Search results for "load"
showing 10 items of 1967 documents
Face masks effectively limit the probability of SARS-CoV-2 transmission.
2021
Masking out air sharing The effectiveness of masks in preventing the transmission of severe acute respiratory syndrome coronavirus 2 has been debated since the beginning of the COVID-19 pandemic. One important question is whether masks are effective despite the forceful expulsion of respiratory matter during coughing and sneezing. Cheng et al. convincingly show that most people live in conditions in which the airborne virus load is low. The probability of infection changes nonlinearly with the amount of respiratory matter to which a person is exposed. If most people in the wider community wear even simple surgical masks, then the probability of an encounter with a virus particle is even fur…
Is there scientific evidence of the mouthwashes effectiveness in reducing viral load in Covid-19? A systematic review.
2020
Background The aim of this research is to verify whether there is evidence in the literature regarding the decrease in viral load present in saliva after using three types of mouthwashes. Material and methods Clinical and/or in vitro experimental studies that have used mouthwashes as a form of intervention to reduce the viral load in saliva were included. Combinations of words and appropriate truncations were adapted for each of the seven selected electronic bases including grey literature. Results The selection of articles was carried out in two phases by two independent reviewers. After removing duplicate articles, 1245 references were maintained, and 2 articles were included in the Syste…
From job demands and resources to work engagement, burnout, life satisfaction, depressive symptoms, and occupational health
2016
This study investigated the cross-lagged associations between work engagement and burnout, and life satisfaction and depressive symptoms, their demands (i.e., workload) and resources (i.e., servant leadership, self-efficacy, resilience) and relationships with occupational health outcomes (i.e., recovery, number of mental health diagnoses, workaholism). This study is a part of an ongoing Occupational Health Study in which 1 415 employees (586 men, 829 women) were followed twice during two years 2011–12 through their occupational health services. The participants filled in a questionnaire on their work engagement, burnout symptoms, well-being, personal and work environmental resources and dem…
Site-specific DBCO modification of DEC205 antibody for polymer conjugation
2018
The design of multifunctional polymer-based vectors, forming pDNA vaccines, offers great potential in cancer immune therapy. The transfection of dendritic immune cells (DCs) with tumour antigen-encoding pDNA leads to an activation of the immune system to combat tumour cells. In this work, we investigated the chemical attachment of DEC205 antibodies (aDEC205) as DC-targeting structures to polyplexes of P(Lys)-b-P(HPMA). The conjugation of a synthetic block copolymer and a biomacromolecule with various functionalities (aDEC205) requires bioorthogonal techniques to avoid side reactions. Click chemistry and in particular the strain-promoted alkyne-azide cycloaddition (SPAAC) can provide the req…
[1,2,3]Triazolo[1,5-a]piridinas y compuestos relacionados : aplicaciones en química supramolecular : actividad biológica
2013
Los heterociclos nitrogenados son moléculas clave dentro de numerosos campos científicos. En concreto, los triazoles han encontrado numerosas aplicaciones en química médica como antifúngicos (fluconazol, posaconazol), antidepresivos (trazodona) o anticancerígenos (triazoloacridonas). En este contexto se decidió sintetizar nuevos derivados de [1,2,3]triazolo[1,5-a]piridinas con el fin de explorar su capacidad de interaccionar con ADN y su actividad leishmanicida y antichagásica. Con este objetivo se ha utilizado la química clásica de las triazolopiridinas (reacción de litiación regioselectiva de este heterociclo, seguida de adición de un electrófilo), para obtener nuevos derivados con estruc…
Sovraccarico e rischi da dipendenza da lavoro negli accademici italiani: un'indagine conoscitiva
2018
Negli ultimi anni in Italia si è assistito ad un cambiamento nel lavoro del docente universitario, che ha spinto ad aumentare la quota di tempo da dedicare alle diverse attività (molte delle quali inattese all'atto della assunzione) e che ha prodotto una sorta di giustificazione "culturale" di comportamenti che possono essere configurabili a margine del rischio workaholism. Esiste una ampia letteratura relativa al peso del sovraccarico lavorativo dei lavoratori del sistema dell'educazione, ed in particolare connessi al peso delle attività d'aula ed all'aumento del lavoro burocratico; le ricerche che si sono occupate della "higher education" hanno però perlopiù connesso il sovraccarico lavor…
Osseotite caricati a due mesi nei settori posteriori del mascellare superiore: controllo a 2 anni di due casi clinici
2003
Aim Acid etched surface implants determine high clinical success rates, but little information is available about early loading in the posterior region of the maxilla, area at risk of failure. The aim of this work is to present two case reports of oral rehabilitation through acid etched surface implants (Osseotite, Implant Innovations - 3i, West Palm Beach, FL) loaded two months after insertion in the posterior maxilla. Materials and methods The success of Osseotite implants was assessed 12 and 24 months after prosthetic loading according to Albrektsson et al. criteria (1986). Results No clinical or radiographic signs of implant failure were observed during the two years follow-up. Conclusi…
Want to Impact Physical, Technical, and Tactical Performance during Basketball Small-Sided Games in Youth Athletes? Try Differential Learning Beforeh…
2020
This study aimed to analyze the acute effect of small-sided games, based on differential learning, on the physical, technical, and positioning performance of young basketball players. Eight basketball players under 13 (U13) participated in this study. A total of eight sessions involving half-court small-sided games (4 sets ×
Acute Effects on Impact Accelerations Running with Objects in the Hand
2021
Amateur runners usually run carrying implements in their hands (keys, a mobile phone, or a bottle of water). However, there is a lack of literature about the effects of different handloads on impact accelerations. Thus, this study aimed to analyse the effects of carrying different objects in the hand on impact accelerations during running. Nineteen male recreational runners (age 24.3 ± 6.8 years, training volume of 25 ± 7.38 km/week) performed twenty minutes of running on a treadmill at 2.78 m/s with four different conditions: no extra weight, with keys, with a mobile phone, and with a bottle of water. Impact acceleration and spatio-temporal parameters were analysed through a wireless triax…
Optimization design process of a morphing winglet
2018
Aeronautic and aerospace engineering is recently moving in the direction of developing morphing wing devices, with the aim of making adaptable the aerodynamic shapes to different operational conditions. Those devices may be classified according to two different conceptual architectures: kinematic or compliant systems. Both of them embed within their body all the active components (actuators and sensors), necessary to their operations. In the first case, the geometry variation is achieved through an augmented classical mechanism, while in the second case the form modification is due to a special arrangement of the inner structure creating a distributed elastic hinges arrangement. Whatever is…