Search results for "lcsh:T"

showing 10 items of 2832 documents

La necesaria renovación de la formación del profesorado para una educación cientifica de calidad.

2007

Se analiza en primer lugar, a la luz de la investigación, cuáles han sido los progresos realizados en el campo de la formación del profesorado de ciencias durante las dos últimas décadas así como las dificultades encontradas. Tomando en consideración los resultados de dicho análisis, se intentan fundamentar propuestas de renovación de la formación del profesorado para el logro de una educación científica de calidad que responda a las nuevas necesidades sociales.

lcsh:LC8-6691lcsh:Theory and practice of educationlcsh:Special aspects of educationlcsh:LB5-3640Tecné, Episteme y Didaxis
researchProduct

Reflexiones sobre la enseñanza de la geometría en primaria y secundaria

2013

En este artículo presentamos
 introducciones a algunos modelos didácticos
 centrales de la enseñanza de la geometría en los
 diferentes niveles educativos desde infantil hasta la
 universidad. En primer lugar introducimos el modelo
 de Van Hiele, que es el marco más efectivo para organizar
 la enseñanza de la geometría en los diferentes
 niveles educativos. Nos centramos en uno de sus
 componentes, las fases de aprendizaje, que sugiere
 cómo organizar los contenidos de los temas de enseñanza
 de las matemáticas escolares. Luego, prestamos
 atención al modelo de Vinner de aprendizaje de conceptos
 matemáticos con un fuerte apoyo grá…

lcsh:LC8-6691lcsh:Theory and practice of educationlcsh:Special aspects of educationlcsh:LB5-3640Tecné, Episteme y Didaxis
researchProduct

Investigación e innovación en la enseñanza de las ciencias. Necesidad de una mayor vinculación

2013

En este artículo se analizan las vinculaciones investigación/innovación en la enseñanza de las ciencias, mostrando resultados que ponen de manifiesto que esta relación no es en la práctica tan estrecha como sería conveniente debido principalmente a dos causas: por un lado, los docentes prestan una escasa atención a la investigación en didáctica de las ciencias e incluso desconocen las revistas especializadas en las que dicha investigación se publica; y, por otro, los investigadores ven la innovación como una mera aplicación de la investigación. Como resultado de estos análisis, se avanza en algunas propuestas para que la investigación contribuya más eficazmente a una mejora generalizada de …

lcsh:LC8-6691lcsh:Theory and practice of educationlcsh:Special aspects of educationlcsh:LB5-3640Tecné, Episteme y Didaxis: TED
researchProduct

Towards a framework for New Service Development Practices

2017

Different frameworks for New Service Development (NSD) practices have been suggested by prior conceptual research. We have assessed three frameworks frequently referred to in extant research, and exposed how these three cover different dimensions of NSD practices. By exploring the practices of NSD empirically, this paper continues the ongoing discussion of what the relevant aggregated dimensions of NSD practices are. The detailed practices identified by interviewing 25 employees, all with key roles in relation to NSD in five large Scandinavian service firms, about their NSD practices, are clustered into three aggregated overarching dimensions of NSD practices: 1) identifying needs, 2) assur…

lcsh:Management. Industrial managementKnowledge managementInterviewProcess (engineering)media_common.quotation_subjectservice innovationExtant taxonManagement of Technology and Innovation0502 economics and businessSociologylcsh:Technological innovations. AutomationService innovationMarketingNew service developmentEngineering (miscellaneous)media_commonlcsh:HD45-45.2Practice theorybusiness.industry05 social scienceslcsh:HD28-70New Service DevelopmentService (economics)050211 marketingpractice theorybusiness050203 business & managementJournal of Innovation Management
researchProduct

Bone targeting compounds for radiotherapy and imaging: *Me(III)-DOTA conjugates of bisphosphonic acid, pamidronic acid and zoledronic acid

2016

Background Bisphosphonates have a high adsorption on calcified tissues and are commonly used in the treatment of bone disorder diseases. Conjugates of bisphosphonates with macrocyclic chelators open new possibilities in bone targeted radionuclide imaging and therapy. Subsequent to positron emission tomography (PET) examinations utilizing 68Ga-labelled analogues, endoradiotheraphy with 177Lu-labelled macrocyclic bisphosphonates may have a great potential in the treatment of painful skeletal metastases. Methods Based on the established pharmaceuticals pamidronate and zoledronate two new DOTA-α-OH-bisphosphonates, DOTAPAM and DOTAZOL(MM1.MZ) were successfully synthesized. The ligands were labe…

lcsh:Medical physics. Medical radiology. Nuclear medicineBiodistributionMaterials sciencelcsh:R895-920Hydroxy bisphosphonatesSingle-photon emission computed tomography01 natural sciences030218 nuclear medicine & medical imagingAnalytical Chemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePharmacokineticsmedicineDOTAPharmacology (medical)Radiology Nuclear Medicine and imagingZoledronic acidPharmacologymedicine.diagnostic_test010405 organic chemistrybusiness.industryResearchBone metastaseslcsh:RM1-950Pamidronic acid177LuTheranostics68Ga0104 chemical sciencesZoledronic acidPETlcsh:Therapeutics. PharmacologyDOTAchemistryPositron emission tomographyNuclear medicinebusinessEx vivomedicine.drugEJNMMI Radiopharmacy and Chemistry
researchProduct

Transgenic Killer Commensal Bacteria as Mucosal Protectants

2001

As first line of defense against the majority of infections and primary site for their transmission, mucosal surfaces of the oral cavity and genitourinary, gastrointestinal, and respiratory tracts represent the most suitable sites to deliver protective agents for the prevention of infectious diseases. Mucosal protection is important not only for life threatening diseases but also for opportunistic infections which currently represent a serious burden in terms of morbidity, mortality, and cost of cures. Candida albicans is among the most prevalent causes of mucosal infections not only in immuno- compromised patients, such as HIV-infected subjects who are frequently affected by oral and esoph…

lcsh:Medicinemedicine.disease_causeEsophageal candidiasislcsh:TechnologyGeneral Biochemistry Genetics and Molecular BiologyMicrobiologymucosal immunotherapyCandida albicansmedicineAnimalsHumansTransgenesCandida albicanslcsh:ScienceKiller recombinant antibodiesAntibodies FungalGeneral Environmental ScienceMucous MembranebiologyGenitourinary systemTransmission (medicine)Streptococcuslcsh:Ttransgenic commensal bacterislcsh:RCandidiasisMucous membraneStreptococcusGeneral Medicinebiology.organism_classificationmedicine.diseasemedicine.anatomical_structureProtective AgentsToxicityImmunologyVaginalcsh:QFemaleDirections in ScienceThe Scientific World Journal
researchProduct

Strategie autofinzionali in "Leggenda privata" di Michele Mari

2019

Leggenda privata (2017) is the latest in a series of autobiographical writings by Michele Mari. The novel is the factual narration of the author's childhood and adolescence, documented by family photos, but is also the narration of a fictional and fantastic situation of writing, where the reader is involved in live recording. In particular, the narrative framework is structured almost like a personal essay that engages dialogically the norms and potentials, opportunities and risks of a theory of autobiography. The purpose of this article is to explore the limits, the difficulties, indeed the impossibility of autobiographical writing in Leggenda Privata, which instead verges towards a comple…

lcsh:P101-410OnomasticSettore L-FIL-LET/14 - Critica Letteraria E Letterature Comparatelcsh:Translating and interpretinglcsh:Geography. Anthropology. Recreationlcsh:P306-310Michele Marilcsh:Language. Linguistic theory. Comparative grammarAutofictionlcsh:Gcornice narrativaMichele Mari; autofiction; autobiografia; onomastica; cornice narrativaNarrative ThresholdAutobiografiaAutobiographyonomastica
researchProduct

The afterworld space in the "Poem strip" (1969) by Dino Buzzati

2018

L’obiettivo del contributo è l’analisi dello spazio oltremondano in Poema a fumetti(1969) di Dino Buzzati, graphic novelante-litteram. Buzzati riscrive, in chiave ultramoderna e laica, sia il mito di Orfeo ed Euridice, restituendo la centralità alla potenza della musica, sia il mito della discesa agli inferi, toposassoluto della letteratura italiana a partire da Dante e rappresentazione allegorica dell’oltretomba cristiano. In particolare Buzzati inventa una rappresentazione visiva dello spazio dell’aldilà dove sono essenziali due elementi: la continuità/discontinuità dei due mondi, nominalmente diversi, e le cornici che permettono il passaggio da un mondo all’altro. Il motivo ricorrente di…

lcsh:P101-410lcsh:Translating and interpretinglcsh:Geography. Anthropology. RecreationDescent into hellPoema a fumettiDino Buzzati; Poem strip; Discesa agli Inferi; Orfeolcsh:P306-310Discesa agli Inferilcsh:Language. Linguistic theory. Comparative grammarDino Buzzativiaggio agli inferilcsh:GDino Buzzati; Poema a fumetti; viaggio agli inferi; OrfeoDino Buzzati; Poema a fumetti; Descent into hell; OrpheusPoem stripOrfeoDino Buzzati; Poem strip; Descent into hell; OrpheusOrpheusBetween
researchProduct

Editorial to the ‘Special Issue—Solar Photovoltaic System Engineering’ of AIMS Energy

2020

lcsh:Production of electric energy or power. Powerplants. Central stationsEngineeringFuel TechnologyRenewable Energy Sustainability and the Environmentbusiness.industryPhotovoltaic systemlcsh:TK1001-1841Energy Engineering and Power TechnologybusinessEngineering physicsEnergy (signal processing)AIMS Energy
researchProduct

Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

2010

Abstract Background Cancer genomes display characteristic patterns of chromosomal imbalances, often with diagnostic and prognostic relevance. Therefore assays for genome-wide copy number screening and simultaneous detection of copy number alterations in specific chromosomal regions are of increasing importance in the diagnostic work-up of tumors. Results We tested the performance of Multiplex Amplicon Quantification, a newly developed low-cost, closed-tube and high-throughput PCR-based technique for detection of copy number alterations in regions with prognostic relevance for neuroblastoma. Comparison with array CGH and the established Multiplex Ligation-dependent Probe Amplification method…

lcsh:QH426-470DNA Copy Number Variationslcsh:BiotechnologyCopy number analysisARRAY CGHBiologyProteomicsGenomePolymerase Chain Reactionlaw.inventionNeuroblastomalawlcsh:TP248.13-248.65GeneticsMedicine and Health SciencesHumansSUBGROUPSMultiplexBiologyPolymerase chain reactionDEMENTIANucleic acid amplification techniqueAmpliconMolecular biologylcsh:GeneticsHuman medicineDNA microarrayNucleic Acid Amplification TechniquesBiotechnologyResearch Article
researchProduct