Search results for "liha"
showing 10 items of 620 documents
"Nyt nää läskit lähtee" : lihavuusleikkaukseen hakeutuminen kuluttajan ostopolkuna
2016
Tutkimuksen tavoitteena on selvittää, kuinka kuluttaja toimii hakeutuessaan vaativaan leikkaukseen. Tutkimuksessa pyritään ymmärtämään kuluttajan motivaatioita, emooti-oita ja vaikeita valintoja lihavuusleikkauksen ostopolulla. Tutkimuksen teoreettisena taustana toimivat kuluttajan ostopäätösprosessiin, erityisesti konstruktiiviseen päätös-prosessiin sekä emootioihin liittyvät teoriat ja aiempi tutkimus. Ylipainoiseen kuluttajaan, lihavuusleikkaukseen sekä terveyspalvelujen valintaan liittyvät tiedot ja teoriat muodos-tavat ostopolun maiseman. Tutkimuksessa haastateltiin 17 suomalaista kuluttajaa, joille oli suoritettu lihavuusleik-kaus. Haasteltaviksi valittiin sekä julkisen terveydenhuoll…
Acute neuromuscular, cardiorespiratory and endocrine responses and chronic adaptations to combined strength and endurance training in recreationally …
2013
Physical training considerations for optimizing performance in essential military tasks
2022
Physically demanding essential military tasks include load carriage, manual material handling and casualty evacuation. This narrative review characterizes the main physical attributes related to performance of these occupational tasks and reviews physical training intervention studies in military settings to improve performance in these military tasks. Load carriage performance requires both aerobic and neuromuscular fitness with greater emphasis on maximal strength and absolute maximal oxygen uptake, especially when carrying heavier loads. In manual material handling, maximal strength and power are strongly associated with discrete lifting, while muscular strength, muscular endurance and a…
Sit-stand workstations : effects on occupational sitting time, potential health benefits, and acute postural physiology
2017
Given that a high amount of sedentary behavior is a global health issue, reducing sitting time is emerging as a novel intervention strategy and a workplace health priority. Sit-stand workstations have been introduced to the workplace, and can be used to rotate between sitting and standing postures at work. It is important to develop and evaluate sit-stand interventions that aim to induce behavioral changes and potential health benefits, in order to effectively implement them into practice. Therefore, this thesis examined whether and to what extent sit-stand workstations can reduce occupational sitting and improve health indexes in a real workplace. The thesis included four studies in field …
Hormonikorvaushoito ja luurankolihaksisto : estrogeenisten ja progestogeenisten komponenttien vaikutukset lihassoluviljelmässä
2010
Yksi merkittävimmistä ikääntymiseen liittyvistä tapahtumista on luurankolihasten heikentyminen. Sarkopenia eli lihaskato heikentää ennen kaikkea ikääntyvän ihmisen terveyttä ja sitä kautta elämänlaatua, mutta sen kustannukset myös sosiaali- ja terveydenhuollolle ovat suuret. Naisilla lihasten suorituskyky heikkenee merkittävästi vaihdevuosien aikana, jolloin myös estrogeenin ja progesteronin tasot laskevat. Etenkin 17β-estradiolin (E2) tuotanto munasarjoissa loppuu vaihdevuosien aikana. Estrogeenin tiedetään vaikuttavan primaaristen sukupuoliominaisuuksien lisäksi myös moniin muihin kudoksiin, kuten luuhun ja lihaksiin. Vaihdevuosien mukanaan tuomia oireita hoidetaan usein estradiolia ja pr…
Effects of combined hormone replacement therapy or its effective agents on the IGF-1 pathway in skeletal muscle.
2010
Objectives To investigate the effects of combined hormone replacement therapy (HRT) and its effective agents on the IGF-1 signaling pathway. Design and methods To examine the effects of HRT on skeletal muscle in vivo, we utilized pre- and post-intervention samples from a randomized double blinded trial with 50–57-year-old women. The intervention included the year-long use of either HRT preparation (2 mg 17β-estradiol, E2; 1 mg norethisterone acetate, NETA, n = 10) or placebo (CO, n = 9). Microarray technology and quantitative PCR (qPCR) were used to study the expression of insulin-like growth factor I (IGF-1) and its splice variants as well as IGF-1 receptor, Akt1, mTOR, FOXO1, FOXO3, atrog…
Estradiol deficiency and skeletal muscle apoptosis: Possible contribution of microRNAs.
2020
Background Menopause leads to estradiol (E2) deficiency that is associated with decreases in muscle mass and strength. Here we studied the effect of E2 deficiency on miR-signaling that targets apoptotic pathways. Methods C57BL6 mice were divided into control (normal estrous cycle, n = 8), OVX (E2 deficiency, n = 7) and OVX + E2 groups (E2-pellet, n = 4). Six weeks following the OVX surgery, mice were sacrificed and RNA isolated from gastrocnemius muscles. miR-profiles were studied with Next-generation sequencing (NGS) and candidate miRs verified using qPCR. The target proteins of the miRs were found using in silico analysis and measured at mRNA (qPCR) and protein levels (Western blot). Resu…
Aging of the musculoskeletal system: How the loss of estrogen impacts muscle strength.
2019
Skeletal muscle weakness occurs with aging and in females this is compounded by the loss of estrogen with ovarian failure. Estrogen deficiency mediates decrements in muscle strength from both inadequate preservation of skeletal muscle mass and decrements in the quality of the remaining skeletal muscle. Processes and components of skeletal muscle that are affected by estrogens are beginning to be identified. This review focuses on mechanisms that contribute to the loss of muscle force generation when estrogen is low in females, and conversely the maintenance of strength by estrogen. Evidence is accumulating that estrogen deficiency induces apoptosis in skeletal muscle contributing to loss of…
Design and protocol of Estrogenic Regulation of Muscle Apoptosis (ERMA) study with 47 to 55-year-old women's cohort : novel results show menopause-re…
2018
Objective: The multidisciplinary Estrogenic Regulation of Muscle Apoptosis (ERMA) study was designed to reveal how hormonal differences over the menopausal stages affect the physiological and psychological functioning of middle-aged women. This paper describes the protocol and nonrespondent analysis of ERMA and novel findings on menopausal differences in blood count variables and their association with female sex hormones. Methods: Women aged 47 to 55 years were assigned to pre, early peri, late peri, and postmenopausal groups based on follicle-stimulating hormone (FSH) and bleeding diary. Multivariate linear regression models were constructed to estimate the association of 17b-estradiol (E…