Search results for "lesa"
showing 10 items of 200 documents
Thymic Hyperplasia with Lymphoepithelial Sialadenitis (LESA)-Like Features: Strong Association with Lymphomas and Non-Myasthenic Autoimmune Diseases.
2021
Thymic hyperplasia (TH) with lymphoepithelial sialadenitis (LESA)-like features (LESA-like TH) has been described as a tumor-like, benign proliferation of thymic epithelial cells and lymphoid follicles. We aimed to determine the frequency of lymphoma and autoimmunity in LESA-like TH and performed retrospective analysis of cases with LESA-like TH and/or thymic MALT-lymphoma. Among 36 patients (21 males) with LESA-like TH (age 52 years, 32&ndash
Disparate miRNA expression in serum and plasma of patients with acute myocardial infarction: a systematic and paired comparative analysis
2020
AbstractDespite the promising value of miRNAs in the diagnostic and prognostic of cardiovascular disease (CVD), recent meta-analyses did not support their potential. Methodological variances in studies may interfere with miRNA profile and affect their results. This study determines if the blood starting material is a source of variance in miRNA profile by performing a paired comparison in plasma and serum of the expression of primary miRNAs associated with CVD. Circulating miRNA yield was similar in both plasma and serum, although a significant increase was observed in patients with Non-ST-elevation myocardial infarction (NSTEMI) compared to control volunteers. When normalized by the expres…
Lifespan Changes of the human brain in Alzheimer's disease
2018
[EN] Brain imaging studies have shown that slow and progressive cerebral atrophy characterized the development of Alzheimer's Disease (AD). Despite a large number of studies dedicated to AD, key questions about the lifespan evolution of AD biomarkers remain open. When does the AD model diverge from the normal aging model? What is the lifespan trajectory of imaging biomarkers for AD? How do the trajectories of biomarkers in AD differ from normal aging? To answer these questions, we proposed an innovative way by inferring brain structure model across the entire lifespan using a massive number of MRI (N = 4329). We compared the normal model based on 2944 control subjects with the pathological …
Influencia del aceite de coco en enfermos de alzhéimer a nivel cognitivo.
2017
Resumen Introducción: la enfermedad de Alzheimer es a día de hoy la demencia neurodegenerativa con mayor prevalencia en el primer mundo. Este hecho, unido a la falta de tratamiento farmacológico que cure la enfermedad, hace que se estudien nuevas estrategias terapéuticas no farmacológicas como es la administración de nutrientes. En este sentido, destaca la posible influencia del aceite de coco como fuente energética alternativa, capaz de frenar la muerte neuronal que se produce de modo progresivo en esta enfermedad. Objetivos: valorar el impacto del aceite de coco a nivel cognitivo en pacientes de alzhéimer, y concretamente en las áreas de orientación, lenguaje-construcción, fijación, cálcu…
How do presenters engage with their audience? Speakers multimodal interpersonal behaviour in research dissemination talks
2020
Abstract Speakers in research dissemination talks are challenged with the need to connect with an audience that does not necessarily share their knowledge and expertise. This communicative situation can be particularly challenging for speakers using English both as a foreign language and for academic purposes. This study combines multimodal and ethnographic methods to explore how speakers of dissemination talks engage with their public. It focuses on four presenters’ use and combination of language, paralanguage, kinesics, proxemics and gaze during intensive moments of engagement. The results show that these interpersonal rich points consist of dense multimodal ensembles that serve to short…
Looking towards the Future of Language Assessment: Usability of Tablet PCs in Language Testing
2016
[EN] This research addresses the change in how the Spanish University Entrance Examination can be delivered in the future. There is a wide acknowledgement that computer tests are very demanding for the delivering institutions which makes computer language testing difficult to implement. However, the use of tablet PCs can facilitate the delivery at even lower cost than the regular computer based language testing. 183 students in their last year of high school took a computer based language test which included reading, writing, listening and speaking. The research aspects were 1) whether they feel at ease with the tablet PC exam; 2) if they felt that visual aspects were accessible and 3) whet…
Sexualitat en persones grans: Claus per entendre la satisfacció sexual i el seu vincle amb la salut sexual
2019
La satisfacció sexual s?ha convertit en una qüestió important dintre dels estudis sobre sexualitats, dels que sistemàticament les persones grans queden excloses al reduir la seua sexualitat a aspectes relacionats amb la mala salut. En aquest estudi s?analitza la satisfacció sexual amb la parella d?aquest grup de població a través de la Encuesta Nacional de Salud Sexual, prenent com a base el model biopsicosocial de la sexualitat (DeLamater, 2002) i considerant el gènere i diferents grups d?edat. Els resultats indiquen el caràcter multifactorial de la satisfacció sexual, prioritzant elements de natura relacional, social i cultural per sobre de l?estat de salut.
La implicatura en los blogs educativos. Una aproximación pragmática
2015
[ES] La tecnología está multiplicando las formas en que podemos comunicarnos. Desde la aparición de Internet, la construcción del discurso, los géneros discursivos y el lenguaje mismo se han visto afectados por las características de este nuevo modo de comunicarse. Aparecen discursos mixtos que hacen necesarios nuevos enfoques. Así, el estudio de la red desde una perspectiva pragmática ha abarcado diferentes aproximaciones (el género, la caracterización del lenguaje de los textos, etc.); los blogs han sido considerados como una forma de conversación. El presente trabajo estudia los blogs educativos desde el punto de vista de las máximas conversacionales de Grice, y, en particular, las impli…
Las dificultades para la educación integradora desde la perspectiva de futuros maestros de inglés
2009
This article presents and analyses the findings of a qualitative study about the perceptions expressed by prospective primary teachers of English about integration and response to special educational needs in the mainstream. The analysis of the data, obtained in the course of the practice teaching period of their course, evidences their ideas on integrative education; besides, a frequent lack of experiences of genuine integrative practices in such a critical period of professional preparation is identified. El presente artículo presenta y analiza los hallazgos de un estudio de naturaleza cualitativa sobre las percepciones que expresan futuros maestros especialistas de inglés en el transcurs…
Comparison between Spanish young and elderly people evaluated using Rivermead Behavioural Memory Test
2010
The first objective of this work was to compare scores obtained in the daily memory function between young and elderly people, and to check whether there are differences between the groups for each of the profile scores obtained in the memory test. A second aim of this paper is to study the relationship between everyday memory and age, while controlling for gender and educational level. The total and profile scores obtained in the Rivermead Behavioural Memory Test were compared in a sample of 60 young and 120 elderly people from Valencia (Spain). Results showed significant differences between the two groups: those between 18 and 30 years obtained a higher average than those over 65. Once th…