Search results for "interval"

showing 10 items of 1703 documents

Impact of nutritional status on the oral bioavailability of leucine administered to rats as part of a standard enteral diet.

2010

Summary Background To investigate the absorption and relative bioavailability of leucine administered orally as part of an enteral diet in well and malnourished animals. Methods Two groups – RN (regular nutrition) and PCR (protein-calorie restricted) – were fed with different diets for 23–25 days. Rats from each group were assigned randomly to one of three treatments (water, T-Diet Plus Standard ® (problem) or Isosource ST ® (reference)) administered in single ( N  = 76) or multiple ( N  = 39) doses. Blood samples were assayed for leucine content. Area under the curve (AUC) was calculated by non-compartmental analysis. Log-transformed AUC(s) were statistically compared by analysis of varian…

MaleAdministration OralBiological AvailabilityNutritional StatusCritical Care and Intensive Care MedicineMultiple dosingEnteral administrationAbsorptionAnimal scienceEnteral NutritionLeucineDiet Protein-RestrictedMedicineAnimalsFood scienceRats WistarNutrition and DieteticsDose-Response Relationship Drugbusiness.industryArea under the curveNutritional statusConfidence intervalBioavailabilityDietRatsArea Under CurveAnalysis of varianceLeucinebusinessEnergy IntakeClinical nutrition (Edinburgh, Scotland)
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ATP4A autoimmunity and Helicobacter pylori infection in children with type 1 diabetes

2014

Summary Persistent presence of ATP4A autoantibodies (ATP4AA) directed towards parietal cells is typical for atrophic body gastritis (ABG), an autoimmune disease associated with type 1 diabetes. We assessed whether Helicobacter pylori (Hp) infection might be associated with positivity for ATP4AA in children with type 1 diabetes. Sera were collected from 70 (38♀) type 1 diabetes children [aged 13·2 ± 4·5 years, age at diagnosis 8·8 ± 4·3 years, diabetes duration 4·5 ± 3·8 years, mean HbA1c 7·8 ± 1·6% (62 ± 17·5 mmol/mol)] seen at the regional diabetes clinic in Katowice, Poland. Patients were tested concurrently for Hp infection by means of a 13C urea breath test. ATP4AA were measured using a…

MaleAdolescentAutoimmune Gastritisautoantibodiestype 1 diabetesImmunologyAutoimmunityautoimmune gastritismedicine.disease_causeparietal cellAutoimmunityAutoimmune DiseasesHelicobacter InfectionsH(+)-K(+)-Exchanging ATPaseYoung AdultSex FactorsmedicineImmunology and AllergyHumansChildAutoimmune diseaseType 1 diabetesbiologyHelicobacter pyloribusiness.industryAutoantibodyOriginal ArticlesHelicobacter pyloribiology.organism_classificationmedicine.diseaseConfidence intervalCross-Sectional StudiesDiabetes Mellitus Type 1Child PreschoolImmunologyFemaleGastritismedicine.symptombusinessClinical and Experimental Immunology
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Coverage intervals for trace elements in human scalp hair are site specific.

2014

Coverage intervals for trace elements in human scalp hair commonly provide the basis for interpreting laboratory results and also in comparative decision-making processes regarding exposure risk assessment. This short communication documents, by some examples, that those computed for human hair are to be considered site specific, as they reflect local environmental conditions; also each geographic area has a typical profile of hair elemental composition of its inhabitants. Therefore, the levels of trace elements in hair are not strictly comparable between different areas of the world. This issue is particularly relevant when identification of anomalous environmental exposures are requested …

MaleAdolescentHealth Toxicology and MutagenesisBiologyToxicologyRisk AssessmentToxicologymedicineHumansChildSicilyPharmacologyElemental compositionScalpintegumentary systemGeographic areaGeneral MedicineLaboratory resultsSettore GEO/08 - Geochimica E VulcanologiaTrace (semiology)medicine.anatomical_structureItalyMetalsScalpCoverage intervals Hair composition Biomonitoring Risk assessment Trace elementsEnvironmental PollutantsFemaleCartographyEnvironmental MonitoringHairEnvironmental toxicology and pharmacology
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Concentration and reference interval of trace elements in human hair from students living in Palermo, Sicily (Italy).

2010

Trace element contents in specimens of hair collected from 137 children aged 11–13 years old, living in Palermo (Sicily, Italy) were determined by ICP-MS. This work reports analytical data for the following 19 elements: Al, As, Ba, Cd, Co, Cr, Cu, Li, Mn, Mo, Ni, Pb, Rb, Sb, Se, Sr, U, V and Zn. The most abundant chemical elements were zinc and copper (Zn > Cu), with concentrations exceeding 10microg/g (Zn = 189.2microg/g; Cu= 22.9microg/g). Other elements with concentrations greater than 1microg/g were, in order of abundance, Al > Sr > Ba > Pb. The remaining elements were all below 1microg/g. The average elemental concentrations in hair were statistically compared by Kolmogorov–Smirnov’s t…

MaleAdolescentHealth Toxicology and MutagenesisStatistical analysichemistry.chemical_elementZincToxicologyMass SpectrometryArsenicHumansStatistical analysisChildSicilyPharmacologyChemistryHair analysisTrace elementReference intervalsGeneral MedicineReference intervalsSettore GEO/08 - Geochimica E VulcanologiaHuman biomonitoringMetalsEnvironmental chemistryTrace elementEnvironmental PollutantsFemaleEnvironmental MonitoringHairEnvironmental toxicology and pharmacology
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Childhood leukaemia risk and residential proximity to busy roads

2018

BACKGROUND: Current evidence suggests that childhood leukaemia can be associated with residential traffic exposure; nevertheless, more results are needed to support this conclusion. OBJECTIVES: To ascertain the possible effects of residential proximity to road traffic on childhood leukaemia, taking into account traffic density, road proximity and the type of leukaemia (acute lymphoid leukaemia or acute myeloid leukaemia). METHODS: We conducted a population-based case-control study of childhood leukaemia in Spain, covering the period 1990-2011. It included 1061 incidence cases gathered from the Spanish National Childhood Cancer Registry and those Autonomous Regions with 100% coverage, and 64…

MaleAdolescentPopulationLogistic regressionRisk AssessmentOdds03 medical and health sciences0302 clinical medicineRisk Factorshemic and lymphatic diseasesResidential proximityOdds RatioMedicineHumans030212 general & internal medicineRegistriesRisk factoreducationChildlcsh:Environmental sciencesGeneral Environmental Sciencelcsh:GE1-350Childhood Cancer Registryeducation.field_of_studyLeukemiabusiness.industryIncidence (epidemiology)IncidenceChildhood leukaemiaInfant NewbornInfantCase-control studyOdds ratioConfidence intervalMotor VehiclesLogistic ModelsSpain030220 oncology & carcinogenesisCase-Control StudiesChild PreschoolHousingFemaleTraffic densitybusinessDemography
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Trends in hospitalization of patients with diabetes mellitus in Ghana from 2012 to 2017 with predictions to 2032

2021

Abstract Background This study explores sociodemographic and health factors associated with hospitalizing diabetes mellitus (DM) patients and estimates the number of future hospitalizations for DM in Ghana. Methods We conducted a secondary analysis using nationally representative patient hospitalization data provided by the Ghana Health Service and projected population counts from the Ghana Statistical Service. Data were stratified by year, age, sex and region. We employed Poisson regression to determine associations between sociodemographic and health factors and hospitalization rates of DM patients. Using projected population counts, the number of DM-related hospitalizations for 2018 thro…

MaleAdultHealth (social science)PopulationRate ratioGhanasymbols.namesakeOlder patientsSecondary analysisDiabetes mellitusDiabetes MellitusHumansMedicinePoisson regressioneducationAgededucation.field_of_studybusiness.industryPublic Health Environmental and Occupational HealthPublic health educationGeneral Medicinemedicine.diseaseConfidence intervalHospitalizationsymbolsFemalebusinessDemographyInternational Health
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Gazpacho consumption is associated with lower blood pressure and reduced hypertension in a high cardiovascular risk cohort. Cross-sectional study of …

2013

[Background and aim]: Hypertension is a major public health problem and a leading cause of death and disability in both developed and developing countries, affecting one-quarter of the world's adult population. Our aim was to evaluate whether the consumption of gazpacho, a Mediterranean vegetable-based cold soup rich in phytochemicals, is associated with lower blood pressure (BP) and/or reduced prevalence of hypertension in individuals at high cardiovascular risk.

MaleAgingCross-sectional studyEndocrinology Diabetes and MetabolismPhytochemicalsMedicine (miscellaneous)Diet MediterraneanLogistic regressionCohort StudiesSolanum lycopersicumFunctional FoodRisk FactorsVegetablesPrevalenceCookingCause of deathAged 80 and overeducation.field_of_studyNutrition and DieteticsMiddle AgedGazpacho (Mediterranean vegetable soup)Cardiovascular DiseasesPolifenolsCohortHypertensionBlood pressureFemaleHipertensióCardiology and Cardiovascular MedicineGaspatxomedicine.medical_specialtyPopulationGazpachoPressió sanguíniaMediterranean cookingInternal medicineCuina mediterràniamedicineHumanseducationAgedbusiness.industryPolyphenolsPREDIMED studyOdds ratioConfidence intervalCross-Sectional StudiesBlood pressureSpainFruitbusiness
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Olive oil consumption is associated with lower frailty risk: a prospective cohort study of community-dwelling older adults

2021

Abstract Background There is no evidence on the specific beneficial association of the main types of olive oil consumption with frailty. Objective The aim was to assess the relationship between olive oil consumption and incident frailty in community-dwelling older adults. Design Prospective cohort. Setting Participants were recruited in 2008–10 and follow-up through 2013. Subjects In total, 1,896 older adults aged 60+. Methods At baseline, olive oil and other food consumption was collected using a validated dietary history. Incident frailty was defined as having at least three of the following five Fried-based criteria: low physical activity, fatigue, slow walking, muscle weakness and unint…

MaleAgingFrail ElderlyLogistic regressionCohort StudiesfoodWeight lossEnvironmental healthHumansMedicineProspective StudiesProspective cohort studyOlive OilAgedFrailtybusiness.industryNutritional epidemiologyConfoundingfood.culinary_measureGeneral MedicineOdds ratioConfidence intervalFemaleTablespoonIndependent LivingGeriatrics and Gerontologymedicine.symptombusinessAge and Ageing
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Objectively measured physical activity and physical performance in old age

2017

Abstract Background: Physical performance is a key factor that determines how older people cope with daily tasks and maintain independency. There is strong evidence suggesting that physical activity (PA) is important in maintaining physical performance in old age. However, most studies have been done using self-reported PA. Our aim was to explore the association between objectively measured PA and physical performance in old age. Methods: We studied 695 participants (mean age 70.7 years, SD 2.7) from the Helsinki Birth Cohort Study. Physical performance was assessed with the Senior Fitness Test (SFT) and PA with a multisensory activity monitor SenseWear Pro 3 Armband. Results: Total volume …

MaleAgingFunctional trainingmedicine.medical_specialtyPhysical activityfyysinen toimintakykyphysical activityFitness TrackersMotor ActivityArticleSenior Fitness Testsenior fitness testsolder people03 medical and health sciences0302 clinical medicinePredictive Value of TestsNegatively associatedHumansMedicinephysical functioning030212 general & internal medicineExerciseGeriatric AssessmentAgedbusiness.industryAge Factorsta3141ta3142General Medicinephysical performanceActigraphyConfidence intervalCross-Sectional StudiesFitness testikääntyminenPhysical FitnessAgeingPhysical performanceageingPhysical therapyFemaleSedentary BehaviorGeriatrics and GerontologybusinessOlder people030217 neurology & neurosurgery
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Adapting and validating the Rosenberg Self-Esteem Scale for elderly Spanish population.

2019

ABSTRACTObjectives:This study aims to adapt and validate the most common measure of self-esteem, the Rosenberg Self-Esteem Scale (RSES), in the elderly Spanish population based on the initial one-factor model proposed by the author of the scale.Design:The factorial validity of the scale was tested using confirmatory factor analysis.Setting:The study was carried out in the city of Valencia (Spain).Participants:A total of 231 elderly people with a mean age 72.68 (SD=8.55).Measurements:The participants completed the questionnaire RSES for the validation process, sociodemographic data and Mini-Mental State Examination.Results:Confirmatory factor analysis with a five-item structure for the one-f…

MaleAgingScale (ratio)Psychometricsmedia_common.quotation_subject050109 social psychology050105 experimental psychologyStructural equation modelingCronbach's alphaSurveys and QuestionnairesChi-square testHumans0501 psychology and cognitive sciencesmedia_commonAgedAged 80 and over05 social sciencesSelf-esteemRosenberg self-esteem scaleReproducibility of ResultsMiddle AgedConfirmatory factor analysisConfidence intervalSelf ConceptPsychiatry and Mental healthClinical PsychologySpainFemaleGeriatrics and GerontologyPsychologyFactor Analysis StatisticalGerontologyClinical psychologyInternational psychogeriatrics
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