Search results for "location"
showing 10 items of 1480 documents
Ethics of ageing
2021
In the coming decades the world will face an unprecedented change in the composition of its population that will reshape and challenge social and political systems. Unique in human history, this change, unlike most of the changes that societies will experience during the next 50 years, is largely predictable. Population aging, with advances in medical technology, ensures that the allocation problem will continue to affect societies as far as one can see into the future. Currently this issue has mostly been formulated in terms of challenges created by increasing costs, and the focus has been squarely on life-prolonging treatments. In doing so, we’re missing many other important issues which …
The peer review game: an agent-based model of scientists facing resource constraints and institutional pressures
2018
This paper looks at peer review as a cooperation dilemma through a game-theory framework. We built an agent-based model to estimate how much the quality of peer review is influenced by different resource allocation strategies followed by scientists dealing with multiple tasks, i.e., publishing and reviewing. We assumed that scientists were sensitive to acceptance or rejection of their manuscripts and the fairness of peer review to which they were exposed before reviewing. We also assumed that they could be realistic or excessively over-confident about the quality of their manuscripts when reviewing. Furthermore, we assumed they could be sensitive to competitive pressures provided by the ins…
The effect of agglomeration economies and geography on the survival of accommodation businesses in Sicily
2021
The study explores the geographical pattern of the accommodation industry in the Italian insular region of Sicily, focusing on the determinants of the risk of market exit. We adopt a standard framework of business survival analysis where agglomeration economies play an important role. We then extend the analysis by considering the role of geography to explore whether the risk of market exit depends on nearness to desirable amenities. The geography is here measured by the distance from the coast and the altitude of the place where the firm is located. When we look at the entire population of accommodation firms that started between 2010 and 2014, we find evidence that the risk of failure inc…
Multiplicity results for a class of asymmetric weakly coupled systems of second order ordinary differential equations
2005
We prove the existence and multiplicity of solutions to a two-point boundary value problem associated to a weakly coupled system of asymmetric second-order equations. Applying a classical change of variables, we transform the initial problem into an equivalent problem whose solutions can be characterized by their nodal properties. The proof is developed in the framework of the shooting methods and it is based on some estimates on the rotation numbers associated to each component of the solutions to the equivalent system.
Karyotype Abnormalities in a Variant Chinese Hamster Cell Line Resistant to Methyl Methanesulphonate
2004
A variant cell population, isolated from V79-CI 3 Chinese hamster cells after two consecutive treatments with methyl methanesulphonate (MMS), was found to be highly resistant to killing by this alkylating agent. The resistant cell line was cytogenetically characterized both by the presence of a stable translocation involving metacentric chromosome 2 and acrocentric chromosome 6 and by a supernumerary chromosome originated by the duplication of a small telocentric chromosome. This cell population also showed a transient transformed phenotype, seen as formation of transformed foci containing cells with high chromosomes counts and multiple chromosomal aberrations. As MMS-resistance and karyoty…
La pandemia da COVID-19: mutamento e persistenze
2022
L’analisi dei documenti prodotti in Italia sul tema dell’accesso alle terapie intensive durante la pandemia da COVID-19 indica che la riflessione sulle questioni di accesso alle risorse drammaticamente limitate nel nostro Paese è ancora molto acerba e meriterebbe lavori di indagine più accurata e approfondita con un contributo multidisciplinare. Bioetica. Rivista interdisciplinare ha contribuito alla maturazione e alla crescita delle conoscenze in questo ambito, con la pubblicazione di diversi articoli. Tale apertura verso i temi di giustizia distributiva mostra la capacità della rivista di cogliere e affrontare i temi emergenti nel dibattito bioetico italiano, mostra il suo sapere essere “…
Selective erasure of a fear memory
2009
International audience; Memories are thought to be encoded by sparsely distributed groups of neurons. However, identifying the precise neurons supporting a given memory (the memory trace) has been a long-standing challenge. We have shown previously that lateral amygdala (LA) neurons with increased cyclic adenosine monophosphate response element-binding protein (CREB) are preferentially activated by fear memory expression, which suggests that they are selectively recruited into the memory trace. We used an inducible diphtheria-toxin strategy to specifically ablate these neurons. Selectively deleting neurons overexpressing CREB (but not a similar portion of random LA neurons) after learning b…
Sociāla maršruta aplikācija ar karšu integrāciju
2017
Kvalifikācijas darbā tiek aprakstīta sociāla rakstura maršrutu lietotne “Social trails”, kas ir paredzēta viedtālruņiem ar Android operētājsistēmu. Lietotne paredzēta, lai tās lietotāji varētu rīkot izklaidējošus pārgājienus un iepazīt citus tās lietotājus. Tam, lai pārgājieni būtu būtiski konkrētajam lietotājam, applikācija tos rāda Google Maps, vadoties pēc ierīces atrašanās vietas.
Effects of a glyphosate-based herbicide on survival and oxidative status of a non-target herbivore, the Colorado potato beetle (Leptinotarsa decemlin…
2018
Abstract Glyphosate is the globally most used herbicide against a wide range of weeds. Glyphosate has been considered safe to animals as it mainly targets physiological pathways in plants. However, recent toxicological studies have revealed that glyphosate can cause various toxic effects also on animals. In this study, we investigated the direct toxic effects of a glyphosate-based herbicide (GBH, Roundup® Bio) on 1) survival and 2) oxidative status of a non-target herbivore by using Colorado potato beetles (Leptinotarsa decemlineata), originating from Poland and USA, as model species. Larvae were randomly divided into three groups: 1) high concentration (100% Roundup Bio, 360 g/l), 2) low c…
Response of bird predators for female wood tiger moth chemical defences
2018
Multiple behavioural responses of blue tit predators to the defence fluids of wood tiger moth (Arctia plantaginis) females that were either food deprived or fed ad libitum during development.