation during melt processing
2017
Abstract A graphene oxide-silica nanohybrid (GOS), self-assembled into a lasagna -like structure, was prepared in water and used as a filler for the melt preparation of polyamide 6 (PA6)-based nanocomposites. For sake of comparison, PA6-based materials were prepared under the same processing conditions by adding GO only or a physical mixture of GO and silica (GO+S). All the materials were characterized from a morphological, spectroscopic, thermal, dynamic-mechanical (DMA) and mechanical point of view. For all the nanocomposites, the interphase was studied either by analyzing loss factor plots coming from DMA measurements and by implementing a novel approach, i.e. combining solvent extractio…
CuO nanoparticle filled vinyl-ester resin nanocomposites: Fabrication, characterization and property analysis
2007
Abstract Both unmodified cupric oxide (CuO) nanoparticles and those functionalized with a bi-functional coupling agent methacryloxypropyl-trimethoxysilane (MPS) were used to fabricate vinyl-ester resin polymeric nanocomposites. The nanoparticle functionalization was observed to have a significant effect on the physical properties of the cupric oxide filled vinyl-ester resin nanocomposite. Thermal degradation study by thermo-gravimetric analysis (TGA) showed the increased thermo-stability in the functionalized-nanoparticle-filled vinyl-ester resin nanocomposites as compared with the unmodified-nanoparticle-filled counterparts. The more uniform particle dispersion and the chemical bond betwee…
Influence of oxidation level of graphene oxide on the mechanical performance and photo-oxidation resistance of a polyamide 6
2019
The aim of this work is to study the relationship between the chemical-physical properties of graphene oxide (GO) and the performance of a polyamide 6 (PA6) in terms of mechanical reinforcement and resistance to UV-exposure. For this purpose, two samples of GO possessing different oxidation degrees were added (0.75 wt.%) to PA6 by way of a two-step technique and the materials achieved were carefully analysed from a morphological, chemical-physical, mechanical point of view. Photo-oxidation tests were carried out to assess the performance of this class of nanohybrids after 240 h of UV-exposure. The results reveal that both nanocomposites exhibit enhanced mechanical performance and durability…
The interphase finite element
2011
Mesomodelling of structures made of heterogeneous materials requires the introduction of mechanical models which are able to simulate the interactions between the adherents. Among these devices is quite popular the zero thickness interface (ZTI) model where the contact tractions and the displacement discontinuities are the primary static and kinematic variables. In some cases the joint response depends also on the internal stresses and strains within the thin layer adjacent to the joint interfaces. The interphase model, taking into account these additional variables, represents a sort of enhanced ZTI. In this paper a general theoretical formulation of the interphase model is reported and an…
Dielectric memory effects of (Mn, Fe, Co, Cu, Eu) doped PLZT ceramics
1992
Abstract Dielectric memory effects—effect of thermal memory (ETM) and effect of electric field memory (EFM) have been studied in (Mn, Fe, Co, Cu, Eu) doped PLZT ceramics. The obtained results have been discussed on the assumption that the ETM and EFM depends on relaxation of domain and interphase (polar and nonpolar) boundaries influenced by changes of defects conditions at doping.
Heterogeneous structures studied by an interphase elasto-plastic damaging model
2013
Heterogeneous materials present a mechanical response strongly dependent on the static and kinematic phenomena occurring in the constituents and at their joints. At the mesoscopic level the interaction between the units is simulated by mean of apposite mechanical devices such as the zero thickness interface model where contact tractions and displacement discontinuities are the primary static and kinematic variables respectively. In heterogeneous materials the response also depends on joint internal stresses. The introduction of internal stresses brings to the interphase model or an enhancement of the classical zero-thickness interface. With the term 'interphase' we shall mean a layer separa…