Search results for "lucid"

Impact du système endocannabinoïdien sur la physiologie de l'obésité : effets de l'antagonisme des récepteurs CB1 sur le métabolisme glucido-lipidiqu…

2010

The endocannabinoïd system (ECS) is involved in many biological functions such as regulation of energy metabolism. Recently, several studies have shown an association between obesity and ECS overactivity. In addition, specific CB1R antagonists such as Rimonabant (SR141716) improved metabolic parameters in obese patients essentially through inactivation of central CB1R. However, peripheral CB1R inactivation could also contribute to the improvement of these parameters and it is this notion that we have studied. To this purpose, we tested the effects of SR141716 on obese mice in order to establish relationships between the ECS activity and lipid metabolism by looking more specifically to its r…

Burvja māceklis: apzinātās sapņošanas māksla. Sapņošana kā dzīves atkārtošana modernā pasaulē

2021

Šī pētījuma mērķis ir interpretēt un analizēt specifisku tiešsaistes izglītošanos, kuras nolūks ir privāta dalībnieku apmācība par apzinātību miega laikā. Pētījums koncentrējas uz izpratni pat to, ko apzinātība nozīmē aizrautīgiem sapņotājiem, kāda ir šīs pieredzes loma ikdienas dzīvē, un kā atšifrējams virzītājspēks, kas nosaka priekšrokas došanu un apņemšanos šādi sapņot. Es cenšos pētīt apzināto sapņošanu, apvienojot naratīvas izpausmes, retorikas, radošu metaforu un cilvēka kapitāla un iztēles pārpilnības perspektīvas. Saskaņā ar noteikto četrdaļīgo shēmu, es grupēju centrālās tēmas, kas rodas no pastāvošās spriedzes tajā, kas tiek uzskatīts par apzinātību. Šīs tēmas ir: sapņotāju tiekš…

Tanzawaic acids I-L: Four new polyketides from Penicillium sp. IBWF104-06.

2014

Four new polyketides have been identified in culture filtrates of the fungal strain Penicillium sp. IBWF104-06 isolated from a soil sample. They are structurally based on the same trans-decalinpentanoic acid skeleton as tanzawaic acids A–H. One of the new compounds was found to inhibit the conidial germination in the rice blast fungus Magnaporthe oryzae at concentrations of 25 μg/mL.

Carbohydrates in plant immunity and plant protection: roles and potential application as foliar sprays.

2014

International audience; Increasing interest is devoted to carbohydrates for their roles in plant immunity. Some of them are elicitors of plant defenses whereas other ones act as signaling molecules in a manner similar to phytohormones. This review first describes the main classes of carbohydrates associated to plant immunity, their role and mode of action. More precisely, the state of the art about perception of "PAMP, MAMP, and DAMP (Pathogen-, Microbe-, Damage-Associated Molecular Patterns) type" oligosaccharides is presented and examples of induced defense events are provided. A particular attention is paid to the structure/activity relationships of these compounds. The role of sugars as…

SF002-96-1, a new drimane sesquiterpene lactone from an Aspergillus species, inhibits survivin expression

2013

Survivin, a member of the IAP (inhibitor of apoptosis) gene family, is overexpressed in virtually all human cancers and is functionally involved in the inhibition of apoptosis, regulation of cell proliferation, metastasis and resistance to therapy. Because of its upregulation in malignancy, survivin has currently attracting considerable interest as a new target for anticancer therapy. In a screening of approximately 200 strains of imperfect fungi for the production of inhibitors of survivin promoter activity, a new drimane sesquiterpene lactone, SF002-96-1, was isolated from fermentations of an Aspergillus species. The compound inhibited survivin promoter activity in transiently transfected…

Isolierung und Charakterisierung eines Dihydroflavonols bei dem Laubmoos Georgia pellucida (L.) Rabh

1977

Summary By means of paper chromatography a dihydroflavonol was isolated from the methanolic extract of the moss Georgia pellucida and partially characterized. It has the chromatographic and spectral characteristics of a 5-deoxydihydroflavonol glycoside with B-ring orthodihydroxyl group.

A new member of the fusaricidin family – structure elucidation and synthesis of fusaricidin E

2017

Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the suggested stereochemistry. The synthesis was based on a new strategy which includes an efficient access to the 15-guanidino-3-hydroxypentadecanoyl (GHPD) side chain from erucamide.

Ganoderma lucidum (Curt.: Fr.) Karst. – health-promoting properties. A review

2015

Summary This paper presents the characteristics of the species Ganoderma lucidum in terms of health-promoting properties. This species is rare in Poland, and is subject to strict protection. Reishi is classified as a medicinal mushroom which fruiting bodies are characterized by a content of active substances with diverse positive effects on human health. G. lucidum is particularly rich source of bioactive compounds, which are obtained from fruiting bodies, mycelium and spores of this species. The therapeutic effect of G. lucidum extracts has been demonstrated in many scientific studies. The most important pharmacological and physiological effects include: immunomodulatory, anti-cancer, anti…

Halogen Bonds in Square Planar 2,5-Dihalopyridine-Copper(II) Bromide Complexes

2018

Comment on "Crystallographic Snapshot of an Arrested Intermediate in the Biomimetic Activation of CO2"

2015

Out of focus: A recent Communication published in this journal describes the synthesis of [nBu4N]HCO3. The authors performed a single-crystal X-ray study that revealed a putative species described as an incipient hydroxide ion engaging in a long, and presumably weak, interaction with CO2. Our recent exploration of the coordination chemistry of CO2 with small ions leads us to believe that such an exceptional bonding situation is unlikely. Instead, we argue that the crystal structure is that of [nBu4N]O2CCH3 and therefore not representative of the bulk powder from the synthesis. peerReviewed