Search results for "laser"

showing 10 items of 3161 documents

Apoptosis of male germ-line stem cells after laser ablation of their niche.

2007

AbstractMale germ-line stem cells (GSCs) and their niche-the apical cells or hub cells-display a unique feature at the apices of insect testicular follicles. In the locust, Locusta migratoria, the niche consists of only one large apical cell surrounded by about 60 GSCs. The apical cell can be readily identified in the intact follicle. Using laser ablation it is feasible to destroy the apical cell exclusively without injuring neighboring GSCs or any other cells. The most immediate effect on GSCs is the loss of their structural polarity. Beginning about 3 h after laser treatment chromatin starts to clump and condense in individual GSCs, and some show the first signs of cellular breakdown. The…

Maleendocrine systemLocusta migratoriaMitosisApoptosisApical cellBiologyGermlineFollicleAnimalsStem Cell NicheMitosisMedicine(all)TUNEL assayStem CellsfungiCell PolarityGeneral MedicineAnatomyCell BiologyChromatinCell biologyGerm CellsApoptosisLaser TherapyStem cellDevelopmental BiologyStem cell research
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Periodontal Treatment with an Er:YAG Laser or Scaling and Root Planing. A 2-Year Follow-Up Split-Mouth Study

2003

Non-surgical periodontal treatment with an Er:YAG laser has been shown to result in significant clinical attachment level gain; however, clinical results have not been established on a long-term basis following Er:YAG laser treatment. Therefore, the aim of the present study was to present the 2-year results following non-surgical periodontal treatment with an Er:YAG laser or scaling and root planing.Twenty patients with moderate to advanced periodontal destruction were treated under local anesthesia, and the quadrants were randomly allocated in a split-mouth design to either 1) Er:YAG laser (ERL) using an energy level of 160 mJ/pulse and 10 Hz, or 2) scaling and root planing (SRP) using han…

Malegenetic structuresGingival and periodontal pocketMatched-Pair AnalysisBleeding on probingDental PlaqueDentistryRoot PlaningScaling and root planingPeriodontal Attachment LossmedicineHumansPeriodontal PocketGingival RecessionYttriumPeriodontitisGingival recessionPeriodontitisBacteriabusiness.industryDental Plaque Indexmedicine.diseaseDental Plaque IndexTreatment OutcomeClinical attachment lossDental ScalingPeriodonticsAluminum SilicatesFemaleLaser TherapyPeriodontal Indexmedicine.symptomGingival HemorrhagebusinessEr:YAG laserErbiumFollow-Up StudiesJournal of Periodontology
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Perioperative pupil size in low-energy femtosecond laser-assisted cataract surgery

2020

Purpose To assess potential changes in pupil size during femtosecond laser-assisted cataract surgery (FLACS) using a low-energy laser system. Methods The pupil sizes of eyes undergoing FLACS were measured using the Ziemer LDV Z8 by extracting images from the laser software after each of the following steps: application of suction, lens fragmentation, and capsulotomy. Furthermore, the pupil diameters were measured based on preoperative surgical microscope images and after releasing the suction. Paired t-test and the two one-sided tests (TOST) procedure were used for statistical analyses. The horizontal and vertical pupil diameters were compared in each of the steps with preoperative values.…

Malegenetic structuresProstaglandinmedicine.medical_treatmentBiochemistryPupillaw.inventionCornea0302 clinical medicinelawCorneaMedicine and Health SciencesLipid HormonesAged 80 and overEye LensMultidisciplinaryQOphthalmic ProceduresRCataract SurgeryMiddle Agedmedicine.anatomical_structureOptical EquipmentCapsulotomyEngineering and TechnologyMedicineFemaleLaser TherapyAnatomyResearch Articlemedicine.medical_specialtySuctionOcular AnatomyScienceEquipmentSurgical and Invasive Medical ProceduresCataract Extraction03 medical and health sciencesOcular SystemOphthalmologymedicineHumansPerioperative PeriodAgedRetrospective Studiesbusiness.industryLasersBiology and Life SciencesPupilPerioperativeCataract surgeryLaserHormoneseye diseasesConfidence interval030221 ophthalmology & optometryEyessense organsbusinessHead030217 neurology & neurosurgeryPLOS ONE
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Effect of laser therapy on expression of angio- and fibrogenic factors, and cytokine concentrations during the healing process of human pressure ulce…

2018

Objective: To evaluate the effect of laser irradiation at different wavelengths on the expression of selected growth factors and inflammatory mediators at particular stages of the wound healing process. Methods: Sixty-seven patients were recruited, treated, and analyzed (group A - 940 nm: 17 patients; group B - 808 nm: 18 patients; group C - 658 nm: 16 patients; group D - sham therapy: 17 patients). Patients received a basic treatment, including repositioning and mobilization, air pressure mattress and bed support surfaces, wound cleansing and drug therapy. Additionally, patients received laser therapy once a day, 5 times a week for 1 month in use of a semiconductor lasers (GaAIAs) which em…

Malemedicine.medical_specialtyAngiogenesismedicine.medical_treatmentUrologyInflammationStimulationMONOPHASIC PULSED CURRENTCLINICAL-TRIALpressure ulcers030207 dermatology & venereal diseases03 medical and health scienceslaser therapy0302 clinical medicinegrowth factorsMedicine and Health SciencesmedicineHumans030212 general & internal medicineLow-Level Light TherapyFibroblastInterleukin 6AgedAged 80 and overPressure UlcerWound Healingbiologybusiness.industryInterleukinGeneral MedicineinterleukinsCytokinemedicine.anatomical_structurebiology.proteinCytokinesFemalemedicine.symptomWound healingbusinessResearch PaperInternational Journal of Medical Sciences
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Ablative fractional laser-assisted photodynamic therapy for lentigo maligna: a prospective pilot study.

2019

Background Lentigo maligna (LM) is an in‐situ form of melanoma carrying a risk of progression to invasive lentigo maligna melanoma (LMM). LM poses a clinical challenge, with subclinical extension and high recurrence rates after incomplete surgery. Alternative treatment methods have been investigated with varying results. Photodynamic therapy (PDT) with methylaminolaevulinate (MAL) has already proved promising in this respect. Objectives To investigate the efficacy of ablative fractional laser (AFL)‐assisted PDT with 5‐aminolaevulinic acid nanoemulsion (BF‐200 ALA) for treating LM. Methods In this non‐sponsored, prospective pilot study ten histologically verified LMs were treated with AFL‐as…

Malemedicine.medical_specialtyBF-200 ALASkin NeoplasmsBiolääketieteet - Biomedicinemedicine.medical_treatmentFractional laserPhotodynamic therapyPilot ProjectsDermatologyLentigo malignalaserhoitoHutchinson's Melanotic Freckle030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineablative fractional laser5-aminolaevulinic acid nanoemulsionAblative casemedicineHumansmelanoomaProspective StudiesLentigo maligna melanomaSubclinical infectionAgedAged 80 and overbusiness.industryRopivacaineMelanomaSisätaudit - Internal medicineAminolevulinic AcidMiddle Agedmedicine.diseaseCombined Modality Therapy3. Good healthInfectious Diseasesphotodynamic therapyfotodynaaminen hoitoPhotochemotherapy030220 oncology & carcinogenesisFemaleRadiologyLaser Therapylentigo malignabusinessmedicine.drugJournal of the European Academy of Dermatology and Venereology : JEADVReferences
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Endoscopic enhancement of the healing of high-risk colon anastomoses by low-power helium-neon laser. An experimental study.

1992

Recent studies suggest that helium-neon (He-Ne) lasers at low energy can enhance wound healing in intestinal anastomoses. In this experimental study, we tested the strength and collagen concentration of high-risk anastomoses of the rat colon after endoscopic irradiation by helium-neon laser. Our results show that repeated helium-neon laser irradiation (1.9 J/cm 2)increases the bursting strength of the anastomoses by almost 100% on the fourth postoperative day. This effect is not observed by increasing the radiation dose (6.4 J/cm 2).Differences in collagen (hydroxyproline) concentration did not reach statistical significance.

Malemedicine.medical_specialtyColonAnastomosisRadiation Dosagelaw.inventionHydroxyprolinechemistry.chemical_compoundSurgical anastomosislawRisk FactorsTensile StrengthSurgical Wound DehiscencemedicineAnimalsIrradiationWound Healingbusiness.industryAnastomosis SurgicalGastroenterologyRats Inbred StrainsGeneral MedicineColonoscopyLaserSurgeryRatschemistryHelium/neon laserCollagenLaser TherapyWound healingNuclear medicinebusinessBursting strengthDiseases of the colon and rectum
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: Med Oral Patol Oral Cir Bucal

2017

Background Oral cancer is a public health issue worldwide. Oral potentially malignant disorders (OMPDs) are lesions of the oral mucosa that are predisposed to malignant transformation. The mainstay of OMPDs treatment around the world is now the carbon dioxide (CO2) laser but the reported recurrence and malignant transformation rates vary widely in the literature. We aimed to estimate the recurrence and the malignant transformation rates of OPMDs treated with CO2 laser at the University Hospital of Bordeaux, in France, from 2010 to 2014, and to identify associated factors with recurrence or malignant transformation. Material and Methods We conducted a retrospective study in patients with a m…

Malemedicine.medical_specialtyDiseaseMalignant transformationIDLIC03 medical and health sciences0302 clinical medicinemedicineHumansOral mucosaGeneral DentistryAgedRetrospective StudiesAged 80 and overMouthCo2 laserbusiness.industryResearchCancerRetrospective cohort study030206 dentistryHyperplasiaCarbon DioxideMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDermatology3. Good healthmedicine.anatomical_structureCell Transformation NeoplasticOtorhinolaryngologyDysplasia030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICAS[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieSurgeryFemaleMouth NeoplasmsLaser TherapyNeoplasm Recurrence LocalOral SurgerybusinessPrecancerous ConditionsMedicina oral, patologia oral y cirugia bucal
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Initial Experience with Radical Prostatectomy Following Holmium Laser Enucleation of the Prostate

2021

Background: Although an increasing number of prostate cancer (PCa) patients received holmium laser enucleation of the prostate (HoLEP) previously for benign prostatic obstruction (BPO), there is still no evidence regarding the outcomes of radical prostatectomy (RP) in this setting. Objective: To assess functional and oncological results of RP in PCa patients who received HoLEP for BPO previously in a contemporary multi-institutional cohort. Design, setting, and participants: A total of 95 patients who underwent RP between 2011 and 2019 and had a history of HoLEP were identified in two institutions. Functional as well as oncological follow-up was prospectively assessed and retrospectively an…

Malemedicine.medical_specialtyHolmium laser enucleation of the prostate; Localized prostate cancer; Patient-reported outcomes; Radical prostatectomy; Urinary continenceUrologymedicine.medical_treatmentEnucleation030232 urology & nephrologyUrologyProstatic HyperplasiaUrinary incontinenceLasers Solid-State03 medical and health sciencesBladder outlet obstructionProstate cancerHolmium0302 clinical medicineErectile DysfunctionmedicineHumansRetrospective StudiesProstatectomyLocalized prostate cancerPatient-reported outcomesProstatectomybusiness.industryHazard ratioProstateUrinary continenceOdds ratiomedicine.diseaseRadical prostatectomyHolmium laser enucleation of the prostate030220 oncology & carcinogenesisPropensity score matchingmedicine.symptombusiness
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On the number of measurement sites required to assess regional cerebral blood flow by laser-Doppler scanning during cerebral ischemia and reperfusion.

2001

The aim of this study was to determine whether the number of measurement sites affected the precision of regional cerebral blood flow (CBF) assessment by Laser-Doppler (LD). A simulation study was applied based on data obtained by scanning the cortex in 25 rats during baseline conditions, 15 min global cerebral ischemia and reperfusion. Random samples were repeatedly collected from 1 to 100 locations and deviations from the median of the entire CBF data pool (800 locations) were determined. Single location CBF measurements missed the true median by 24.8+/-2.2 LD-units (baseline conditions, n=100 simulations, mean+/-SEM), 2.7+/-0.6 LD-units (ischemia), and 31.9+/-2.4 LD-units (30th min reper…

Malemedicine.medical_specialtyIschemiaHemodynamicsBrain IschemiaInternal medicinemedicineLaser-Doppler FlowmetryAnimalsRats WistarObserver VariationMeasurement methodbusiness.industryGeneral NeuroscienceReproducibility of ResultsBlood flowLaser Doppler velocimetrymedicine.diseaseRatsCerebral blood flowAnesthesiaCerebrovascular CirculationReperfusion InjuryCardiologybusinessObserver variationJournal of neuroscience methods
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Endoluminal sclerosis with diode laser in the treatment of orofacial venous malformations

2012

Introduction: The appearance of vascular anomalies in the orofacial area is a common condition, which represents about 50% of these malformations. Traditional treatment approach, such as surgery and chemical sclerosis has been given way to a few less-invasive options, as the use of the 810nm diode laser to induce the sclerosis of the venous malformation by intralesional photocoagulation. Objectives: The objective of this study was to determine the efficacy of the diode laser in the intralesional treatment of the orofacial venous malformations (OFVM), describing the recommended surgical approach, as well as to report the main associated complications. Patients and Methods: 10 cases of OFVM, …

Malemedicine.medical_specialtyLàsers en odontologiaAdolescentmedicine.medical_treatmentOdontologíaMalalties vascularslaw.inventionArteriovenous MalformationsLesionYoung AdultOral surgerylawSclerotherapymedicineSclerotherapyHumansLocal anesthesiaGeneral DentistryVascular diseasesRetrospective StudiesMouthSurgical approachCirurgia oralbusiness.industryRetrospective cohort studyContinuous mode:CIENCIAS MÉDICAS [UNESCO]Lasermedicine.diseaseCiencias de la saludSurgeryOtorhinolaryngologyLasers in dentistryFaceUNESCO::CIENCIAS MÉDICASFemaleResearch-ArticleSurgeryLasers SemiconductorOral Surgerymedicine.symptomVenous malformationbusiness
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