6533b82bfe1ef96bd128d69e
RESEARCH PRODUCT
Estimating minimum adult HIV prevalence: A cross-sectional study to assess the characteristics of people living with HIV in Italy
Margherita BussoTullio PrestileoErmenegildo FrancavillaMarco AnselmoFrancesco MontellaEvangelista SagnelliTeresa SantantonioMassimo GalliMarcello SaittaGiuseppe FotiCecilia GuarigliaFranco BaldelliSimona Di GianbenedettoPierluigi VialeFrancesco CastelliAntonella D'arminio MonforteAngelo PanGabriella D’ettoreMaria DorrucciSalvatore BrunoTiziana QuirinoMariangela RaimondoAlessandro BartoloniVinicio ManfrinGiovanni MazzarelloEugenio MantiaRaffaele PempinelloAntonio TraversoBarbara SuligoiFabio BullaPietro MesinaAlessia ZoncadaGianfranco OrofinoOliviero BoscoGianmichele MoiseAngelo Salomone MegnaRoberto FerrettoMauro ValleManuela ColafigliClaudio PaternosterS. ArtioliGiovanni RiccioStefania BernardiGrossi PaoloMilena ZoppiSebastiano MaiuzzoGiorgio PerboniSauro TiniGiuseppe FerreaNicoletta LadisaEnzo M. FarinellaDaniela FrancisciDino SgarabottoRoberto MonarcaEnzo PetrelliA. FrancoIzzo CmPietro BellissimaFrancesco OrtuLaura SighinolfiAntonio ChirianniFilippo BartalesiGiulio De StefanoClaudia ColombaLaura CamoniSalvatore GalvagnaBenedetto Maurizio CelesiaAndrea PetrucciCamillo BarettiPierluigi BrugnaroFederica PolettiMaurilio ChimentiCamilla AjassaMario FalcianoRosaria La SalaSauro LuchiV. PortelliAnnamaria Degli AntoniFrancesco MazzottaGiuliano ZuccatiVincenzo ColangeliErcole ConciaGiordano MadedduMaria Cristina SalfaFrancesca CattelanNicola AconeVincenza RegineOlivia BargiacchiMaurizio De MartinoF. PaolettiGiovanni CassolaGiuliano SchettinoCarlo De StefanoEnza AnzaloneD. AquiliniGiacomo MagnaniVanni BorghiRoberta GastaldiAlessandra GovoniCristina RossiRita ConsoliniGioacchino AngaranoGloria TalianiTommaso FontanaSergio Lo CaputoDavide VitulloPierpaolo CongedoEmanuela VaccherPaolo ViganòMaria Stella MuraClaudio CancellieriEnrico GirardiFrancesca SavalliCecilia FicoAnna Maria CattelanAlessandro ChioderaRenzo ScaggianteP. OsimaniCaterina BramatoNicola PietrosilloGiovanna D'alessioSalvatore BonfanteVincenzo VulloAndrea GoriMargherita DalessandroDomenico LucchinoMassimo DeseracaPaolo TundoAlfredo PennicaM. PaoloniAntonella CastagnaNicola SerraoPaolo CostaFranco MarranconiMassimo VillaPietro FilippiniMaurizio SettiEligio PizzigalloMarco TinelliMauro MarchiliDomenico SantoroCesira NencioniPiera DonesVincenzo RendaAlberto GiannettiDomenico La RovereNicoletta DorigoniGuido PalamaraAngelo IodiceClara GabianoPeter MianLuigi GuarnieriAndrea De LucaNicola TripodiGiovanni CristinaGiustino ParrutiMaria MontroniLoredana PalvariniMarco RizziBenvenuto GrisorioCorrado CatalaniPaolo Emilio ManconiJacopo VecchiettTiziana CarliRiccardo IapoceMassimo AndreoniAdriano LazzarinGiorgetta Casalino FinocchioD SacchiniMario GobberSpartaco SaniMarco CampusRosario La RosaMaurizio MazzeoStefano BonoraMichele TrezziPaolo BassiAngela La GalaAlessandro GrimaldiDante Di GiammartinoGuido LeoGaetano FiliceAntonio SalvoPaolo BonfantiChiara PasqualiniMarcello TavioLuca ButiniN. AbresciaAngela LinzaloneGianpaolo Natalini RamponiPierangelo RoverePiero CorteseDario BartolozziF. RestaMiriam LichtnerLoredana SarmatiFrancesco CesarioRenato F. FrongilloIvano MezzaromaCarlo FerrariLorenzo MinoliPaola Di StefanoLucina TitoneRosa BoncoraglioMariana FarengaGiuliano RizzardiniStefano Aviani BarbacciAndrea GiacomettiAndrea AntinoriAntonio CateriniConsuelo GeraciPiergiorgio ChiriacòLucio CoscoClaudio ViscoliAlfredo ScalziniSandro PigaMassimo ArlottiCecilia OcchinoRoberto LuzzatiPaola SabbatiniGuglielmo BorgiaUmberto TirelliAntonio DaviLetizia CristianoCristina MussiniRoberto CaudaPatrizio VittucciB. SalassaMarco LibanoreMaria Pina SciottiIsa PicernoMatteo BassettiBenedetto CaroleoOswald MolingDanilo TacconiMassimo Puotisubject
AdultMalePediatricsmedicine.medical_specialtyImmunology; Infectious Diseases; VirologySettore MED/17 - Malattie InfettiveEpidemiologyCross-sectional studyImmunologyHuman immunodeficiency virus (HIV)MEDLINEHIV Infectionsmedicine.disease_causeAdult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV Infections; Humans; Italy; Male; Middle Aged; Prevalence; Retrospective StudiesVirologymedicinePrevalenceHumansHIV InfectionHIV prevalence ItalyRetrospective StudiesCross-Sectional StudieAdult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV Infections; Humans; Italy; Male; Middle Aged; Prevalence; Retrospective Studies; Immunology; Virology; Infectious Diseasesbusiness.industryTransmission (medicine)HIVRetrospective cohort studyMiddle AgedHiv prevalenceNorthern italyCD4 Lymphocyte CountCross-Sectional StudiesInfectious DiseasesAnti-Retroviral AgentsItalyAnti-Retroviral AgentFemalebusinessViral loadHumanDemographydescription
In 2012, we conducted a retrospective cross-sectional study to assess the number of people living with HIV linked to care and, among these, the number of people on antiretroviral therapy. The health authority in each of the 20 Italian Regions provided the list of Public Infectious Diseases Clinics providing antiretroviral therapy and monitoring people with HIV infection. We asked every Public Infectious Diseases Clinic to report the number of HIV-positive people diagnosed and linked to care and the number of those on antiretroviral therapy during 2012. In 2012, 94,146 people diagnosed with HIV and linked to care were reported. The majority were males (70.1%), Italians (84.4%), and aged between 25 and 49 years (63.4%); the probable route of transmission was heterosexual contact in 37.5% of cases, injecting drug use in 28.1%, and male-to-male contact in 27.9%. Among people in care, 20.1% had less than 350 CD4 cells/μl, 87.6% received antiretroviral therapy, and among these, 62.4% had a CD4 cell count higher than 350 cells/μl. The overall estimated prevalence of individuals diagnosed and linked to care in 2012 in Italy was 0.16 per 100 residents (all ages). Adding the estimated proportion of undiagnosed people, the estimated HIV prevalence would range between 0.19 and 0.26 per 100 residents. In Italy, the majority of people diagnosed and linked to care receive antiretroviral therapy. A higher prevalence of individuals diagnosed and linked to care was observed in Northern Italy and among males. More information for developing the HIV care continuum is necessary to improve the entire engagement in care, focusing on test-and-treat strategies to substantially reduce the proportion of people still undiagnosed or with a detectable viral load.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-01 |