Search results for "living system"
showing 9 items of 19 documents
Concept of Client-Server Environment for Agent-Based Modeling and Simulation of Living Systems
2015
In the paper a concept for integrated and simple-to-use agent-based modeling and simulation environment is presented. The modeling environment allows simulating massive agent-based systems. Modeling environment itself is not domain specific, but it is expandable and allows creating domain-specific models. Hierarchical environment structure is supported. Individual agents could evolve by its individual path and pace. We use the General Living Systems theory as a reference model to check whether proposed modeling and simulation environment may also be used to describe models of living systems that are most complex systems around. The main concepts of proposed modeling environment such as agen…
Molecular communication relays for dynamic cross-regulation of self-sorting fibrillar self-assemblies
2021
Description
On the modeling of nonlinear interactions in large complex systems
2010
Abstract This work deals with the modeling of large systems of interacting entities in the framework of the mathematical kinetic theory for active particles. The contents are specifically focused on the modeling of nonlinear interactions which is one of the most important issues in the mathematical approach to modeling and simulating complex systems, and which includes a learning–hiding dynamics. Applications are focused on the modeling of complex biological systems and on immune competition.
Beyond free will : The embodied emergence of conscious agency
2019
Is it possible to reconcile the concept of conscious agency with the view that humans are biological creatures subject to material causality? The problem of conscious agency is complicated by the tendency to attribute autonomous powers of control to conscious processes. In this paper, we offer an embodied process model of conscious agency. We begin with the concept of embodied emergence – the idea that psychological processes are higher-order biological processes, albeit ones that exhibit emergent properties. Although consciousness, experience, and representation are emergent properties of higher-order biological organisms, the capacity for hierarchical regulation is a property of all livin…
Self-organization of active particles by quorum sensing rules
2018
Many microorganisms regulate their behaviour according to the density of neighbours. Such quorum sensing is important for the communication and organisation within bacterial populations. In contrast to living systems, where quorum sensing is determined by biochemical processes, the behaviour of synthetic active particles can be controlled by external fields. Accordingly they allow to investigate how variations of a density-dependent particle response affect their self-organisation. Here we experimentally and numerically demonstrate this concept using a suspension of light-activated active particles whose motility is individually controlled by an external feedback-loop, realised by a particl…
Mechanics and self-organization in tissue development
2021
Self-organization is an all-important feature of living systems that provides the means to achieve specialization and functionality at distinct spatio-temporal scales. Herein, we review this concept by addressing the packing organization of cells, the sorting/compartmentalization phenomenon of cell populations, and the propagation of organizing cues at the tissue level through traveling waves. We elaborate on how different theoretical models and tools from Topology, Physics, and Dynamical Systems have improved the understanding of self-organization by shedding light on the role played by mechanics as a driver of morphogenesis. Altogether, by providing a historical perspective, we show how i…
Designing de novo: interdisciplinary debates in synthetic biology
2013
Synthetic biology is often presented as a promissory field that ambitions to produce novelty by design. The ultimate promise is the production of living systems that will perform new and desired functions in predictable ways. Nevertheless, realizing promises of novelty has not proven to be a straightforward endeavour. This paper provides an overview of, and explores the existing debates on, the possibility of designing living systems de novo as they appear in interdisciplinary talks between engineering and biological views within the field of synthetic biology. To broaden such interdisciplinary debates, we include the views from the social sciences and the humanities and we point to some fu…
A Neuro-Ethological Approach for the TSP: Changing Metaphors in Connectionist Models.
1994
Biological systems often offer solutions to difficult problems which are not only original but also efficient. Connectionist models have been inspired by neural systems and successfully applied to the formulation of algorithms for solving complex problems such as the travelling salesman problem. In this paper we extend the connectionist metaphor to include an ethological account of how problems similar to the travelling salesman problem are solved by real living systems. A model is presented in which a population of neural networks with simple sensory-motor systems evolve genetically in simulated environments which represent the problem instances to be solved. Preliminary results are discu…
Feedback and Communication in Active Hydrogel Spheres with pH Fronts: Facile Approaches to Grow Soft Hydrogel Structures
2021
Abstract Compartmentalized reaction networks regulating signal processing, communication and pattern formation are central to living systems. Towards achieving life‐like materials, we compartmentalized urea‐urease and more complex urea‐urease/ester‐esterase pH‐feedback reaction networks into hydrogel spheres and investigate how fuel‐driven pH fronts can be sent out from these spheres and regulated by internal reaction networks. Membrane characteristics are installed by covering urease spheres with responsive hydrogel shells. We then encapsulate the two networks (urea‐urease and ester‐esterase) separately into different hydrogel spheres to devise communication, pattern formation and attracti…