Search results for "load"

showing 10 items of 1967 documents

Brain atrophy evolution and lesion load accrual in multiple sclerosis: a 2-year follow-up study

2009

Background To investigate in a large cohort of patients with multiple sclerosis (MS), lesion load and atrophy evolution, and the relationship between clinical and magnetic resonance imaging (MRI) correlates of disease progression. Methods Two hundred and sixty-seven patients with MS were studied at baseline and two years later using the same MRI protocol. Abnormal white matter fraction, normal appearing white matter fraction, global white matter fraction, gray matter fraction and whole brain fraction, T2-hyperintense, and T1-hypointense lesions were measured at both time points. Results The majority of patients were clinically stable, whereas MRI-derived brain tissue fractions were signifi…

AdultMalePathologymedicine.medical_specialtyAdolescentCentral nervous systemmultiple sclerosisSeverity of Illness IndexLesion loadWhite matterCentral nervous system diseaseYoung AdultDegenerative diseaseAtrophyMultiple Sclerosis Relapsing-RemittingatrophyRisk FactorsT2 lesionsmedicinefollow upHumansAgedmedicine.diagnostic_testbusiness.industryMultiple sclerosisBrain AtrophyBrainMagnetic resonance imagingMiddle AgedMultiple Sclerosis Chronic Progressivelesion loadmedicine.diseaseMagnetic Resonance Imagingmedicine.anatomical_structureCross-Sectional StudiesLogistic ModelsNeurologymultiple sclerosiMultivariate AnalysisDisease ProgressionFemaleSettore MED/26 - NeurologiaNeurology (clinical)businessFollow-Up StudiesMRI
researchProduct

Feasibility, reproducibility, and reliability for the T*2 iron evaluation at 3 T in comparison with 1.5 T

2012

This study aimed to determine the feasibility, reproducibility, and reliability of the multiecho T * 2 Magnetic resonance imaging technique at 3 T for myocardial and liver iron burden quantification and the relationship between T * 2 values at 3 and 1.5 T. Thirty-eight transfusion-dependent patients and 20 healthy subjects were studied. Cardiac segmental and global T * 2 values were calculated after developing a correction map to compensate the artifactual T * 2 variations. The hepatic T * 2 value was determined over a region of interest. The intraoperator and interoperator reproducibility for T * 2 measurements at 3 T was good. A linear relationship was found between patients' R (1000/T * …

AdultMalePathologymedicine.medical_specialtyheartliverSensitivity and SpecificityRegion of interestmedicineHumansT*2 magnetic resonanceLiver ironRadiology Nuclear Medicine and imaging3 Tiron overloadReliability (statistics)Observer VariationReproducibilitymedicine.diagnostic_testbusiness.industryHealthy subjectsReproducibility of ResultsMagnetic resonance imagingImage EnhancementMagnetic Resonance ImagingLinear relationshipThalassemiaFemalebusinessNuclear medicineObserver variationMagnetic Resonance in Medicine
researchProduct

Hepatocellular carcinoma in patients with thalassaemia syndromes: clinical characteristics and outcome in a long term single centre experience

2010

AdultMalePediatricsmedicine.medical_specialtyCarcinoma HepatocellularIron OverloadCirrhosisThalassemiaCarcinomaHumansMedicineAgedbusiness.industryLiver NeoplasmsTransfusion ReactionCancerHematologyHepatitis CHepatitis C ChronicMiddle AgedPrognosismedicine.diseaseSurgeryHemoglobinopathyHepatocellular carcinomaThalassemiaThalassaemia hepatocellular carcinoma iron overload cirrhosis hepatitis CFemalebusinessLiver cancer
researchProduct

Potato consumption does not increase blood pressure or incident hypertension in 2 cohorts of Spanish adults

2017

5 Tablas

AdultMalePediatricsmedicine.medical_specialtyDiastoleMedicine (miscellaneous)030204 cardiovascular system & hematologyMediterranean03 medical and health sciences0302 clinical medicineAnimal scienceGlycemic loadSUN cohortmedicineHumans030212 general & internal medicineIntervention trialProspective cohort studyPotatoesGeneralized estimating equationAgedSolanum tuberosumAged 80 and overNutrition and DieteticsIncrease blood pressurebusiness.industryIncidence (epidemiology)PREDIMED studyMiddle AgedDietBlood pressureSpainHypertensionBlood pressureFemalebusiness
researchProduct

Estimating minimum adult HIV prevalence: A cross-sectional study to assess the characteristics of people living with HIV in Italy

2015

In 2012, we conducted a retrospective cross-sectional study to assess the number of people living with HIV linked to care and, among these, the number of people on antiretroviral therapy. The health authority in each of the 20 Italian Regions provided the list of Public Infectious Diseases Clinics providing antiretroviral therapy and monitoring people with HIV infection. We asked every Public Infectious Diseases Clinic to report the number of HIV-positive people diagnosed and linked to care and the number of those on antiretroviral therapy during 2012. In 2012, 94,146 people diagnosed with HIV and linked to care were reported. The majority were males (70.1%), Italians (84.4%), and aged betw…

AdultMalePediatricsmedicine.medical_specialtyImmunology; Infectious Diseases; VirologySettore MED/17 - Malattie InfettiveEpidemiologyCross-sectional studyImmunologyHuman immunodeficiency virus (HIV)MEDLINEHIV Infectionsmedicine.disease_causeAdult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV Infections; Humans; Italy; Male; Middle Aged; Prevalence; Retrospective StudiesVirologymedicinePrevalenceHumansHIV InfectionHIV prevalence ItalyRetrospective StudiesCross-Sectional StudieAdult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV Infections; Humans; Italy; Male; Middle Aged; Prevalence; Retrospective Studies; Immunology; Virology; Infectious Diseasesbusiness.industryTransmission (medicine)HIVRetrospective cohort studyMiddle AgedHiv prevalenceNorthern italyCD4 Lymphocyte CountCross-Sectional StudiesInfectious DiseasesAnti-Retroviral AgentsItalyAnti-Retroviral AgentFemalebusinessViral loadHumanDemography
researchProduct

Sexual Health in HIV-Positive Men Under Stable Antiretroviral Therapy During a 12-Month Period

2021

Sexual health is becoming increasingly important for many HIV-positive men undergoing highly effective antiretroviral therapy (ART) but remains frequently unaddressed in routine clinical consultation.To comprehensively evaluate sexual health in male patients with HIV on stable ART over a 12-month period.The prospectively registered cohort study comprising 87 HIV-positive men on stable ART (median age: 43 years) was conducted between 2011 and 2015 at a university hospital. Patients were enrolled from the outpatient infectious disease unit and underwent an extensive andrological workup to assess parameters of sexual health (questionnaires, sex hormones, ultrasound, 2-glass urine test includin…

AdultMalePediatricsmedicine.medical_specialtySexual BehaviorUrologyEndocrinology Diabetes and MetabolismSexually Transmitted Diseases030232 urology & nephrologyHIV InfectionsCohort Studies03 medical and health sciencesSemen quality0302 clinical medicineEndocrinologyClinical endpointHumansMedicineChildReproductive health030219 obstetrics & reproductive medicinebusiness.industrymedicine.diseasePsychiatry and Mental healthSexual PartnersSexual dysfunctionErectile dysfunctionReproductive MedicineCohortSexual Healthmedicine.symptombusinessViral loadCohort studyThe Journal of Sexual Medicine
researchProduct

Influence of soft tissue grafting, orofacial implant position, and angulation on facial hard and soft tissue thickness at immediately inserted and pr…

2018

Background Resorption of hard and soft tissues following immediate implant insertion is frequently reported. Data regarding the influencing factors on facial tissue thickness are rare. Purpose This retrospective study investigated the impact of connective tissue grafting, the orofacial angulation and position of immediately inserted and provisionalized implants on the facial hard and soft tissue thickness in the anterior maxilla within a 1- to 5-year follow-up. Material and methods Implants with the prerequisite of having preoperative and postoperative cone beam computed tomography (CBCT) and a follow-up of 1 to 5 years were included. Facial bone deficiencies were grafted flaplessly with au…

AdultMalePeriodontiumCone beam computed tomographyImmediate Dental Implant LoadingFacial boneAdolescentConnective tissue03 medical and health sciencesYoung Adult0302 clinical medicineAlveolar ProcessMaxillaMedicineHumansBone regenerationGeneral DentistryAgedRetrospective StudiesOrthodonticsbusiness.industryDental Implantation EndosseousMouth MucosaSoft tissue030206 dentistryCone-Beam Computed TomographyMiddle AgedResorptionDental Restoration Temporarymedicine.anatomical_structure030220 oncology & carcinogenesisFacial tissueFemaleImplantOral SurgerybusinessClinical implant dentistry and related research
researchProduct

Distinct muscle-tendon interaction during running at different speeds and in different loading conditions.

2019

The interaction between the Achilles tendon and the triceps surae muscles seems to be modulated differently with various task configurations. Here we tested the hypothesis that the increased forces and ankle joint work during running under contrasting conditions (altered speed or load) would be met by different, time-dependent adjustments at the muscle-tendon level. Ultrasonography, electromyography, kinematics, and ground reaction force measurements were used to examine Achilles tendon, gastrocnemius, and soleus muscle mechanics in 16 runners in four different running conditions, consisting of a combination of two different speeds (preferred and +20% of preferred speed) and two loading co…

AdultMalePhysiologyComputer scienceAchilles TendonRunning03 medical and health sciences0302 clinical medicinePhysiology (medical)medicineHumansMuscle SkeletalBiological sciencesGaitUltrasonographyLoad carriageAchilles tendonbusiness.industryWork (physics)030229 sport sciencesStructural engineeringmusculoskeletal systemTendonBiomechanical Phenomenamedicine.anatomical_structurebusinessMuscle architecture030217 neurology & neurosurgeryAnkle JointMuscle ContractionJournal of applied physiology (Bethesda, Md. : 1985)
researchProduct

Mechanical behavior of the quadriceps femoris muscle tendon unit during low-load contractions

2008

We examined the relationships between morphology and muscle-tendon dynamics of the quadriceps femoris muscle of 11 men using velocity-encoded phase-contrast magnetic resonance imaging (MRI). Thigh muscle electromyography and joint range of motion were first measured outside the MRI scanner during knee extension-flexion tasks that were performed at a rate of 40 times/min with elastic bands providing peak resistance of 5.2 kp (SD 0.4) to the extension. The same movement was repeated inside the MRI scanner bore where tissue velocities and muscle morphology were recorded. The average displacement in the proximal and distal halves of the rectus femoris and vastus intermedius aponeuroses was dif…

AdultMalePhysiologyStrain (injury)ThighTendonsPhysiology (medical)medicineHumansLow loadKneeAponeurosisMuscle SkeletalLegmedicine.diagnostic_testElectromyographybusiness.industryMagnetic resonance imagingAnatomymedicine.diseaseMagnetic Resonance ImagingQuadriceps femoris muscleBiomechanical PhenomenaTendonmedicine.anatomical_structureThighmedicine.symptombusinessMuscle ContractionMuscle contractionJournal of Applied Physiology
researchProduct

Identification of possible risk factors for alcohol use disorders among general practitioners in Rhineland-Palatinate, Germany

2012

QUESTIONS UNDER STUDY Research on alcohol use disorders among physicians has been scarce in Germany. The aim of our study was to identify possible risk factors for alcohol use disorders among general practitioners (GPs) working in the outpatient sector in the federal German state of Rhineland-Palatinate (RP). METHODS An anonymous survey was carried out between June and July 2009. 2,092 practice-based GPs in the federal German state of RP were asked to take part in the cross-sectional study via postal mail. The CAGE screening tool was used in its German version (CAGE-G) to screen for alcohol use disorders (AUD). Moreover, possible risk factors such as work stress (effort-reward imbalance), s…

AdultMaleRelaxationmedicine.medical_specialtyAlcohol Drinkingmedia_common.quotation_subjectWorkloadLogistic regressionJob SatisfactionGermanSex FactorsGeneral PractitionersRisk FactorsGermanyPrevalenceHumansPersonalityMedicineScreening toolPsychiatrymedia_commonResponse rate (survey)business.industryType D personalityAge FactorsGeneral MedicineMiddle AgedResilience PsychologicalHealth Surveyslanguage.human_languageAlcoholismIdentification (information)Cross-Sectional StudiesLogistic ModelslanguageFemalePsychological resiliencebusinessStress PsychologicalPersonalitySwiss Medical Weekly
researchProduct