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showing 10 items of 1962 documents
Impact du système endocannabinoïdien sur la physiologie de l'obésité : effets de l'antagonisme des récepteurs CB1 sur le métabolisme glucido-lipidiqu…
2010
The endocannabinoïd system (ECS) is involved in many biological functions such as regulation of energy metabolism. Recently, several studies have shown an association between obesity and ECS overactivity. In addition, specific CB1R antagonists such as Rimonabant (SR141716) improved metabolic parameters in obese patients essentially through inactivation of central CB1R. However, peripheral CB1R inactivation could also contribute to the improvement of these parameters and it is this notion that we have studied. To this purpose, we tested the effects of SR141716 on obese mice in order to establish relationships between the ECS activity and lipid metabolism by looking more specifically to its r…
L'arôme du gin : identification des composés clés et rôle des matières premières
2012
Le texte intégral de cette thèse est confidentiel à durée indéfinie.; Afin d’identifier les composés responsables de l’arôme du gin, une procédure GC-O-MS se basant sur la fréquence de détection a été développée. Elle a permis de déterminer l’intensité odorante des composés volatils. Leur qualité d’odeur a pu être définie par le développement d’une roue des odeurs utilisée pour catégoriser les descripteurs obtenus. Cette approche nous a dans un premier temps permis d’identifier les composés potentiellement importants pour l’arôme du gin. L’origine de ces composés a ensuite été déterminée par l’étude de la fraction volatile de différents « botanicals » appartenant à la recette du gin. Cette …
Harnessing the biodiversity value of Central and Eastern European farmland
2015
A large proportion of European biodiversity today depends on habitat provided by low‐intensity farming practices, yet this resource is declining as European agriculture intensifies. Within the European Union, particularly the central and eastern new member states have retained relatively large areas of species‐rich farmland, but despite increased investment in nature conservation here in recent years, farmland biodiversity trends appear to be worsening. Although the high biodiversity value of Central and Eastern European farmland has long been reported, the amount of research in the international literature focused on farmland biodiversity in this region remains comparatively ti…
Monetary images of celtic people : primitive figures or expressions of a changing society ? : the case of Arveni, Bituriges, Carnutes, Aedui, Lingone…
2011
The study is based on approximately 600 monetary images attributed to Arverni, Bituriges, Carnutes, Aedui, Lingones, Sequani, Parisii, Meldi and Senones. Monetary images form the largest iconographic set provided by the Celts but paradoxically, they are not considered at their fair value in the current research. Indeed, their study is a relatively recent discipline because the Celts left no text allowing their understanding. The different themes of the images relate to religion, society and aristocracy of Iron Age. The multidisciplinary approach (archaeological, literary and artistic) of this work recreates links between monetary images and the celtic society and compleets many areas of stu…
Animaux domestiques et faunes sauvages en territoire Arverne (Vème avant JC - 1er siècle après JC)
2010
This thesis is based upon the study of 160 000 animal bones issued from 23 late iron-age sites excavated in the Auvergne region of central France. The assemblages represent different types of archaeological contexts (farms, aristocratic settlements, agglomerations, oppida, religious/ritual zones and funeral areas) which enable us to study their role in the domestic, craft and sacrificial spheres. The aim of this thesis is to show the implications of animal use within the Gallic society.This thorough study also replaces the data into the chronological context of Gaul between the LaTèneien and Augustian periods, and the geographical territory of the Clermont-Ferrand Basin in the Limagne plain…
The ceramic of Middle Neolithic II between the valleys of the Yonne and the Saône, between 4300 and 3400 BC
2010
The territory between the valleys of the Yonne and the Saône has always been a zone of cultural meeting in particular during the middle Neolithic II, between 4300 and 3400 BC. Since the 1970's, the culture of the Néolithique moyen bourguignon (N.M.B.) has been recognized in this region and its main characteristics were defined during a round table discussion organized in Beffia in 1984 (Pétrequin and Gallay 1984). From criteria based essentially on the ceramic typology, the N.M.B. is then mainly confined within the regions of Burgundy and Franche-Comté.Since 1984, the zone of there culture has been expended in particular to the South and Southwest. Multiple deposits have been discovered sin…
For a semiotic approach of the strategic field of communication
2010
The purpose of this work is to highlight a critical view on communication field and mass consumption, at the crossroad of a double path bridging academic research and professional practice of the author. The semiotics approach, enriched with the light of disciplines like communication sciences, strategy, interaction, anthropology, enables to draft a theory of strategy in the communication field. By considering the latter as a strategic space of actualization of stakes for the actants, ruled by confrontation and rivalry, we bring ourselves the opportunity to consider this field and the phenomenon that are structuring it at its right level. This multiple approach unified by the conceptual and…
"Save the Night" : light footprint, urbanism and territorial governance
2010
Our society maintains a complex relation with night, space-time often outside the diurnal cadences which facilitates the reflection, the imagination, the creation, the listening and the link with the other one, while revealing the segregation, the fear, and thus the restriction. By this research, we put compared to the urban lighting – real light project carrier of a strong symbolism – the socio-cultural, ecological and sanitary costs engendered by the artificial light. The urban lighting generates a geographical interlacing of bright imprints of differentiated scales, which we approach by various modellings, without forbidding us the sensitive analysis. We clarify, at various scales, the g…
The diversion of institution
2010
The diversion of an institution is a notion which was established by the jurisprudence of the « French Court of Cassation », in the early 1990s, about adoption and the phenomena of surrogate mothers.From a chronological point of view, the diversion of institution first broke away from the studies of the doctrine dedicated to the abuse of rights , and was first used by the jurisprudence in labour law, before being dedicated to family rights. Because it deals with diversion of the finality of a legal system institution, it is often confused with the abuse of rights, the abuse of power, and fraud of the law or similar. Nevertheless, common points between the diversion of institution and other …
On students' understanding of Riemann sums of integrals of functions of two variables
2018
International audience; APOS (Action-Process-Object-Schema) Theory is used to pose and test a conjecture of mental constructions that may be used to understand the relation between integrals of two variable functions over rectangles and corresponding Riemann sums. Interviews with ten students who had just finished a multivariable calculus course showed that the conjectured mental constructions are necessary.