Search results for "m-RNA"

showing 2 items of 2 documents

Adverse Reactions to Anti-SARS-CoV-2 Vaccine: A Prospective Cohort Study Based on an Active Surveillance System

2022

To date, Coronavirus disease (COVID-19) has caused high morbidity and mortality worldwide. To counteract the pandemic scenario, several vaccines against the etiological factor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were developed and tested. At the end of December 2020, BNT162b2 (Comirnaty, Pfizer-BioNTech) was the first and only authorized vaccine in Italy for selected categories, such as healthcare workers, fragile patients and people aged over 80 years old. To master our knowledge about BNT162b2 adverse reactions (ARs), an active surveillance system based on instant messaging was realized for voluntary participants who had been vaccinated at COVID-19 Vaccination …

PharmacologySARS-CoV-2Immunologyadverse reactionactive surveillance systemadverse reaction; vaccine; coronavirus; SARS-CoV-2; m-RNA; female; young people; active surveillance systemyoung peoplecoronavirufemaleInfectious DiseasesvaccineDrug DiscoveryPharmacology (medical)m-RNAVaccines
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Allergy to Polyethilenglicole of Anti-SARS CoV2 Vaccine Recipient: A Case Report of Young Adult Recipient and the Management of Future Exposure to SA…

2021

The main contraindication to the anti-SARS CoV2 vaccine is an anaphylactic reaction to a vaccine component. The need to vaccinate allergic people who are at higher risk can be of public health interest and this report shows a case of an allergic reaction to PEG of a HCW who had received the first dose of anti-SARS CoV2 vaccine. For 5 h after the administration of the vaccine, she had the appearance of erythematous spots on the face and neck, and a feeling of a slurred mouth and hoarseness. In order to treat the event, she was administered 8 mg intravenous dexamethasone, 1 vial intravenous chlorphenamine maleate, 250 mL intravenous 0.9% NaCl, and conventional oxygen therapy (2 L/min) with co…

medicine.medical_specialtyAllergyImmunologyadverse reactionCase ReportVial03 medical and health sciences0302 clinical medicineInternal medicinevaccineDrug DiscoverymedicineanaphylaxisPharmacology (medical)030212 general & internal medicineAdverse effectContraindicationDexamethasonePharmacologym-RNA vaccinebusiness.industrySARS CoV2Rmedicine.diseasePEGAdverse reaction Anaphylaxis Basophil activation test Contraindica-tion M-RNA vaccine PEG SARS CoV2 VaccineVaccinationInfectious Diseases030228 respiratory systembasophil activation testMedicinebusinessAnaphylaxisAdverse drug reactioncontraindicationmedicine.drugVaccines
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