Search results for "layer"

Interrelationship Among Morphology, Metabolism, and Proliferation of Tumor Cells in Monolayer and Spheroid Culture

1989

Previous investigations have indicated a positive correlation between the proliferative and metabolic activities of tumor cells in monolayer culture (Freyer et al., 1984; Freyer and Sutherland, 1985; Walenta and Mueller-Klieser, 1987). On the other hand, no difference in the local oxygen consumption has been found between highly proliferating outer cell areas and non-proliferating inner cellular regions in multicellular tumor spheroids (Mueller-Klieser, 1984, 1987). Therefore, the interrelationship among metabolism, proliferation, and cellular morphology was investigated systematically in tumor cells both in monolayer and spheroid culture.

Pancreatic islets from non-heart beating donor pig: Two-layer preservation method in an in vitro porcine model

2011

Purpose Pancreata from non-heart beating donors could represent an unlimited source of islets if their cell viability can be efficiently preserved during the time necessary to process the organs by the use of a better solution of preservation compared to the classic University of Wisconsin solution. The aim of this study was to determine whether it is possible to obtain functioning “alive islets” from non-heart-beating donors by comparing, on a porcine model, the classic “UW ice-store” method with a two-layer cold storage method (TLM) using oxygenated Perfluorocarbons (PFC) and UW. Methods Whole pancreata were harvested from 20 NHBDs female pigs with similar characteristics and preserved fo…

PLAYING-RELATED MUSCULOSKELETAL DISORDERS IN WOODWIND, BRASS AND PERCUSSION PLAYERS: A REVIEW

2010

Performing Arts Medicine is a broad field that includes the study of medical conditions and injuries incurred by dancers, instrument musicians and vocalists. Musicians' playing-related health problems have focused more and more the interest of scientists, researchers, physicians, physiotherapists and, in generally, of health care professionals during the last decades. The most relevant Performing Arts Medicine's literature of approximately the past twenty years has been summarized. Special attention has been given to studies concerning playing-related musculoskeletal conditions of musicians. Overuse syndrome is the most reported diagnosis among instrumental musicians suffering from playing-…

Effects of ultrasonically activated irrigants with or without surfactant on smear layer removal after post space preparation

2012

The aim of this study was to compare the effects of different NaOCl and EDTA formulations with/without ultrasonic use on smear layer removal and root canal surface characteristics after post space preparation. Study design: After post space preparations, forty-six teeth were subjected to different post space irrigation regimes; G1, 17% EDTA; G2, 17% EDTA+Ultrasonic activation; G3, EDTA-T; G4, EDTA-T+Ultrasonic activation; G5, NaOCl; G6, NaOCl+Ultrasonic activation. Specimens were examined under scanning electron microscope and scored for debris and smear layer removal and dentinal tubule opening and statistically analyzed with Kruskal Wallis and Dunn's test. Significance value was set at p<…

Neural Networks Ensemble for Cyclosporine Concentration Monitoring

2001

This paper proposes the use of neural networks ensemble for predicting the cyclosporine A (CyA)concen tration in kidney transplant patients. In order to optimize clinical outcomes and to reduce the cost associated with patient care, accurate prediction of CyA concentrations is the main objective of therapeutic drug monitoring. Thirty-two renal allograft patients and different factors (age, weight, gender, creatinine and post-transplantation days, together with past dosages and concentrations)w ere studied to obtain the best models. Three kinds of networks (multilayer perceptron, FIR network, Elman recurrent network) and the formation of neural-network ensembles were used. The FIR network, y…

Canal transportation caused by a new instrumentation technique and three standard techniques

1996

The ability of three different enlarging techniques (balanced force concept, step-back, and recapitulation) and a prototype system to maintain the original canal path during root canal preparation were compared, in vitro, with a theoretical ideally prepared root canal. Measurements were made at the concave and convex sides of the canal at four different levels (1, 4, 5, and 7 mm from apical, respectively). Simulated root canals embedded in clear casting resin and an enlarging computer-supported device were used for this study. The results showed that none of the enlarging techniques used in this study was able to prepare a canal ideally. The prototype system, at level 1, showed an ideal amo…

Isolation and characterization of pluripotent cells from the subendocardial layer of human hearts from chronic heart failure patients

2008

Radiation transmission data for radionuclides and materials relevant to brachytherapy facility shielding

2008

To address the limited availability of radiation shielding data for brachytherapy as well as some disparity in existing data, Monte Carlo simulation was used to generate radiation transmission data for 60Co, 137CS, 198Au, 192Ir 169Yb, 170Tm, 131Cs, 125I, and 103pd photons through concrete, stainless steel, lead, as well as lead glass and baryte concrete. Results accounting for the oblique incidence of radiation to the barrier, spectral variation with barrier thickness, and broad beam conditions in a realistic geometry are compared to corresponding data in the literature in terms of the half value layer (HVL) and tenth value layer (TVL) indices. It is also shown that radiation shielding calc…

Effectiveness of Nd:YAG Laser on the elimination of debris and Smear Layer : a comparative study with two different irrigation solution: Edta and qmi…

2018

Background The aim of this study was to evaluate the effectiveness in dentin debris and smear layer removal from root canal walls using EDTA and QMix® alone and also activated with Nd:YAG laser. Material and Methods 50 single-rooted teeth were instrumented and divided in 5 groups according to irrigation protocol: 17% EDTA, QMix®, Nd:YAG laser alone, and combination of 17% EDTA - Nd:YAG laser and QMix® - Nd:YAG laser. Samples were evaluated using SEM. Statistical analysis was done using Chi-Square Fisher exact test and McNemar test. Results Dentinal debris analysis showed statistically significant differences when comparing 17% EDTA vs Laser and Laser vs QMix® in combination with Laser at th…

Broad-beam transmission data for new brachytherapy sources, Tm-170 and Yb-169

2005

The characteristics of the radionuclides (170)Tm and (169)Yb are highly interesting for their use as high dose-rate brachytherapy sources. The introduction of brachytherapy equipment containing these sources will lead to smaller required thicknesses of the materials used in radiation protection barriers compared with the use of conventional sources such as (192)Ir and (137)Cs. The purpose of this study is to determine the required thicknesses of protection material for the design of the protecting walls. Using the Monte Carlo method, transmission data were derived for broad-beam geometries through lead and concrete barriers, from which the first half value layer and tenth value layer are ob…