Search results for "lasi"
showing 10 items of 1298 documents
National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological st…
2011
Summary Background Data for trends in blood pressure are needed to understand the effects of its dietary, lifestyle, and pharmacological determinants; set intervention priorities; and evaluate national programmes. However, few worldwide analyses of trends in blood pressure have been done. We estimated worldwide trends in population mean systolic blood pressure (SBP). Methods We estimated trends and their uncertainties in mean SBP for adults 25 years and older in 199 countries and territories. We obtained data from published and unpublished health examination surveys and epidemiological studies (786 country-years and 5·4 million participants). For each sex, we used a Bayesian hierarchical mo…
Treatment of esophageal cancer in inoperable elderly patients: our experience
2009
The esophagus carcinoma has an incidence rate of 3–4 new cases per 100,000 inhabitants, per year, with a male/female ratio of 3:1 and with a low incidence between the VI–VII decade of life. In Italy, the incidence rate equals 2,000 new cases/year with a mortality rate of 3–5/100,000 inhabitants.
Colorectal cancer survival in the USA and Europe: a CONCORD high-resolution study
2013
Journal Article; OBJECTIVES: To assess the extent to which stage at diagnosis and adherence to treatment guidelines may explain the persistent differences in colorectal cancer survival between the USA and Europe. DESIGN: A high-resolution study using detailed clinical data on Dukes' stage, diagnostic procedures, treatment and follow-up, collected directly from medical records by trained abstractors under a single protocol, with standardised quality control and central statistical analysis. SETTING AND PARTICIPANTS: 21 population-based registries in seven US states and nine European countries provided data for random samples comprising 12 523 adults (15-99 years) diagnosed with colorectal ca…
Peripheral ossifying fibroma:a 20-year retrospective study with focus on clinical and morphological features
2022
Peripheral Ossifying Fibroma (POF) is a reactive hyperplastic lesion that exclusively occurs in the gingiva and is characterized by the deposition of dystrophic calcification, cementum-like tissue, and immature and mature bone within the connective tissue. The objective of the present study was to perform a retrospective analysis of clinicopathologic features of POF. Clinical and histopathological data were obtained from biopsy records and histopathological reports from a Brazilian reference service in Oral Pathology (1999 - 2020). Morphological analysis was performed to evaluate features related to the mesenchymal component, inflammatory infiltrate, ulceration, and mineralized tissue. A to…
Amlodipine-induced gingival hyperplasia
2006
Drug-induced gingival hyperplasia is a serious concern both for the patient and the clinician. A 45 year-old Caucasian male patient with hypertension, who received amlodipine (10 mg/day, single dose orally) for two months, sought medical attention because of the new-onset gingival enlargement. On clinical examination a generalized and firm overgrowth of the gingival throughout the maxilla and the mandible were evident. The lack of gingival inflammation and purulent discharge were other features of the clinical scenario. Histological assessment of the biopsy specimen revealed the hyperplasia of connective tissue, epithelial acanthosis, and elongated rete ridges along with few inflammatory ce…
A novel mutation in FGFR-3 disrupts a putative N-glycosylation site and results in hypochondroplasia
2000
Winterpacht, Andreas, Katja Hilbert, Christiane Stelzer, Thorsten Schweikardt, Heinz Decker, Hugo Segerer, Jürgen Spranger, and Bernhard Zabel. A novel mutation in FGFR-3 disrupts a putative N-glycosylation site and results in hypochondroplasia. Physiol. Genomics 2: 9–12, 2000.—Fibroblast growth factor receptor 3 (FGFR3) is a glycoprotein that belongs to the family of tyrosine kinase receptors. Specific mutations in the FGFR3 gene are associated with autosomal dominant human skeletal disorders such as hypochondroplasia, achondroplasia, and thanatophoric dysplasia. Hypochondroplasia (HCH), the mildest form of this group of short-limbed dwarfism disorders, results in ∼60% of cases from a mut…
Un Bonaparte en el trono de las Españas y de las Indias. Iconografía de José Napoleón I
2011
En 1808 es proclamado en Madrid rey de las Españas y de las Indias José I, hermano de Napoleón Bonaparte. Su llegada al trono, apoyado por las bayonetas francesas tras la renuncia obligada de los borbones en Bayona, provocará el estallido de la guerra en la península y la desobediencia activa de las colonias americanas. Su reinado, que se prolongará seis años, será una constante guerra de imágenes entre los artistas y apologistas a su servicio, y aquellos que permanecen fieles a Fernando VII y usan la sátira y la caricatura para desprestigiar al monarca impuesto. Pinturas, dibujos y grabados realizados estos años nos muestran el feroz combate visual entre unos y otros, y el fracaso de un re…
Multiple granular cell tumors with metachronous occurrence in tongue and vulva. Clinicopathological and immunohistochemical study
2014
Granular cell tumor (GCT) usually occurs as a single tumor, although sometimes multiple lesions can occur. In present report we analyze the clinicopathological and immunohistochemical features of a multiple GCT involving the tongue of a 14-year-old girl, with no other abnormalities, with a metachronous occurrence of a second GCT in vulva, after a period of 10 years. Both tumors revealed S-100, vimentin and CD57 positivity. In addition, over expression of calretinin was observed in tumor cells located in the vicinity of pseudoepitheliomatous hyperplasia (PEH) of the tongue. Tumor vasculature situated close to the PEH showed marked CD105 reactivity, data not described so far, suggesting an in…
Group analysis and similarity solutions of the compressible boundary layer equations
1989
In this paper the application of Lie's methods to the equations of the laminar boundary layer is discussed. The momentum and energy equations in Prandtl's form are considered for a steady, viscous, compressible laminar flow with non zero pressure gradient, variable viscosity and thermal conductivity. Group analysis yields similarity solutions for given pressure distributions and particular values of the invariance group parameters (group classification). Crocco's transformation is obtained for the infinite-dimensional group of the Lie's algebra admitted by the equations.
Genitale Blutungen in der Menopause mit besonderer Ber�cksichtigung der glandul�r-cystischen Hyperplasie
1950
Bei 245 Fallen mit Blutungen nach mindestens 3jahriger Menopause handelt es sich in 95% um eine uterine Blutung. Davon war in 43,75% ein maligner Tumor die Ursache. In 9,6% war das histologische Substrat eine glandular-cystische Schleimhaut, deren histologisches Bild nicht gegen das des diffusen Korpusadenoms abzugrenzen ist. Es wird daher diskutiert, ob diese Bilder immer die Folge eines Follikelhormonuberschusses seien, ob es sich nicht vielmehr in der spaten Menopause in einem Teil der Falle um einen gutartigen autonomen Tumor handelt. Bei 9 Fallen mit glandular-cystischer Schleimhaut nach Hormontherapie und Granulosazelltumor (1 Fall) fiel die nur schwache Cystenbildung im Gegensatz zu …