Search results for "life-span"
showing 10 items of 295 documents
CENTENARIANS TRANSCRIPTOME IS UNIQUE AND REVEALS A ROLE OF BCL-XL IN SUCCESSFUL AGING
2017
Centenarians not only enjoy an extraordinary aging, but also show a compression of morbidity. We identified 1721 mRNAs differentially expressed by PMBCs from centenarians when compared with septuagenarians and young people. Sub-network analysis led us to identify Bcl-xL as an important gene up-regulated in centenarians. We found that centenarians display lower plasma cytochrome C levels, higher mitochondrial membrane potential and also less cellular damage accumulation. Immune function is significantly impaired in septuagenarians compared with young people whereas centenarians maintain it. To further ascertain the functional role of Bcl-xL in cellular aging, we found in transduced lymphocyt…
Psychological predictors of homophobic bullying among adolescents and young adults: The role of parental psychological control and sensation seeking
2021
AbstractWe aimed to investigate the relationship between homophobic bullying, parental psychological control and sensation seeking among adolescents and young adults and to examine the mediating role of sensation seeking. The participants included 394 adolescents and young adults aged 15 to 20 years attending the 3rd, 4th and 5th years of two public high schools in Italian cities. Participants completed the Homophobic Bullying Scale, the Dependency—oriented and Achievement—oriented Parental Psychological Control, and the Sensation—Seeking Scale. The results showed that parental psychological control predicted bullying toward gay and lesbian people. However, the two dimensions of sensation s…
Childhood Obesity: The Relationship Between Negative Emotionality, Emotion Regulation, and Parenting Styles
2019
Objectives We aimed to compare obese children and their non-obese counterpart on children’s negative emotionality, emotion regulation and maternal parenting styles and to examine the joint contribution of children’s temperament and maternal styles to children’s obesity. Methods A total of 200 mothers were involved in this study, 100 with children diagnosed with obesity (49 boys, 51 girls; the age ranged from 6 to 12 years), and 100 with children with a normal weight (49 boys, 51 girls; the age ranged from 6 to 12 years). Mothers completed self-report measures on children’s emotionality, emotion regulation, and parenting styles. Results The comparison between the two groups showed that obese…
Cross-Cultural Validity of the Emotion Matching Task
2019
Objectives We aimed to provide evidence of the cross-cultural validity of the Emotion Matching Task (EMT), as a measure of emotion knowledge in preschool children in different cultures, namely, the United States, Italy, and Spain. In particular, we analyzed: (1) the psychometric properties of the scale in each of the three subsamples; (2) the relations between sex, age, verbal ability, and EK, in the overall sample and in the three different cultures; (3) the pattern of acquisition of the various dimensions of emotion knowledge in the overall sample and in the three different countries. Methods Participants were 500 children from Spain (N = 180), the United States (N = 158), and Italy (N = …
Parenting and adolescent adjustment: The mediational role of family self-esteem
2021
The present study analyzes the relationship between parental socialization practices, acceptance/involvement, and strictness/ imposition, and different indicators of adolescent adjustment, taking into account the role of family self-esteem. A sample of 848 Spanish adolescents (54.70% females) ranging in age from 14 to 18 years old (M = 16.11, SD = 1.10) participated in the study. A series of structural equations models (SEMs) were tested to examine the mediational role of family self-esteem in the relationship between parenting practices and the outcome variables that capture adolescent adjustment: emotional instability, antisocial behavior, and academic achievement. The influence of parent…
Building a System of Indicators to Evaluate the Right of a Child to Play
2018
Action in Perception: Prominent Visuo-Motor Functional Symmetry in Musicians during Music Listening.
2015
Musical training leads to sensory and motor neuroplastic changes in the human brain. Motivated by findings on enlarged corpus callosum in musicians and asymmetric somatomotor representation in string players, we investigated the relationship between musical training, callosal anatomy, and interhemispheric functional symmetry during music listening. Functional symmetry was increased in musicians compared to nonmusicians, and in keyboardists compared to string players. This increased functional symmetry was prominent in visual and motor brain networks. Callosal size did not significantly differ between groups except for the posterior callosum in musicians compared to nonmusicians. We conclude…
EMBEDDING CONTEXT IN INVESTIGATIONS OF AFFECTIVE VARIABILITY: AGE DIFFERENCES IN AFFECT-HEALTH LINKS
2017
Context plays a potentially important role in explaining variability in affective experiences and yet, has often been overlooked in this line of research. The current study used data from a lifespan sample of 398 German participants ranging between 12–88 years of age (M = 40, SD = 20). Participants completed computer assisted personal interviews regarding health and well-being measures, as well as experience sampling assessments of daily affective experiences and events (e.g., uplifts). Three indices of positive affect (PA) were created: mean PA, PA reactivity to uplifts, and PA variability. In general, greater mean PA and lower PA reactivity and variability were associated with better heal…
IN THE EYE OF THE BEHOLDER: NEGATIVE AFFECT VALUATION IN LATER ADULTHOOD
2018
Affective values may shape how affect is linked to health and well-being. Much of the work to date, however, has focused mostly on younger, European American adult samples. Yet, emotional experiences are known to take on greater importance in later life. In the current study, 313 participants (65+ years old) from the Daily Experiences and Well-Being Study (DEWS) completed baseline interviews, questionnaires, and 4–5 days of ecological momentary assessments (EMA). The baseline EMA surveys assessed momentary affect whereas the questionnaires assessed negative affect valuation (NAV): the extent to which people recognize value in negative emotional experiences in terms of their pleasantness, ap…
FREE RADICAL THEORY OF FRAILTY: MOLECULAR MECHANISMS OF FRAILTY RESULTING FROM OXIDATIVE STRESS
2018
The free radical theory of ageing provided an intellectual framework for many laboratories working on ageing. However, experimental and clinical evidence showing that high doses of antioxidants did not have an effect on ageing or on age-associated diseases, cast doubts on the validity of this theory. Data from our own laboratory showed that oxidative stress does not correlate with age, especially in the geriatric population, but rather with the frailty state. This has led us to postulate the free radical theory of frailty in which frailty is associated with oxidative stress, but age itself is not. Superoxide dismutase deficient mice are more frail than controls. But more importantly, we obs…