Search results for "life science"
showing 10 items of 15035 documents
Weak warning signals can persist in the absence of gene flow
2019
Aposematic organisms couple conspicuous warning signals with a secondary defense to deter predators from attacking. Novel signals of aposematic prey are expected to be selected against due to positive frequency-dependent selection. How, then, can novel phenotypes persist after they arise, and why do so many aposematic species exhibit intrapopulation signal variability? Using a polytypic poison frog (Dendrobates tinctorius), we explored the forces of selection on variable aposematic signals using 2 phenotypically distinct (white, yellow) populations. Contrary to expectations, local phenotype was not always better protected compared to novel phenotypes in either population; in the white popul…
CYGD: the Comprehensive Yeast Genome Database.
2005
The comprehensive resource is available under http://mips.gsf.de/genre/proj/yeast/.; International audience; The Comprehensive Yeast Genome Database (CYGD) compiles a comprehensive data resource for information on the cellular functions of the yeast Saccharomyces cerevisiae and related species, chosen as the best understood model organism for eukaryotes. The database serves as a common resource generated by a European consortium, going beyond the provision of sequence information and functional annotations on individual genes and proteins. In addition, it provides information on the physical and functional interactions among proteins as well as other genetic elements. These cellular network…
Development of healthy eating in children: from research to public health perspective
2019
International audience
What I say is not necessary what I do: pulses consumption in French adults
2018
International audience; The consumption of pulses in the human diet is considered to have several advantages: from a nutritional point of view, pulses are rich in dietary fibers, complex carbohydrate, minerals/vitamins and an important source of vegetal proteins. They are considered essential to insure food security and support environmental sustainability. Despite these benefits, the consumption of pulses in France has declined over the past decades, dropping from 7.2 kg in 1920 to 1.7 kg/ person per year in 2016. The aim of this study is to understand the representation of pulses among French non-vegetarian consumers, using a direct method (questionnaire) and an indirect method (scenario …
In-mouth air cavity volume changes and aroma release during mint consumption in human
2011
Poster; International audience
Vins d’appellations et gastronomie régionale. La genèse bourguignonne d’un modèle novateur (années 1920-1930)
2016
Boire du vin au restaurant, le choisir ou le faire choisir en fonction du plat sélectionné, étudier la carte des boissons tout comme le menu, ou encore commenter les domaines et les millésimes, sont des actes totalement intégrés par les amateurs de gastronomie du XXIe siècle. Et même si les associations mets vins tendent à s’internationaliser, déguster un produit local avec un vin du cru reste un moment important pour nombre de personnes souhaitant visiter une région. Cette démarche, si commune aujourd’hui, résulte pourtant d’un processus historique finalement assez récent et dont l’évidence contemporaine n’a rien de manifeste historiquement. En France au début du XXe siècle seulement, et d…
Data from: Impact of host nutritional status on infection dynamics and parasite virulence in a bird-malaria system
2013
1. Host resources can drive the optimal parasite exploitation strategy by offering a good or a poor environment to pathogens. Hosts living in resource-rich habitats might offer a favourable environment to developing parasites because they provide a wealth of resources. However, hosts living in resource-rich habitats might afford a higher investment into costly immune defences providing an effective barrier against infection. Understanding how parasites can adapt to hosts living in habitats of different quality is a major challenge in the light of the current human-driven environmental changes. 2. We studied the role of nutritional resources as a source of phenotypic variation in host exploi…
Modelling the removal and reversible immobilization of murine noroviruses in a Phaeozem under various contamination and rinsing conditions
2018
International audience; Enteric viruses entering the soil with contaminated irrigation water can reach groundwater or be internalized in plants through their roots without being inactivated. Their fate in the soil depends on the virus, the soil and the soil solution. In order to write a mathematical model suitable for a Calcaric Phaeozem, we investigated the removal of murine norovirus and reversible immobilization in aggregate columns according to a saturation procedure, conditions between contamination and rinsing time, temperature and soil solution. Viruses were quantified before and after 0.45‐μm filtration with an RT‐qPCR (real‐time polymerase chain reaction). Experimental results supp…
CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…
2021
Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…
Internalization of novel non-viral vector TAT-streptavidin into human cells
2007
BMC Biotechnology, 7 (1)