Search results for "isä"
showing 10 items of 1004 documents
G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids
2022
The nuclear export factor CRM1-mediated pathway is known to be important for the nuclear egress of progeny parvovirus capsids in the host cells with virus-mediated cell cycle arrest at G2/M. However, it is still unclear whether this is the only pathway by which capsids exit the nucleus. Our studies show that the nuclear egress of DNA-containing full canine parvovirus. capsids was reduced but not fully inhibited when CRM1-mediated nuclear export was prevented by leptomycin B. This suggests that canine parvovirus capsids might use additional routes for nuclear escape. This hypothesis was further supported by our findings that nuclear envelope (NE) permeability was increased at the late stages…
Spatiotemporal and gender-specific parasitism in two species of gobiid fish
2018
Parasitism is considered a major selective force in natural host populations. Infections can decrease host condition and vigour, and potentially influence, for example, host population dynamics and behavior such as mate choice. We studied parasite infections of two common marine fish species, the sand goby (Pomatoschistus minutus) and the common goby (Pomatoschistus microps), in the brackish water Northern Baltic Sea. We were particularly interested in the occurrence of parasite taxa located in central sensory organs, such as eyes, potentially affecting fish behavior and mate choice. We found that both fish species harbored parasite communities dominated by taxa transmitted to fish through …
Disparities in Accessing Sexual and Reproductive Health Services at the Intersection of Disability and Female Adolescence in Tanzania
2021
Despite at times having greater needs for sexual and reproductive health (SRH) services, adolescents with disabilities often face challenges when trying to access them. This inaccessibility is further exacerbated during female adolescence. The qualitative study examines how SRH services respond to the characteristics of Tanzanian adolescent females with disabilities. We used the method of empathy-based stories to investigate the perceptions of 136 adolescent females with disabilities of their access to SRH services in Tanzania. The study used thematic content analysis and the Levesque model of health care access was applied as an analytical framework. The results demonstrate that discrimina…
Sisäinen markkinointi johtamisena : tapaustutkimus konepajateollisuuden projektiorganisaatiosta
2009
The objective of this study was to increase the understanding of the management of internal marketing. The theoretical objective was to specify the mutual relation of the concepts of internal marketing and management. On the basis of an analysis of the two concepts and of research literature, a managerial model of the management of internal marketing was built as a theoretical frame of reference.The empirical part of the study examined how the members of the personnel in the case organization built their perception of internal marketing management in their mutual interaction on the basis of their experiences and their feelings. On the basis of the frame of reference model and the empirical …
Kirja-arvostelut alustataloudessa – esimerkkinä käyttäjälähtöiset arvostelut Instagramissa
2021
Kulttuurituotteita eivät sosiaalisen median aikakaudella enää arvostele julkisesti vain perinteisen median ammattikriitikot, vaan myös tavalliset ihmiset osallistuvat teosten julkiseen arvottamiseen erilaisilla digitaalisilla alustoilla. Tarkastelemme tässä artikkelissa kirjallisuusarvosteluja osana alustoitunutta kulttuurituotantoa esimerkkinämme käyttäjälähtöiset kirja-arvostelut erityisesti kuvasovellus Instagramissa. Instagramiin on vakiintunut kirjallisuuskeskusteluyhteisö, jota kutsutaan maailmanlaajuisesti nimellä Bookstagram mutta jolla on myös paikallisia tai alueellisia muotoja, kuten suomalainen Kirjagram. Kysymme, miten käyttäjäarvostelijat esiintyvät niissä arvostelulle määrite…
Urheilujournalismi vallan vahtikoirana? : tapauskohtaisessa tarkastelussa huippu-urheilun muutostyötä käsittelevä uutisointi suomalaisissa sanomalehd…
2018
Artikkelin tutkimuskohteena on suomalaisen sanomalehdistön uutisointi vuosina 2010–2012 tehdystä huippu-urheilun muutostyöstä, jota opetus- ja kulttuuriministeriö rahoitti 2,6 miljoonalla eurolla. Tutkimuksen tavoitteena on selvittää, millainen vallan vahtikoira urheilujournalismi on. Tutkimusaineisto koostuu levikiltään kolmen Suomen suurimman päivälehden (Aamulehti, Helsingin Sanomat ja Turun Sanomat) ja maan molempien iltapäivälehtien (Iltalehti ja Ilta-Sanomat) kaikesta muutostyötä käsittelevästä uutisoinnista lehtien painetuissa versioissa. Tarkasteluajanjakso on rajattu Huippu-urheilun muutosryhmän (HuMu) loppuraportin julkistamista (5.12.2012) seuranneelle puolen vuoden ajalle (6.12.…
Poison frog social behaviour under global change: potential impacts and future challenges
2022
AbstractThe current and cascading effects of global change challenges the interactions both between animal individuals (i.e. social and sexual behaviour) and the environment they inhabit. Amphibians are an ecologically diverse class with a wide range of social and sexual behaviours, making them a compelling model to understand the potential adaptations of animals faced with the effects of human-induced rapid environmental changes (HIREC). Poison frogs (Dendrobatoidea) are a particularly interesting system, as they display diverse social behaviours that are shaped by conspecific and environmental interactions, thus offering a tractable system to investigate how closely related species may re…
Factors influencing adjustment to remote work: Employees’ initial responses to the covid-19 pandemic
2021
The COVID-19 crisis has disrupted when, where, and how employees work. Drawing on a sample of 5452 Finnish employees, this study explores the factors associated with employees’ abrupt adjustment to remote work. Specifically, this study examines structural factors (i.e., work independence and the clarity of job criteria), relational factors (i.e., interpersonal trust and social isolation), contextual factors of work (i.e., change in work location and perceived disruption), and communication dynamics (i.e., organizational communication quality and communication technology use (CTU)) as mechanisms underlying adjustment to remote work. The findings demonstrate that structural and contextual fac…
The fragility of Finnish parliamentary democracy at the moment when Prussianism fell
2019
The Finnish case is in many ways illustrative of the complexities of democratisation after World War I. Finland found itself at the nexus of a Swedish constitutional tradition, legalism and ideological controversies adopted from Imperial Germany, the radicalised Russian Revolution, and Western parliamentary democracy. After having been a model for reformers demanding women’s suffrage, for instance, the country found itself in autumn 1918 going in the opposite direction to almost all other European countries. This article analyses the fragility of Finnish parliamentary democracy then, contrasting it with longer-term trends supportive of democratisation. ‘Democracy’ had been the goal for mos…
Inbreeding does not alter the response to an experimental heat wave in a freshwater snail
2019
Global climate change affects natural populations of many species by increasing the average temperature and the frequency of extreme weather events (e.g. summer heat waves). The ability of organisms to cope with these environmental changes can, however, depend on their genetic properties. For instance, genetic load owing to inbreeding could alter organisms’ responses to climate change-mediated environmental changes but such effects are often overlooked. We investigated the effects of an experimental heat wave (25°C versus 15°C) on life history (reproduction, size) and constitutive immune defence traits (phenoloxidase-like and antibacterial activity of haemolymph) in relation to inbreeding b…