Search results for "lino"

showing 10 items of 1310 documents

CCDC 2177984: Experimental Crystal Structure Determination

2022

Related Article: Elisabet De Bolòs, Marta Martínez-Abadía, Félix Hernández-Culebras, Alison Haymaker, Kyle Swain, Karol Strutyński, Benjamin L. Weare, Javier Castells-Gil□, Natalia M. Padial□, Carlos Martí-Gastaldo□, Andrei N. Khlobystov, Akinori Saeki, Manuel Melle-Franco, Brent L. Nannenga, Aurelio Mateo-Alonso△|2022|J.Am.Chem.Soc.|144|15443|doi:10.1021/jacs.2c06446

Space GroupCrystallographypoly-(44'-{211-di-t-butyl-7-[4-({[4-({[4-(prop-1-en-2-yl)phenyl]methylidene}amino)phenyl]imino}methyl)phenyl]quinoxalino[2'3':910]phenanthro[45-abc]phenazine-615-diyl}dibenzaldehyde)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 1830425: Experimental Crystal Structure Determination

2020

Related Article: Raphael C. A. Vaz, Isabela O. Esteves, Willian X. C. Oliveira, João Honorato, Felipe T. Martins, Lippy F. Marques, Guilherme L. dos Santos, Ricardo O. Freire, Larissa T. Jesus, Emerson F. Pedroso, Wallace C. Nunes, Miguel Julve, Cynthia L. M. Pereira|2020|Dalton Trans.|49|16106|doi:10.1039/D0DT02497J

Space GroupCrystallographytetra-n-butylammonium tetrakis((4-chloroanilino)(oxo)acetato)-(dimethyl sulfoxide)-gadolinium(iii) trihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 1958347: Experimental Crystal Structure Determination

2020

Space GroupCrystallographytetra-n-butylammonium tetrakis((4-chloroanilino)(oxo)acetato)-(dimethyl sulfoxide)-terbium(iii) trihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 1958348: Experimental Crystal Structure Determination

2020

Space GroupCrystallographytetra-n-butylammonium tetrakis((4-fluoroanilino)(oxo)acetato)-(dimethyl sulfoxide)-dysprosium(iii) dihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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CCDC 2104299: Experimental Crystal Structure Determination

2021

Related Article: Peter Happ, Christian Plenk, Eva Rentschler|2015|Coord.Chem.Rev.|289-290|238|doi:10.1016/j.ccr.2014.11.012

Space GroupCrystallographytetrakis(mu3-salicylhydroximato-NOOO'O'')-(mu-2-benzoxazolinonato-NO)-(mu2-pivalato-OO')-pentakis(morpholine-N)-(methanol-O)-cobalt(ii)-tetra-cobalt(iii) methanol solvate monohydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

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Galleria di ritratti. Stampe di incisori francesi dei secoli XVII e XVIII

2009

Stampe ritrattobulino incisori Francia

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Electrostatic Contribution to the Surface Pressure of Charged Monolayers Containing Polyphosphoinositides

2008

Structural and functional studies of lateral heterogeneity in biological membranes have underlined the importance of membrane organization in biological function. Most inquiries have focused on steric determinants of membrane organization, such as headgroup size and acyl-chain saturation. This manuscript reports a combination of theory and experiment that shows significant electrostatic contributions to surface pressures in monolayers of phospholipids where the charge spacing is smaller than the Bjerrum length. For molecules with steric cross sections typical of phospholipids in the cell membrane (approximately 50 A(2)), only polyphosphoinositides achieve this threshold. The most abundant s…

Steric effectsModels MolecularMembrane FluiditySurface PropertiesLipid BilayersStatic ElectricityBiophysics010402 general chemistryBjerrum length01 natural sciences03 medical and health sciencesPhosphatidylinositol PhosphatesMonolayerMembrane fluidityPressureComputer SimulationLipid bilayer030304 developmental biology0303 health sciencesChromatographyMembranesHydrogen bondChemistryBiological membrane0104 chemical sciencesModels ChemicalChemical physicsIonic strength

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Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

2021

AbstractThe five-membered pyrrolidine ring is one of the nitrogen heterocycles used widely by medicinal chemists to obtain compounds for the treatment of human diseases. The great interest in this saturated scaffold is enhanced by (1) the possibility to efficiently explore the pharmacophore space due to sp3-hybridization, (2) the contribution to the stereochemistry of the molecule, (3) and the increased three-dimensional (3D) coverage due to the non-planarity of the ring—a phenomenon called “pseudorotation”. In this review, we report bioactive molecules with target selectivity characterized by the pyrrolidine ring and its derivatives, including pyrrolizines, pyrrolidine-2-one, pyrrolidine-2…

Steric effectsPyrrolidinesMolecular StructureChemistryDrug discoveryEnantioselective synthesisStereoisomerismGeneral ChemistryReviewAnti-inflammatory and analgesic agentsRing (chemistry)Combinatorial chemistrySettore CHIM/08 - Chimica FarmaceuticaPyrrolidineProlinolPyrrolidinechemistry.chemical_compoundAntidiabeticsDrug DiscoveryPseudorotationHumansAnticancer and antibacterial agentsPharmacophoreCentral nervous system diseases

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Different Dissolution Media Lead to Different Crystal Structures of Talinolol with Impact on Its Dissolution and Solubility

2003

During the performance of dissolution tests with immediate and controlled-release talinolol tablets it was detected that the type of the buffer used as dissolution medium had a strong influence on the solubility and the dissolution behavior of the drug. It was proven that talinolol appeared in different crystal structures with strongly differing solubilities when pure water, acetate, or phosphate buffers were employed as dissolution media. The resulting crystal structures were characterized by means of light microscopy, differential scanning calorimetry, and X-ray powder diffraction. All methods were adjuvant to detect changes in talinolol crystal structures. The different solubility and di…

Surface PropertiesSodiumAdrenergic beta-AntagonistsPharmaceutical Sciencechemistry.chemical_elementSodium ChlorideDosage formlaw.inventionPropanolamineschemistry.chemical_compoundX-Ray DiffractionPulmonary surfactantlawDrug DiscoverySolubilityCrystallizationDissolutionPharmacologyChromatographyCalorimetry Differential ScanningChemistryOsmolar ConcentrationOrganic ChemistryHydrogen-Ion ConcentrationSolubilityIonic strengthDelayed-Action PreparationsSolventsCrystallizationTalinololNuclear chemistryDrug Development and Industrial Pharmacy

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Pump currents generated by the purified Na+K+-ATPase from kidney on black lipid membranes.

1985

The transport activity of purified Na+K+-ATPase was investigated by measuring the electrical pump current induced on black lipid membranes. Discs containing purified Na+K+-ATPase from pig kidney were attached to planar lipid bilayers in a sandwich-like structure. After the addition of only microM concentrations of an inactive photolabile ATP derivative [P3-1-(2-nitro)phenylethyladenosine 5'-triphosphate, caged ATP] ATP was released after illumination with u.v.-light, which led to a transient current in the system. The transient photoresponse indicates that the discs and the underlying membrane are capacitatively coupled. Stationary pump currents were obtained after the addition of the H+, N…

SwineSodium-Potassium-Exchanging ATPaseLipid BilayersDiaphragm pumpBiologyKidneyGeneral Biochemistry Genetics and Molecular BiologyOuabainValinomycinchemistry.chemical_compoundmedicineAnimalsVanadateNa+/K+-ATPaseLipid bilayerMolecular BiologyIon transporterPhotolysisGeneral Immunology and MicrobiologyGeneral NeuroscienceCell MembraneKineticsBiochemistrychemistryBiophysicsThermodynamicsSodium-Potassium-Exchanging ATPasemedicine.drugResearch Article

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