Search results for "korona"
showing 10 items of 32 documents
Serological Follow-Up Study Indicates High Seasonal Coronavirus Infection and Reinfection Rates in Early Childhood
2022
Seasonal human coronaviruses (HCoVs) cause respiratory infections, especially in children. Currently, the knowledge on early childhood seasonal coronavirus infections and the duration of antibody levels following the first infections is limited. Here we analyzed serological follow-up samples to estimate the rate of primary infection and reinfection(s) caused by seasonal coronaviruses in early childhood. Serum specimens were collected from 140 children at ages of 13, 24, and 36 months (1, 2, and 3 years), and IgG antibody levels against recombinant HCoV nucleoproteins (N) were measured by enzyme immunoassay (EIA). Altogether, 84% (118/140) of the children were seropositive for at least one s…
Cabbage and fermented vegetables: from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19
2021
International audience; Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1 R) axis associated with oxidative stress. This leads to insulin resistance …
Computational approach to design of aptamers to the receptor binding domain of SARS-CoV-2
2021
The aim of the research. In this work, in silico selection of DNA-aptamers to the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein was performed using molecular modeling methods. Material and methods. A new computational approach to aptamer in silico selection is based on a cycle of simulations, including the stages of molecular modeling, molecular docking, molecular dynamic simulations, and quantum chemical calculations. To verify the obtained calculated results flow cytometry, fluorescence polarization, and small-angle X-ray scattering methods were applied. Results. An initial library consisted of 256 16-mer oligonucleotides was modeled. Based on molecular docking results, th…
Zvaigžņotā Debess: 2016/17, Ziema (234)
2016
Contents: “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: A.Balklavs. New Possibilities in Search of Cosmic Gravitational Waves (abridged) ; E.Mūkins. «Venus-9» and «Venus-10» Scientific Accomplishment (abridged) ; DEVELOPMENTS in SCIENCE: K.Schwartz. The Unknown Solar Corona ; DISCOVERIES: I.Pundure. Gaia Has Obtained Billion-Star 3D Map ; SPACE RESEARCH and EXPLORATION: J.Jaunbergs. Tar Lakes of Titan ; R.Misa. A Step Closer to Stars ; CONFERENCES and MEETINGS: J.Balodis. Copernicus Is Becoming an Impressive Business ; K.Bērziņš. Conference of Young European Radioastronomers at the Latvian Centre in Germany ; FLASHBACK: A.Alksnis. Short Trips and Faraway Journeys (concluded) ; For SCHOOL YOUTH: D.Bo…
The Connection Between the Covid-19 Pandemic Anxiety and Resilience
2022
Bakalaura darba mērķis bija noskaidrot, vai pastāv saistība starp Covid-19 pandēmijas trauksmi un dzīvesspēku. Pētījuma izlasi veido 128 respondenti vecumā no 18 līdz 98 gadiem. Pētījumā tika izmantotas 2 pētījuma metodes - Dzīvesspēka aptauja pieaugušajiem (RSC – Resilience Scale of Adults (Fribor et al., 2005), kuru latviešu valodā ir adaptējusi Līga Sovere 2010. gadā un Koronavīrusa trauksmes skala (Coronavirus Anxiety Scale (CAS); Lee, 2020). Latviešu valodā adaptāciju veikusi Lida Maslinovska maģistra darba izstrādes ietvaros 2021. gadā. Pētījuma empīriskajā daļā veikts korelatīvs pētījums, izmantojot Spīrmena korelācijas metodi. Rezultāti norāda, ka Covid-19 pandēmijas trauksmei nav s…
Conditions and strategies to meet the challenges imposed by the COVID-19-related visiting restrictions in the intensive care unit: A Scandinavian cro…
2022
ObjectivesTo examine conditions and strategies to meet the challenges imposed by the coronavirus disease 2019 (COVID-19)-related visiting restrictions in Scandinavian intensive care units.Research methodology/designA cross-sectional survey.SettingAdult intensive care units in Denmark, Norway and Sweden.Main outcome measuresLikert scale responses and free-text comments within six areas: capacity and staffing, visiting policies and access to the unit, information and conferences with relatives, written information, children as relatives and follow-up initiatives.ResultsThe overall response rate was 53% (74/140 participating units). All intensive care units had planned for capacity extensions;…
Adoption of a COVID-19 Contact Tracing App Among Older Internet Users in Finland
2022
The outbreak of the COVID-19 pandemic created an unequal need for limiting physical contacts and tracing possible exposures to a novel coronavirus. Smartphone-based contact tracing applications (CTAs) were presented as a vehicle for stopping virus transmission chains and supporting the work of contact tracing teams. In this study, older adults’ adoption of a CTA was studied using socioeconomic background factors, satisfaction with health, and the measure of digital activity as predictors. The data were drawn from a larger questionnaire survey targeted at older internet users. A subsample of older Finnish internet users (N = 723) was analyzed using a logistic regression model. Results showed…
A Cross-Country Examination on the Fear of COVID-19 and the Sense of Loneliness during the First Wave of COVID-19 Outbreak
2021
The aim of the current study is to examine gender, age. and cross-country differences in fear of COVID-19 and sense of loneliness during the lockdown, by comparing people from those countries with a high rate of infections and deaths (e.g., Spain and Italy) and from countries with a mild spread of infection (e.g., Croatia, Serbia, Slovakia, Slovenia, and Bosnia and Herzegovina). A total of 3876 participants (63% female) completed an online survey on “Everyday life practices in COVID-19 time” in April 2020, including measures of fear of COVID-19 and loneliness. Males and females of all age groups in countries suffering from the powerful impact of the COVID-19 pandemic reported greater fear o…
Maintaining everyday life praxis in the time of COVID-19 pandemic measures (ELP-COVID-19 survey)
2020
Abstract Background The extreme social circumstances caused by declared COVID-19 pandemic deeply intervene people’s everyday life and should not be neglected but seen through the view of social reality pinpointing the ‘ordinary’ people. In this article, authors explored basic segments of everyday and their subjective perception to what extent sleeping habits, physical inactivity, physical activity, nutritional habits and smoking have changed. Methods The online survey was conducted in nine European countries (Bosnia and Herzegovina, Croatia, Greece, Kosovo*, Italy, Serbia, Slovakia, Slovenia and Spain) in 4108 participants, aged 15–82 years. The survey took place 30–40 days after World Heal…
The differences of Slovenian and Italian daily practices experienced in the first wave of covid-19 pandemic
2022
Abstract Background The COVID-19 pandemic situation with the lockdown of public life caused serious changes in people's everyday practices. The study evaluates the differences between Slovenia and Italy in health-related everyday practices induced by the restrictive measures during first wave of the COVID-19 pandemic. Methods The cross-sectional cohort study examined changes through an online survey conducted in nine European countries from April 15–28, 2020. The survey included questions from a simple activity inventory questionnaire (SIMPAQ), the European Health Interview Survey, and some other questions. To compare difference in changes between European countries we examined Italy with s…