Search results for "itä"

showing 10 items of 310 documents

Candidate genetic pathways for attention-deficit/hyperactivity disorder (ADHD) show association to hyperactive/impulsive symptoms in children with AD…

2013

Item does not contain fulltext OBJECTIVE: Because multiple genes with small effect sizes are assumed to play a role in attention-deficit/hyperactivity disorder (ADHD) etiology, considering multiple variants within the same analysis likely increases the total explained phenotypic variance, thereby boosting the power of genetic studies. This study investigated whether pathway-based analysis could bring scientists closer to unraveling the biology of ADHD. METHOD: The pathway was described as a predefined gene selection based on a well-established database or literature data. Common genetic variants in pathways involved in dopamine/norepinephrine and serotonin neurotransmission and genes involv…

Malegenetic pathwaysMedizinSocial SciencesGenome-wide association studyDCN PAC - Perception action and controlSeverity of Illness Index/dk/atira/pure/sustainabledevelopmentgoals/clean_water_and_sanitationneuritic outgrowth2738 Psychiatry and Mental HealthDOPAMINE0302 clinical medicineDevelopmental and Educational PsychologyIsraelChildQUANTITATIVE TRAITS10058 Department of Child and Adolescent PsychiatryGenomic disorders and inherited multi-system disorders [DCN PAC - Perception action and control IGMD 3]EuropePsychiatry and Mental healthattention-deficit/hyperactivity disorder symptomsPhenotypeChild PreschoolFemalemedicine.symptomPsychologySDG 6 - Clean Water and Sanitationmedicine.drugClinical psychologymedicine.medical_specialtyDIAGNOSTIC-APPROACHAdolescentGenotypeLARGE MULTICENTER ADHDIDENTIFIES ASSOCIATIONDEFICIT HYPERACTIVITY DISORDERDCN MP - Plasticity and memoryneurotransmitter systems610 Medicine & healthQuantitative trait locusHyperkinesisImpulsivityMental health [NCEBP 9]Genomic disorders and inherited multi-system disorders DCN MP - Plasticity and memory [IGMD 3]03 medical and health sciencesDopamineRating scalemedicineCriterion validityddc:61Attention deficit hyperactivity disorderHumansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersDCN PAC - Perception action and control NCEBP 9 - Mental healthGENOME-WIDE ASSOCIATIONNITRIC-OXIDE SYNTHASEPsychiatryGenetic Association StudiesMETAANALYSISPsychiatric Status Rating Scales3204 Developmental and Educational Psychologymedicine.disease030227 psychiatryAttention Deficit Disorder with HyperactivityImpulsive BehaviorEtiologyCRITERION VALIDITY030217 neurology & neurosurgery
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Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder

2010

Contains fulltext : 87688.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Although twin and family studies have shown attention-deficit/hyperactivity disorder (ADHD) to be highly heritable, genetic variants influencing the trait at a genome-wide significant level have yet to be identified. As prior genome-wide association studies (GWAS) have not yielded significant results, we conducted a meta-analysis of existing studies to boost statistical power. METHOD: We used data from four projects: a) the Children's Hospital of Philadelphia (CHOP); b) phase I of the International Multicenter ADHD Genetics project (IMAGE); c) phase II of IMAGE (IMAGE II); and d) the Pfizer-funded study from the…

Malemedicine.medical_specialtyCandidate geneAdolescentMedizinSocial SciencesGenome-wide association studySingle-nucleotide polymorphismPolymorphism Single NucleotideArticleGenomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciences0302 clinical medicinePerception and Action [DCN 1]Developmental and Educational PsychologymedicineIMPUTATIONAttention deficit hyperactivity disorderddc:61Humansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersInternational HapMap ProjectPsychiatryChildGenetic Association Studies030304 developmental biologyGenetic associationMental Health [NCEBP 9]0303 health sciencesCOMPONENTSmedicine.disease3. Good healthPREVALENCEPsychiatry and Mental healthAttention Deficit Disorder with HyperactivityMeta-analysisChild PreschoolFemalePsychologyFunctional Neurogenomics [DCN 2]030217 neurology & neurosurgeryImputation (genetics)Clinical psychologyGenome-Wide Association Study
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DSM-IV Combined Type ADHD Shows Familial Association With Sibling Trait Scores

2008

Contains fulltext : 69060.pdf (Publisher’s version ) (Closed access) Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments. Molecular genetic studies have been successful in identifying genetic variants associated with ADHD, particularly with DSM-IV inattentive and combined subtypes. Quantitative trait locus (QTL) approaches to linkage and association mapping have yet to be widely used in ADHD research, although twin studies investigating individual differences suggest that genetic liability for ADHD is continuously distributed throughout the population, u…

Malequantitative geneticsGenetics and epigenetic pathways of disease [NCMLS 6]Genetic Linkageattention deficit hyperactivity disorder (ADHD)GENOMEWIDE SCANMedizin2804 Cellular and Molecular NeuroscienceNeuroinformatics [DCN 3]MULTIPLE-REGRESSION ANALYSIS2738 Psychiatry and Mental Health0302 clinical medicineDIFFICULTIES QUESTIONNAIREDEFICIT-HYPERACTIVITY DISORDERTwins DizygoticPerception and Action [DCN 1]Genetics(clinical)DF analysisAssociation mappingGenetics (clinical)linkage studyGeneticseducation.field_of_studyATTENTION-DEFICIT/HYPERACTIVITY DISORDERDOPAMINE TRANSPORTER GENE10058 Department of Child and Adolescent PsychiatryDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthCHILD-BEHAVIOR CHECKLISTConduct disorderRegression AnalysisFemalemedicine.symptomFunctional Neurogenomics [DCN 2]Clinical psychology2716 Genetics (clinical)Quantitative Trait LociPopulation610 Medicine & healthQuantitative trait locusBiologyImpulsivityMental health [NCEBP 9]behavioral disciplines and activitiesINDIVIDUAL-DIFFERENCESInterviews as TopicGenomic disorders and inherited multi-system disorders [IGMD 3]quantitative trait locus (QTL)03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]mental disordersmedicineHumansSibling RelationsAttention deficit hyperactivity disorderFamilyGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersSiblingeducationTWIN DATAmedicine.diseaseTwin study030227 psychiatryGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with HyperactivityCONDUCT DISORDER030217 neurology & neurosurgeryAmerican Journal of Medical Genetics. Part B: Neuropsychiatric Genetics
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Construct validity of the anxiety sensitivity index-3 in clinical samples

2012

"Using two clinical samples of patients, the presented studies examined the construct validity of the recently revised Anxiety Sensitivity Index-3 (ASI-3). Confirmatory factor analyses established a clear three-factor structure that corresponds to the postulated subdivision of the construct into correlated somatic, social, and cognitive components. Participants with different primary clinical diagnoses differed from each other on the ASI-3 subscales in theoretically meaningful ways. Specifically, the ASI-3 successfully discriminated patients with anxiety disorders from patients with nonanxiety disorders. Moreover, patients with panic disorder or agoraphobia manifested more somatic concerns …

Malevaliditymental disorderPsychometricspsychische StörungStatistics as TopicdiagnosticFear of negative evaluationCognitionddc:150PsychologySomatoform DisordersApplied Psychologyklinische PsychologieconstructSozialwissenschaften SoziologiePsychological Disorders Mental Health Treatment and PreventionKonstruktanxietyAnxiety DisordersValiditätFaktorenanalyseClinical Psychologypsychische Störungen Behandlung und PräventionAnxietyddc:30010700Femaleclinical psychologymedicine.symptomPsychologyPsychological Testing Psychological Counseling Psychological MethodologyClinical psychologyAdultDepartment Psychologiemedicine.medical_specialtyPsychometricsscale constructionAngstfactor analysisTypologieSensitivity and SpecificityDiagnostikmental disordersSkalenkonstruktionmedicineHumansddc:610psychologische Diagnostik und Beratung psychologische MethodenPsychiatrySocial sciences sociology anthropologyErhebungstechniken und Analysetechniken der SozialwissenschaftenAnalysis of VariancePanic disorderDiscriminant validityReproducibility of ResultsConstruct validitymedicine.diseaseMethods and Techniques of Data Collection and Data Analysis Statistical Methods Computer MethodsPsychologieAnxiety sensitivityInstitut für ErnährungswissenschaftASI-3; Angstsensitivitätsindex; Anxiety Sensitivity IndextypologyCognition DisordersFactor Analysis Statistical10200Agoraphobia
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Tom Malmquist: Ilma joka meitä ympäröi

2020

Kirja-arvostelu teoksesta Tom Mamquist: Ilma joka meitä ympäröi (All den luft som omger oss). Suom. Outi Menna. S&S 2020. 347 sivua nonPeerReviewed

Malmquist TomIlma joka meitä ympäröiautofiktiokirja-arvostelut
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Intellectual engagements of accounting academics: The ‘forecasted losses' intervention

2022

This paper explores the social and political potential of accounting scholarship, presenting and discussing an intellectual intervention challenging a legislative reform that significantly affected Spanish industrial relations. In this reform, an accounting artifact (forecasted losses) played an unexpected role and was misrepresented, prompting a sizeable number of scholars to sign two manifestos in 2010 and 2012 against the use of forecasted losses made by the new legislation. As promoters of this manifesto, we perform in this paper a collaborative autoethnography to reflect on the context, events, reactions, and significance of this intervention for both the academic and the industrial re…

ManifestoIndustrial managementInformation Systems and Managementcritical accountingSociology and Political ScienceEconomicsAccounting scholarshipFinanzwirtschaft RechnungswesenaccountingEmpresas-GestiónReflexivitätLegislationContext (language use)AccountingLaw and economicsindustrielle Beziehungenindustrial relationsAccountingPolitical scienceReflexivityddc:330Industrial relationsSpanienRechnungswesenReflexivityISSPbusiness.industryreflexivityWirtschaftUNESCO::CIENCIAS ECONÓMICASIntellectual interventionsIntellectual capitalCritical accountingWork Orientations III - ISSP 2005 (ZA4350 v2.0.0); International Social Survey Programme: Work Orientations IV - ISSP 2015 (ZA6770 v2.1.0) [critical accounting; intellectual interventions; International Social Survey Programme]Financial Planning AccountancySpainCapital (economics)Industrial relationsintellectualDerecho y economíaintellectual interventionsbusinessFinanceIntellektueller
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Die Förderung der Mehrsprachigkeit und der Transkulturalität in der gymnasialen Oberstufe über ein internationales und fremdsprachiges Projekt : Fal…

2010

Tässä laadullisessa tapaustutkimuksessa tutkittiin 2008 kevään aikana suomalaisen Jyväskylän Normaalikoulun lukion ja saksalaisen Görres-Gymnasiumin (Koblenz) toteuttamaa kansainvälistä yhteistyöprojektia. Tavoitteena oli selvittää, kuinka osallistujien transkulturaalinen identiteetti kehittyy sekä toteutuuko monikielisyys tässä kansainvälisessä projektissa. Lisäksi haluttiin selvittää opettajien ja oppilaiden motivaatioita projektiin osallistumiseen sekä kieltenkäyttöä eri tilanteissa. Tutkimus toteutettiin vuonna 2007 projektiin osallistuneiden suomalaisten oppilaiden sekä vuonna 2008 mukana olevien suomalaisten ja saksalaisten opettajien ryhmähaastattelujen ja oppilaiden kyselylomakkeide…

MehrsprachigkeitlukiolaisetJyväskylän Normaalikouluinternationales ProjektSpracherziehungkansainvälisyysGörres-GymnasiummonikielisyysidentiteettiTranskulturalitätLaadullinen tutkimus
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Guido Erwin Kolbenheyer und seine Rezeption des 16. Jahrhunderts am Beispiel der Trilogie des Paracelsus (1917-26).

2016

Der Beitrag fokussiert sich auf die Mystifizierung der paracelsisichen Gedanken, der Figur von Paracelsus selbst sowie des religiösen Diskurses und von manchen Debatten des 16. Jahrhunderst durch Guido Erwin Kolbenheyer. Im Mittelpunkt der Untersuchung steht die Herausbildung des "Andersartigen", der im Kontext einer nationalistischen und fremdenfeindlichen Gesinnug zum Inbegriff einer überlegenen pangermanischen Identität aufgefasst wird.

Mystik des VolkeSettore L-LIN/13 - Letteratura TedescaSuche nach dem Göttlichen.deutsche Identität und FremdenfeindlichkeitMystifizierung der paracelsischen Gedanken im pangermanischen Sinn
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

2013

AM Vicente - Cross-Disorder Group of the Psychiatric Genomics Consortium Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype data from the Psychiatric Genomics Consortium (PGC) for cases and controls in schizophrenia, bipolar disorder, major depressive disorder, autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). We apply univariate and bivariate methods for the estimation of genetic variation within and covariation between disorders. SNPs explained 17-29% of the variance in …

Netherlands Twin Register (NTR)MedizinInheritance PatternsSocial SciencesAUTISM SPECTRUM DISORDERSnosologyheritabilityCOMMON SNPS0302 clinical medicineCrohn DiseaseSCHIZOPHRENIAChildPsychiatric geneticsGenetics & HeredityMAJOR DEPRESSIVE DISORDERRISK0303 health sciencesATTENTION-DEFICIT/HYPERACTIVITY DISORDER120 000 Neuronal CoherenceMental DisordersVariantsBIPOLAR DISORDERASSOCIATIONGenomic disorders and inherited multi-system disorders [DCN PAC - Perception action and control IGMD 3]Psychiatric DisordersCROHNS-DISEASE3. Good healthSchizophreniagenetic association studyMedical geneticsMajor depressive disorderSNPsAdultmedicine.medical_specialtygenetic etiologymedical geneticsDEFICIT HYPERACTIVITY DISORDERBiologyPolymorphism Single Nucleotidebehavioral disciplines and activitiesArticleGenomic disorders and inherited multi-system disorders DCN MP - Plasticity and memory [IGMD 3]HeritabilityGenetic Heterogeneity03 medical and health sciencesPrevalence of mental disordersmental disorders/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyGeneticsmedicineddc:61HumansAttention deficit hyperactivity disorderGenetic Predisposition to Disease[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyDCN PAC - Perception action and control NCEBP 9 - Mental healthddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersBipolar disorderPsychiatry030304 developmental biologyDepressive Disorder MajorGenome HumanGenetic heterogeneitymedicine.diseaseschizophreniaAttention Deficit Disorder with HyperactivityChild Development Disorders PervasivePerturbações do Desenvolvimento Infantil e Saúde Mental030217 neurology & neurosurgeryGenome-Wide Association Study
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Integration, Bewertung und Nutzung heterogener Datenquellen mittels semantischer Werkzeuge

2017

In diesem Artikel stellen wir unsere Forschung in der Integration von Geodaten in einen Semantic Web Kontext in unserem Projekt Semantic GIS vor. Zunächst möchten wir den Zweck und die Vorteile einer Integration und Interpretation von Daten in das Semantic Web beleuchten und anschließend unseren Integrationprozess bestehend aus Datengewin-nung, automatischer Interpretation, Qualitätssicherung und Provenance sowie den Datenzugriff erklären. Um die Anwendung unserer Forschung zu demonstrieren gehen wir auf zwei Anwendungsfälle in unserem Projekt ein: Die Bewertung von OpenStreetMap Daten und die Verbesserung des Katastrophenschutzes mittels semantischem Reasoning. Wir schließen den Artikel mi…

On- tologyR2RMLProvenance Keywords: GeodatenDatenqualitätLinked dataSemantificationOntologieNatural Language processingSDI[INFO] Computer Science [cs]Geospatial dataSemantifikationSemantisches WebProvenance[INFO]Computer Science [cs]Sprachverarbeitung natürlicher SprachenData QualitySemantic web
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