Search results for "lcsh:T"

showing 10 items of 2832 documents

A Snapshot on the On-Label and Off-Label Use of the Interleukin-1 Inhibitors in Italy among Rheumatologists and Pediatric Rheumatologists: A Nationwi…

2016

Background: Interleukin (IL)-1 inhibitors have been suggested as possible therapeutic options in a large number of old and new clinical entities characterized by an IL-1 driven pathogenesis. Objectives: To perform a nationwide snapshot of the on-label and off-label use of anakinra (ANA) and canakinumab (CAN) for different conditions both in children and adults. Methods: We retrospectively collected demographic, clinical, and therapeutic data from both adult and pediatric patients treated with IL-1 inhibitors from January 2008 to July 2016. Results: Five hundred and twenty-six treatment courses given to 475 patients (195 males, 280 females; 111 children and 364 adults) were evaluated. ANA wa…

medicine.medical_specialtyautoinflammatory disorders treatment interleukin (IL)-1 anakinra canakinumabDoseanakinra; autoinflammatory disorders; canakinumab; interleukin (IL)-1; treatmentautoinflammatory disorders; treatment; interleukin (IL)-1; anakinra; canakinumab030204 cardiovascular system & hematologyOff-label usecanakinumab03 medical and health sciencesSettore MED/38 - Pediatria Generale E Specialistica0302 clinical medicineInternal medicinemedicinePharmacology (medical)Interleukin-1 inhibitorsAdverse effectOriginal Research030203 arthritis & rheumatologyPharmacologyAnakinratreatmentbusiness.industrylcsh:RM1-950Anakinra; Autoinflammatory disorders; Canakinumab; Interleukin (IL)-1; Treatment; Pharmacology; Pharmacology (medical)InterleukinRetrospective cohort studySurgeryinterleukin (IL)-1Canakinumablcsh:Therapeutics. PharmacologyAutoinflammatory disorderSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAautoinflammatory disordersAntirheumatic drugsbusinessmedicine.druganakinra
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The study on the importance of effects after the ultrasound use in the recovery of patients with lower lumbar discopathy

2018

The low back pain is a public health problem, affecting the adult population and the young one. It is estimated that 90% of the population will experience at least one episode of lower lumbar pain during their lifetime, half of whom may have a second painful episode during the same year. Frequently, the mechanical cause (the pain is somatic and deep, caused by lesions in the musculoskeletal tendon or ligament, in non-specific degenerative or inflammatory diseases) but also the psychosocial factors are incriminated. In low back pain, ultrasounds were used for the analgesic effect, muscle relaxing and for the hyperemia effect. The paper has as purpose the study of the effects of applying ultr…

medicine.medical_specialtybusiness.industryultrasoundUltrasoundlcsh:RM1-950General MedicinekinetoteraphyLumbarlcsh:Therapeutics. Pharmacologymedicinephysical therapyRadiologybusinesslow back painBalneo Research Journal
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Enteral Nutrition in Pancreaticoduodenectomy: A Literature Review

2015

Pancreaticoduodenectomy (PD) is considered the gold standard treatment for periampullory carcinomas. This procedure presents 30%–40% of morbidity. Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes af…

medicine.medical_specialtydelayed gastric emptyingGastroparesismedicine.medical_treatmentlcsh:TX341-641ReviewPancreaticoduodenectomylaw.inventionPancreatic FistulaEnteral NutritionPostoperative ComplicationsMeta-Analysis as TopicRandomized controlled trialRisk FactorslawmedicineHumansGastroparesisRandomized Controlled Trials as TopicNutrition and DieteticsGastric emptyingEnteral nutrition; pancreaticoduodenectomy; delayed gastric emptying; postoperative pancreatic fistula; postpancreatectomy hemorrhagebusiness.industryGeneral surgeryGold standardPerioperativeLength of Staymedicine.diseasePancreaticoduodenectomySurgerySettore MED/18 - Chirurgia GeneraleTreatment OutcomeParenteral nutritionPancreatic fistulapostoperative pancreatic fistulabusinesslcsh:Nutrition. Foods and food supplypostpancreatectomy hemorrhageFood ScienceNutrients
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Oxidative Stress in Diabetic Retinopathy

2021

Diabetic Retinopathy (DR) is a progressive asymptomatic neuro-vascular complication of diabetes that triggers irreversible retinal damage [...]

medicine.medical_specialtygenetic structuresPhysiologybusiness.industryRetinal damagelcsh:RM1-950Clinical BiochemistryCell BiologyDiabetic retinopathymedicine.diseasemedicine.disease_causeBiochemistryAsymptomaticEditorialn/alcsh:Therapeutics. PharmacologyOphthalmologyDiabetes mellitusmedicinemedicine.symptombusinessComplicationMolecular BiologyOxidative stressAntioxidants
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Good oral health and diet.

2011

An unhealthy diet has been implicated as risk factors for several chronic diseases that are known to be associated with oral diseases. Studies investigating the relationship between oral diseases and diet are limited. Therefore, this study was conducted to describe the relationship between healthy eating habits and oral health status. The dentistry has an important role in the diagnosis of oral diseases correlated with diet. Consistent nutrition guidelines are essential to improve health. A poor diet was significantly associated with increased odds of oral disease. Dietary advice for the prevention of oral diseases has to be a part of routine patient education practices. Inconsistencies in …

medicine.medical_specialtylcsh:BiotechnologyHealth Toxicology and MutagenesisMEDLINElcsh:MedicineDentistryNutritional StatusHealthy eatingOral HealthReview ArticleOral healthSettore MED/28 - Malattie Odontostomatologichelcsh:TP248.13-248.65GeneticsMedicineHumansMolecular Biologybusiness.industrylcsh:RNutrition GuidelinesGeneral MedicineDietary adviceDietstomatognathic diseasesNutrition trainingTooth DiseasesFamily medicineMolecular MedicineOral diseasebusinessMouth Diseasesoral health dietBiotechnologyPatient educationJournal of biomedicinebiotechnology
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Pre-pregnancy and early pregnancy dietary behavior in relation to maternal and newborn health in the Norwegian Fit for Delivery study – a post hoc ob…

2018

Background Randomized controlled trials targeting maternal dietary and physical activity behaviors during pregnancy have generally failed to accomplish reductions in the prevalence of adverse maternal and neonatal outcomes. Interventions carried out during pregnancy could thus be missing the mark in maximizing intervention health benefit. Objective To investigate whether pre-pregnancy and early pregnancy dietary behavior as reported at inclusion into the Norwegian Fit for Delivery (NFFD) trial was associated with maternal and neonatal outcomes irrespective of subsequent randomization assignment. Design The study is a post-hoc observational analysis of data from a randomized controlled lifes…

medicine.medical_specialtylcsh:TX341-641Logistic regressionpreconception dietneonatal outcomePreeclampsialaw.inventionpreeclampsia03 medical and health sciences0302 clinical medicineRandomized controlled triallawmedicine030212 general & internal medicinePregnancy030219 obstetrics & reproductive medicineNutrition and Dieteticspreconceptionpregnancy complicationsbusiness.industryObstetricsPublic Health Environmental and Occupational Healthpreterm birthdiet scoreOdds ratiomedicine.diseaseConfidence intervalgestational weight gainGestationOriginal Articlepregnancy healthmedicine.symptomdietbusinesslcsh:Nutrition. Foods and food supplyWeight gainFood ScienceFood & Nutrition Research
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Prescription of Antibiotic Prophylaxis for Dental Implant Surgery in Healthy Patients: A Systematic Review of Survey-Based Studies

2021

Background: Systemic antibiotic prophylaxis is frequently prescribed by dentists performing dental implant surgery to avoid premature implant failure and postoperative infections. The scientific literature suggests that a single preoperative dose suffices to reduce the risk of early dental implant failure in healthy patients.Material and Methods: A systematic review was made based on an electronic literature search in the PubMed-Medline, Embase, Web of Science, Scopus and Open Gray databases. The review addressed the question: “which antibiotic prophylaxis regimens are being used in dental implant surgery in healthy patients according to survey-based studies?” The identification, screening,…

medicine.medical_specialtymedicine.medical_treatment03 medical and health sciences0302 clinical medicineantibioticMedicinesurveyPharmacology (medical)030212 general & internal medicineAntibiotic prophylaxisMedical prescriptionDental implantPharmacologyResponse rate (survey)dental implantbusiness.industryGeneral surgerylcsh:RM1-950Implant failure030206 dentistryPerioperativeRegimenlcsh:Therapeutics. PharmacologyObservational studySystematic ReviewprophylaxisbusinessFrontiers in Pharmacology
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The role of electrotherapy in reducing the pain of patients with knee osteoarthritis during the COVID-19 pandemic

2020

Introduction. Osteoarthritis is considered to be the most common form of arthritis and a leading disability cause worldwide, especially due to the painful symptom. The latter is a clinical marker in evaluating the limits of joint mobility and therefore, the pain reduction is a goal of the recovery treatment for patients with knee osteoarthritis. The purpose of this study was to show whether the pain phenomenon characteristic of knee osteoarthritis can be reduced by electrotherapy, even in the context of the COVID-19 pandemic. Material and method. The study lasted 5 months and included 171 patients diagnosed clinically and radiologically with knee osteoarthritis. The followed parameters were…

medicine.medical_specialtymedicine.medical_treatmentAnalgesicArthritisContext (language use)Osteoarthritis010402 general chemistry01 natural sciencesknee osteoarthritisanalgesic electrotherapy03 medical and health sciences0302 clinical medicineQuality of lifemedicineOutpatient clinicpain030203 arthritis & rheumatologybusiness.industrylcsh:RM1-950General Medicinemedicine.disease0104 chemical scienceslcsh:Therapeutics. PharmacologyElectrotherapyPhysical therapyAnxietymedicine.symptomrecovery treatmentbusinessBalneo Research Journal
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Beneficial Effects of Leucine Supplementation on Criteria for Sarcopenia: A Systematic Review

2019

Objective: Treating sarcopenia remains a challenge, and nutritional interventions present promising approaches. We summarize the effects of leucine supplementation in treating older individuals with sarcopenia associated with aging or to specific disorders, and we focus on the effect of leucine supplementation on various sarcopenia criteria, e.g., muscular strength, lean mass, and physical performance. Methods: A literature search for articles related to this topic was performed on the relevant databases, e.g., the PubMed/Medline, Embase, EBSCO, Cochrane, Lilacs, and Dialnet. The identified articles were reviewed according to Preferred Reporting Items for Systematic reviews and meta-analyse…

medicine.medical_specialtymedicine.medical_treatmentMEDLINElcsh:TX341-641030209 endocrinology & metabolismReviewPhysical strengthelderlysarcopenia03 medical and health sciences0302 clinical medicineLeucineInternal medicineVitamin D and neurologyHumansMedicine030212 general & internal medicineNutrition and DieteticsRehabilitationbusiness.industrymedicine.diseaseSystematic reviewSarcopeniaDietary Supplementsmuscular massLean body massLeucinebusinesslcsh:Nutrition. Foods and food supplymuscular strengthFood ScienceNutrients
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The effect of the thrombolytic therapy on the early rehabilitation of patients with acute ischemic stroke – study report

2020

Introduction. r-TPA intravenous thrombolytic therapy is a big step in acute management of ischemic stroke (IS) but is burdened by a small therapeutic window (max. 4.5 hours) that restricts patient access. NIH stroke scale (NIHSS) is the largest worldwide tool used by doctors in order to objectively quantify the severity of neurological impairment in acute IS, in the initial stage as well as in the subsequent stages. Material and method. The aim of this paper is to present the results of an observational, prospective, analytical study on a number of 110 patients with acute IS, hospitalized within two months in the Neurology Clinic of Sibiu (19 patients with thrombolytic therapy applied, 91 p…

medicine.medical_specialtynih stroke scalebusiness.industryneurological patternlcsh:RM1-950General Medicine030204 cardiovascular system & hematologyearly rehabilitation03 medical and health scienceslcsh:Therapeutics. Pharmacology0302 clinical medicineStudy reportEmergency medicineischemic strokemedicinebusinessEarly rehabilitationAcute ischemic stroke030217 neurology & neurosurgeryBalneo Research Journal
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