Search results for "lost"
showing 10 items of 626 documents
Frontispiece: Positive Allosteric Control of Guests Encapsulation by Metal Binding to Covalent Porphyrin Cages
2019
ChemInform Abstract: Polycondensed Nitrogen Heterocycles. Part 17. Isoxazolo(4,3-d)pyrazolo-(3,4-f)(1,2,3)triazepine. A New Ring System.
1988
The title compounds were prepared by nitration of compounds 2, reduction of the dinitro derivatives 4 and diazotization of the diamino derivatives 6 followed by an intramolecular coupling reaction. Compound 4a showed good activity against Salmonella cholerasuis and Clostridium perfringens bacteria.
Ad Philostrati Vitam Apolloni
2004
Lesson 7: Enzymatic kinetics
2022
Este documento ha sido revisado por el Servicio de política Linguística. Su labor ha sido muy importante para la correción del documento. Este documento contiene un pdf con las diapositivas utilizadas en el tema 7 de los alumnos de primero del Grado de Medicina, dentro de la asignatura Bioquímica y Biología Molecular. Se describen los conceptos de cinética enzimática y la ecuación de Michaelis Menten. También se describe el fenómeno de cooperatividad y el alosterismo enzimático. This document contains a pdf doc with the slides used in lesson 7 for first-year students of the Medicine Degree, within the Biochemistry and Molecular Biology subject. This lesson describes the concepts of enzyme k…
Étude paléoenvironnementale et paléoclimatique multiproxiesdes bassins fini-carbonifères à permiens du N-E duMassif central.
2021
National audience; Les bassins intracontinentaux fini-carbonifères à permiens d'Autun et de Decize-LaMachine (NE du Massif central) ont fait l'objet d'un travail de thèse s'appuyant sur denombreuses méthodes d'analyse appliquées à haute résolution sur des données deforages et quelques coupes.Les interprétations des résultats sédimentologiques (faciès, diagraphies, sismique), destratigraphie séquentielle, de géochimie et isotopie organique (carbone et azote) et deminéralogie ont permis de reconstituer de la manière la plus précise possible l'évolutiondes environnements sédimentaires de ces bassins dans l'espace et au cours du temps.Il en ressort que les deux bassins étudiés dominés par des d…
Inter- and Intraobserver Variation in the Assessment of Preoperative Colostograms in Male Anorectal Malformations: An ARM-Net Consortium Survey
2020
Aim:Male patients with anorectal malformations (ARM) are classified according to presence and level of the recto-urinary fistula. This is traditionally established by a preoperative high-pressure distal colostogram that may be variably interpreted by different surgeons. The aim of this study was to evaluate the inter- and intraobserver variation in the assessment by pediatric surgeons of preoperative colostograms with respect to the level of the recto-urinary fistula. Materials and Methods:Sixteen pediatric surgeons from 14 European centers belonging to the ARM-Net Consortium twice scored 130 images of distal colostograms taken in sagittal projection at a median age of 66 days of life (rang…
Diplostomiasis ( Diplostomum spathaceum and related species).
2020
This book chapter describes various aspects of diplostomiasis caused by Diplostomum spathaceum: diagnosis, epidemiology, life cycle, transmission, developmental stages, population dynamics, effects of climate change on parasite distribution, and disease control and prevention. peerReviewed
Informaation piilottaminen draamasarjassa Lost
2018
Tarkastelen tässä tutkielmassa Lost-draamasarjassa (USA 2004–2010) esiintyvää informaation piilottamista. Esittelen sarjasta poimimieni esimerkkien avulla niitä kerronnan keinoja, joiden avulla sarja viivyttää tiedon paljastamista katsojalle. Pohdin myös piilottamisen ongelmia sekä etuja. In this thesis I examine the hiding of information in the drama series Lost (USA 2004–2010). With examples from Lost I explain the narrative devices used in the series to delay the disclosure of information. I also contemplate the pros and cons of such hiding.
Activation and Inactivation of Tetanus Toxin in Chromaffin Cells
1993
Tetanus toxin is produced by Clostridium tetani as a single chain, almost non-toxic, protein with a molecular weight of approximately 150.000 representing 1315 amino acids. Bacterial proteases cleave the molecule between positions A 457 and S 458 (extracellular activation), yielding a heavy chain (MW 100.000) and a light chain (MW 50.000) tetanus toxin (HC-TeTx, LC-TeTx). Both chains remain connected to each other by a disulphur bond between positions C 439 and C 467 (Dichain-TeTx)1. The cleavage or nicking dramatically increases the biological activity2. HC-TeTx is involved in binding DC-TeTx to gangliosides lodged in the plasma membrane, which is a prerequisite for incorporation into the …
A potential role for water in the modulation of oxygen-binding by tarantula hemocyanin
2003
Hemocyanin from the tarantula Eurypelma californicum is a large respiratory protein with an exceptional high cooperativity. In contrast to hemocyanins from other species, no physiological allosteric effectors other than protons have been identified so far for this 24-meric oligomer. Here we report for the first time the mediating effects of water activity on the oxygen binding properties of a hemocyanin. Oxygen binding curves were measured in presence of several concentrations of glycine and sucrose since both substances reduce water activity. A pronounced shift of the p(50) was observed in both cases but in different directions: adding sucrose shifts the p(50) towards lower values whereas …