Search results for "lucid"

Papillote and Piopio:DrosophilaZP-domain proteins required for cell adhesion to the apical extracellular matrix and microtubule organization

2005

Adhesion between epithelial cells and extracellular substrates is normally mediated through basal adhesion complexes. However, some cells also possess comparable junctions on their apical surface. Here, we describe two new Drosophila proteins, Piopio and Papillote, that are required for the link between the apical epithelial surface and the overlying apical extracellular matrix (aECM). The two proteins share a zona pellucida (ZP) domain with mammalian aECM components, including the tectorins found in the vertebrate inner ear. Tagged versions of both proteins localized to the apical epithelial surface. Mutations in piopio, papillote and dumpy (another gene encoding a ZP-domain protein) cause…

Zinc-positive presynaptic boutons of the rabbit hippocampus during early postnatal development

1998

Abstract The evolution of vesicular zinc-containing boutons in the developing rabbit hippocampus has been studied during early postnatal life using the selenite–Danscher histochemical method. By P3, large immature mossy fiber boutons with labeled synaptic vesicles were seen in the hilus of the dentate gyrus and in the stratum lucidum of the CA3–CA4 hippocampal areas. After P5, smaller boutons with labeled vesicles were identified in the stratum oriens and stratum radiatum of all hippocampal areas, and even transiently in the stratum lacunosum of P6 animals. Vesicular zinc-containing boutons increased in number and underwent ultrastructural maturation; light microscope densitometric–volumetr…

Role of the peripheral endocannabinoid system in the obesity-linked metabolic disorders genesis : Involvement of adipose tissue derived endocannabino…

2021

Obesity is a pathology characterized by an excess of adipose tissue (AT) whose functions may be altered. Interestingly, strong evidence suggests that metabolic dysregulations linked to obesity is associated with an hyperactivation of the endocannabinoid system (ECS) in several organs including AT. This system, composed of cannabinoid receptors (CB1R and CB2R), their endogenous ligands (EndoCannabinoids - ECs) and their biosynthetic and degrading enzymes, is expressed both in the central nervous system and in various peripheral tissues.CB1R blockade with Rimonabant, the first antagonist marketed in 2006, has proven to be an effective therapeutic approach by reducing food intake, body mass an…

Effects of natural extracts in the treatment of oral ulcers: A systematic review of evidence from experimental studies in animals

2021

Background To evaluate the clinical and histopathological effects of natural extracts in the treatment of oral ulcers induced in animal experimental models. Material and methods We carried out a search in the Medline, Scopus, WoS and Embase databases from the start of the databases to December 2020, and also made a manual search of the references. The search and selection were carried out by two researchers independently. The inclusion criteria were: experimental studies in animal models, in english, which complied with the study object. Results A total of 705 articles were identified. After selection by title, abstract and full text, 19 articles were finally included. Natural extracts of J…

Effect of the Converging Pipe on the Performance of a Lucid Spherical Rotor

2018

Lucid spherical rotor is a cross-flow rotor developed to be installed within a pipeline. The purpose of installing this type of rotor is to collect excess energy available in gravity-fed water pipelines. In order to enhance the efficiency of the rotor which is installed in a channel, this paper aims to study the performance of Lucid spherical rotor with converging pipe. Numerical investigations were carried out to analyze the effect of the converging pipe on the performance of the rotor. Numerical simulations have been carried out using the unsteady Reynolds-averaged Navier–Stokes equations in conjunction with the realizable $$k-{\varepsilon }$$ turbulence model. The validation of the numer…

Sequence evolution, processing, and posttranslational modification of zonadhesin D domains in primates, as inferred from cDNA data

2005

Zonadhesin is a mammalian transmembrane sperm ligand. Precursor zonadhesin essentially consists of MAM (meprin/A5 antigen/mu receptor tyrosine phosphatase) domains, a mucin-like repeat, and D domains (homologous to von Willebrand D). Recent immunovisualization and binding assays indicate that zonadhesin D domains 1–3 bind postacrosomally to the zona pellucida. This feature has attracted considerable interest in the evolution of zonadhesin and its possible biological and biomedical implications. Previous molecular evolutionary analyses, however, were confined to cDNA sequences of only few distantly related species. Moreover, except for rabbit and pig, little is known about zonadhesin’s proce…

Quantum Chemical Calculations Predict the Diphenyl Diuranium Compound [PhUUPh] To Have a Stable1Ag Ground State

2006

Misfolded vasopressin V2 receptors caused by extracellular point mutations entail congenital nephrogenic diabetes insipidus.

2000

Vasopressin V2 receptor mutants from three different patients with congenital nephrogenic diabetes insipidus phenotypes were investigated after expression in COS cells. The amino acid exchanges within the human V2 receptor are located in the second extracellular loop (T204N, Y205C and V206D). Confocal microscopy showed that all receptor mutants were strongly expressed but mainly located within the cell. Residual binding capacity for the antidiuretic hormone arginine vasopressin (AVP) could only be detected for the T204N mutant and was 10-fold lower than for the wild-type receptor. Stimulation of transfected cells with 1 microM AVP showed that the T204N mutant was able to activate the adenyl…

Les colloïdes solubles du vin de champagne. Relation avec le « remuage »

1978

<p style="text-align: justify;">Dans ce travail on étudie un échantillonnage de vins de champagne, en vue d'établir une relation entre leur composition en colloïdes et la facilité du « remuage ».</p><p style="text-align: justify;">Après champagnisation, les teneurs en colloïdes totaux sont toujours supérieures à celles des vins tranquilles correspondants. Plus la durée de clarification et de remuage est grande plus la teneur en colloïdes est élevée.</p><p style="text-align: justify;">Le fractionnement des colloïdes glucidiques solubles, en quatre fractions, sur Sépharose 6 B montre que celle de plus haut poids moléculaire a l'influence la plus directe sur les d…

Integrazione di celle solari di terza generazione nel vetromattone per la realizzazione di involucri edilizi traslucidi fotovoltaici

2013

L’integrazione di celle solari di terza generazione - Dye-sensitised Solar Cells (DSSC) - nel vetromattone consente di ottenere un prodotto edilizio in grado di generare energia pulita, personalizzabile in termini di colore, livelli di trasparenza e fi niture, adatto alla realizzazione di componenti edilizi fotovoltaici, traslucidi e multifunzionali, facilmente integrabili nelle chiusure degli edifi ci per la costruzione di involucri edilizi energeticamente effi cienti ed attivi anche in contesti climatici avversi, quali possono essere quelli del Mediterraneo e delle aree subtropicali. L’articolo illustra 4 differenti ipotesi di integrazione delle DSSC nel vetromattone fornendo, per ciascun…