Search results for "leave"

showing 10 items of 372 documents

Superposing significant interaction rules (SSIR) method: a simple procedure for rapid ranking of congeneric compounds

2020

The Superposing Significant Interaction Rules (SSIR) method is revised and implemented. The method is a simple combinatorial procedure, which deals with in situ generated rules among a dichotomized congeneric molecular family, selecting the most probabilistically relevant ones. The mere counting of the number of relevant rules attached to new compounds generates a molecular ranking useful for database filtering, refinement and prediction. The algorithm only needs for a symbolic molecular representation and this allows for mining the database in a confidential manner. Third parties will not know the real compounds that are on the way to be worked out. The procedure is tested for a complete s…

Simple (abstract algebra)Computer sciencebusiness.industryQuímica combinatòriaPattern recognitionCombinatorial chemistrySSIR method; Congener series; Ranking; SAR; Balanced Leave-two-out cross validation (BL2O)General ChemistryArtificial intelligenceQuímicabusinessRanking (information retrieval)
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Long-term effects of soil management on ecosystem services and soil loss estimation in olive grove top soils

2016

Soil management has important effects on soil properties, runoff, soil losses and soil quality. Traditional olive grove (OG) management is based on reduced tree density, canopy size shaped by pruning and weed control by ploughing. In addition, over the last several decades, herbicide use has been introduced into conventional OG management. These management strategies cause the soil surface to be almost bare and subsequently high erosion rates take place. To avoid these high erosion rates several soil management strategies can be applied. In this study, three strategies were assessed in OG with conventional tillage in three plots of 1. ha each. Soil properties were measured and soil erosion …

Soil managementEnvironmental EngineeringSoil biodiversity010501 environmental sciencesOlive mill pomace01 natural sciencesSoil managementNo-till farmingEnvironmental ChemistryOlive leavesWaste Management and Disposal0105 earth and related environmental sciencesConventional tillageAndalucía04 agricultural and veterinary sciencesBodemfysica en LandbeheerPE&RCPollutionSoil qualitySoil conditionerSoil Physics and Land ManagementAgronomyAmendments040103 agronomy & agricultureSoil erosion0401 agriculture forestry and fisheriesEnvironmental scienceSoil fertilitySoil conservationOlive mill pomace
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Pesticide analysis in coffee leaves using a quick, easy, cheap, effective, rugged and safe approach and liquid chromatography tandem mass spectrometr…

2017

An analytical method using a quick, easy, cheap, effective, rugged and safe (QuEChERS) procedure for multi-residue determination of 52 pesticides in coffee leaf extractshas been developed and validated according to SANTE/11945/2015 guidelines. Different sorbent combinations for dispersive solid phase extraction (d-SPE) clean-up as well as dispersive liquid-liquid microextraction (DLLME) were tested. The relative standard deviations (RSDs) for the recovery of 87-94% of pesticides added to coffee leaf extracts,was ≤20% for samples spiked at concentrations up to 50ng*g-1 depending on the clean-up procedures. However, samples spiked with a 100ng*g-1 pesticide mixture gave RSDs>20% for most pest…

SorbentCoffeaFood Contamination010402 general chemistryQuechers01 natural sciencesBiochemistryCoffeeAnalytical ChemistryLiquid chromatography–mass spectrometryTandem Mass SpectrometrySolid phase extractionChromatographyChemistry010401 analytical chemistryOrganic ChemistryExtraction (chemistry)Solid Phase ExtractionPesticide ResiduesGeneral MedicineOrganic coffeePesticide0104 chemical sciencesClean-upPlant LeavesAdsorptionChromatography LiquidJournal of chromatography. A
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Light-induced proton slip and proton leak at the thylakoid membrane

2005

A treatment of leaves of Spinacia oleracea L. with light or with the thiol reagent dithiothreitol in the dark led to partly uncoupled thylakoids. After induction in intact leaves, the partial uncoupling was irreversible at the level of isolated thylakoids. We distinguish between uncoupling by proton slip, which means a decrease of the H+/e(-) -ratio due to less efficient proton pumping, and proton leak as defined by enhanced kinetics of proton efflux. Proton slip and proton leak made about equal contributions to the total uncoupling. The enhanced proton efflux kinetics corresponded to reduction of subunit CF1-gamma of the ATP synthase as shown by fluorescence labeling of thylakoid proteins …

SpinaciaLightProtonPhysiologyKineticsAnalytical chemistryPlant ScienceThylakoidsDithiothreitolElectron Transportchemistry.chemical_compoundSpinacia oleraceaChloroplast Proton-Translocating ATPasesPhotosynthesisATP synthasebiologybiology.organism_classificationPlant LeavesDithiothreitolchemistryPhotophosphorylationThylakoidbiology.proteinBiophysicsProtonsThioredoxinAgronomy and Crop ScienceATP synthase alpha/beta subunitsJournal of Plant Physiology
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Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2

2005

In the present study, we report that three new lupane triterpenes (1-3), in addition to 16 known ones (4-19), were isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis. Their structures were elucidated by spectral analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HSQC, and HMBC). The natural compounds and derivatives 6a, 6b, 9a, and 9b have been tested for potential anti-inflammatory activity, and several compounds including 3-epicalenduladiol (2), 11alpha-hydroxy-glochidone (3), rigidenol (6), acetoxy-rigidenol (6a), 11alpha-acetoxy-30-chloro-3-oxo-lup-20(29)-ene (6b), betulin (9), 28-acetoxy-betulin (9a), epibetul…

StereochemistryClinical BiochemistryPharmaceutical SciencePharmacognosyNitric OxideBiochemistryDinoprostoneTerpeneCelastraceaeMiceStructure-Activity Relationshipchemistry.chemical_compoundTriterpeneDrug DiscoveryAnimalsMolecular Biologychemistry.chemical_classificationBetulinbiologyMaytenusMacrophagesSpectrum AnalysisOrganic ChemistryBiological activityBacterial InfectionsMaytenusbiology.organism_classificationAntineoplastic Agents PhytogenicTriterpenesTerpenoidEndotoxinsPlant LeaveschemistryMolecular MedicineBioorganic & Medicinal Chemistry
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Crystal structure of [Cu(N-quinolin-8-yl-p-toluenesulfonamidate)2]: study of its interaction with DNA and hydrogen peroxide

2001

A new copper complex with N-quinolin-8-yl-p-toulenesulfonamide has been prepared and characterised. The compound crystallises in the triclinic system, space group P1, with a=13.457(3), b=15.067(5), c=18.589(3) A; α=112.05(2), β=93.92(2), γ=108.30(2)° and Z=4. The geometry of the Cu(II) ion is distorted square planar. The N-quinolin-8-yl-p-toulenesulfonamidate anion behaves as a bidentate ligand through the N s u l f o n a m i d a t e and N q u i n o l i n e atoms. The complex does not cleave DNA in the presence of hydrogen peroxide.

StereochemistryCrystal structureTriclinic crystal systemCrystallography X-RayBiochemistryIonInorganic Chemistrychemistry.chemical_compoundCleaveOrganometallic CompoundsHydrogen peroxidechemistry.chemical_classificationSulfonamidesCopper complexDose-Response Relationship DrugMolecular StructureHydrolysisSpectrum AnalysisDNAHydrogen PeroxideSulfonamideCrystallographychemistryQuinolinesCopperDNADNA DamagePlasmidsJournal of Inorganic Biochemistry
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Cytotoxic bufadienolides from the leaves of a medicinal plant Melianthus comosus collected in South Africa.

2020

Abstract From the leaves of South African medicinal plant Melianthus comosus, four previously undescribed bufadienolides, 16β-formyloxymelianthugenin (1), 2β-acetoxymelianthusigenin (2), 2β-hydroxy-3β,5β-di-O-acetylhellebrigenin (3), and 2β-acetoxy-5β-O-acetylhellebrigenin (4) were isolated together with two known bufadienolides. The structural elucidation of the compounds was based on 1D and 2D NMR spectroscopy, high-resolution mass spectrometry, and other spectroscopic methods. The relative configurations were determined by single-crystal X-ray crystallography analysis and NOESY correlations. The isolated compounds displayed strong cytotoxicity against MCF-7 breast cancer cells, sensitive…

StereochemistryMolecular ConformationMass spectrometry01 natural sciencesBiochemistrySouth AfricaStructure-Activity RelationshipCell Line TumorDrug DiscoveryIc50 valuesCytotoxic T cellHumansCytotoxicityMolecular BiologyCell ProliferationPlants MedicinalbiologyDose-Response Relationship Drug010405 organic chemistryChemistryOrganic ChemistryStereoisomerismMelianthus comosusbiology.organism_classificationAntineoplastic Agents Phytogenic0104 chemical sciencesBufanolidesPlant Leaves010404 medicinal & biomolecular chemistryBreast cancer cellsDrug Screening Assays AntitumorTwo-dimensional nuclear magnetic resonance spectroscopyBioorganic chemistry
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Anti-inflammatory and antiallergic activity in vivo of lipophilic Isatis tinctoria extracts and tryptanthrin.

2006

The effects of a supercritical CO2 (SFE) extract, a dichloromethane (DCM) extract from Isatis tinctoria leaf and the alkaloidal constituent tryptanthrin were studied in acute and subchronic experimental models of inflammation. The SFE and DCM extracts showed anti-inflammatory activity in the carrageenan-induced acute mouse paw oedema (ED50 values of 78 mg/kg and 165 mg/kg P. O., respectively) and in the acute tetradecanoylphorbol acetate (TPA)-induced mouse ear oedema in oral (62% and 32% oedema reduction at 100 and 125 mg/kg, respectively) and topical application (37% and 33% reduction of oedema at 0.5 mg/ear). In contrast, tryptanthrin showed no significant anti-inflammatory effect. The D…

Stereochemistrymedicine.drug_classAnti-Inflammatory AgentsPharmaceutical ScienceAdministration OralPharmacognosyPharmacologyAdministration CutaneousCarrageenanAnti-inflammatoryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundMiceIn vivolawDrug DiscoveryAnti-Allergic AgentsmedicineHypersensitivityAnimalsEdemaIsatisED50Pharmacologybiologybusiness.industryPlant ExtractsOrganic ChemistryIsatisbiology.organism_classificationCarrageenanPlant LeavesComplementary and alternative medicinechemistryTetradecanoylphorbol AcetateQuinazolinesMolecular MedicineTetradecanoylphorbol AcetateFemalePhytotherapybusinessDrugs Chinese HerbalPhytotherapyPlanta medica
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Current and New Insights in the Sustainable and Green Recovery of Nutritionally Valuable Compounds from Stevia rebaudiana Bertoni.

2015

International audience; The South American plant Stevia rebaudiana Bertoni is a great source of noncaloric sweeteners (steviol glycosides), mainly concentrated in its leaves, but also has important antioxidant compounds (vitamin C, polyphenols, chlorophylls, and carotenoids) and other important macro- and micronutrients such as folic acid and all of the essential amino acids except tryptophan. Traditionally, conventional methods have been used to recover nutritionally valuable compounds from plant food matrices. However, nowadays, the need for obtaining greener, sustainable, and viable processes has led both food industries and food scientists to develop new processes in full correspondence…

Stevia rebaudiana; food additives; nutraceuticals; conventional extraction; pulsed electric technologies; acoustic technologies; sub- and supercritical fluid extraction; microwave assisted extraction[SDV.BIO]Life Sciences [q-bio]/Biotechnologyfood.ingredient[SDV]Life Sciences [q-bio]microwave assisted extractionSteviolBiologyPlant foodschemistry.chemical_compoundpulsed electric technologiesfoodNutraceuticalStevia[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineeringacoustic technologiesnutraceuticals2. Zero hungerbusiness.industryPlant ExtractsFood additivefood and beveragesGreen Chemistry TechnologyGeneral Chemistrysub- and supercritical fluid extractionBiotechnologyfood additivesPlant LeavesStevia rebaudianachemistryFolic acidPolyphenolSouth americanGeneral Agricultural and Biological Sciencesbusinessconventional extraction[SDV.AEN]Life Sciences [q-bio]/Food and NutritionNutritive ValueStevia rebaudianaJournal of agricultural and food chemistry
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Short-term response to waterlogging in Quercus petraea and Quercus robur: A study of the root hydraulic responses and the transcriptional pattern of …

2015

International audience; We characterized the short-term response to waterlogging in Quercus petraea (Matt.) Liebl. and Quercus robur L. as the initial response towards their known long-term differences in tolerance to waterlogging. One-month old seedlings were subjected to hypoxic stress and leaf gas exchange, shoot water potential (Psi(s)) and root hydraulic conductivity (Lp(r)) were measured. In parallel, the expression of nine aquaporins (AQPs) along the primary root was analysed by quantitative RT-PCR. Results showed a similar reduction in net assimilation (A) and stomatal conductance (g(s)) for the two species. Notably, the response of Lpr differed temporally between the two species. Q…

Stomatal conductanceTime FactorsTranscription GeneticPhysiology[SDE.MCG]Environmental Sciences/Global ChangesAquaporinPlant ScienceAquaporinsPlant RootsQuercus roburQuercusHydraulic conductivityGene Expression Regulation PlantBotanyGeneticsHypoxiaQuercus robur (pedunculate oak)Plant ProteinsQuercus petraea (sessile oak)Water transportbiologyWaterWater channelbiology.organism_classificationOxygenPlant Leaves[ SDE.MCG ] Environmental Sciences/Global ChangesShootQuercus petraeaStress conditionsRoot hydraulic conductivityPlant ShootsPlant Physiology and Biochemistry
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