Search results for "malattie"

showing 10 items of 1963 documents

Exhaled nitric oxide is associated with cyclic changes in sexual hormones

2013

Abstract Background We hypothesized that changes in the levels of sexual hormones during the menstrual cycle influence the concentration of nitric oxide in the exhaled air (FeNO) and alveolar exhaled nitric oxide (CANO). Methods Twelve healthy, non allergic women in their reproductive age (age range 25–37 years) were recruited. Subjects were studied, on alternate days, over the course of their menstrual cycle. At each visit, measurements of FeNO and CANO were performed. Progesterone and 17-β-estradiol concentrations were measured in salivary samples. Results Eight subjects completed the study. The levels of FeNO and CANO were 13 ± 4.7 pbb and 3.5 ± 1.9 pbb, respectively (mean ± SD). The mea…

AdultPulmonary and Respiratory Medicinemedicine.medical_specialtymedia_common.quotation_subjectReproductive ageBronchiSettore MED/10 - Malattie Dell'Apparato RespiratorioNitric OxideNitric oxidechemistry.chemical_compoundsexual hormonesInternal medicinemedicineHumansPharmacology (medical)SalivaGeneralized estimating equationMenstrual cycleMenstrual CycleProgesteronemedia_commonEstradiolbusiness.industryBiochemistry (medical)GenderBiomarkerHormonesSexual hormonesPulmonary AlveoliEndocrinologychemistryBreath TestsNon allergicExhaled nitric oxideAirway inflammation; Biomarker; Gender; Hormones; Adult; Breath Tests; Bronchi; Estradiol; Female; Humans; Menstrual Cycle; Nitric Oxide; Progesterone; Pulmonary Alveoli; Saliva; Pulmonary and Respiratory Medicine; Pharmacology (medical); Biochemistry (medical)FemalebusinessHormoneAirway inflammation
researchProduct

Prenatal diagnosis of a rhodopsin mutation using chemical cleavage of the mismatch

2002

Objective: Mutations of the rhodopsin gene are responsible for autosomal dominant or recessive retinitis pigmentosa (RP). The present study reports the first prenatal diagnosis performed on chorionic villi biopsy of a pregnant woman affected by a severe form of autosomal dominant transmitted RP, due to the Arg135Trp substitution. Methods: The rhodopsin gene was analysed by automated direct sequencing and, for the first time, by fluorescence-assisted mismatch analysis (FAMA). The latter is an inexpensive, rapid and particularly sensitive method, based on the chemical cleavage of the mismatch in heteroduplex DNA molecules marked with strand-specific fluorophores. Results: FAMA is a feasible p…

AdultRhodopsinrhodopsin geneBase Pair MismatchSettore MED/30 - Malattie Apparato VisivoDNA Mutational Analysisfama; retinitis pigmentosa; rhodopsin geneDNAHeteroduplex AnalysisPolymerase Chain ReactionSettore BIO/18 - GeneticaChorionic Villi SamplingPregnancyretinitis pigmentosaMutationHumansFemalefama
researchProduct

PCOS: metabolic impact and long-term management.

2012

Polycystic ovary syndrome (PCOS) is the most frequent endocrinopathy in women, affecting up to 10% of those in reproductive age. Furthermore, PCOS presents a lifetime risk of type II diabetes, cardiovascular diseases and endometrial cancer. Women with PCOS have increased cardiovascular risk; however, the risk is not the same in all patients and it is necessary to assess an individual risk profile. There is a discrepancy between increased cardiovascular risk at young age and postmenopausal number of cardiovascular events, probablu depending on changes in androgen ovarian function after the forties. However, changes with age of metabolic profile in women with PCOS have not been studied yet an…

AdultSettore MED/09 - Medicina InternaAdolescentComorbiditySettore MED/11 - Malattie Dell'Apparato CardiovascolareMetforminSettore MED/13 - EndocrinologiaDiabetes Mellitus Type 2Cardiovascular DiseasesRisk FactorsObesity AbdominalPCOS Metabolic Syndrome Cardiovascular risk aging insulin resistance hyperandrogenismHypertensionHumansFemaleHydroxymethylglutaryl-CoA Reductase InhibitorsInsulin ResistanceChildAntihypertensive AgentsDyslipidemiasPolycystic Ovary SyndromeMinerva ginecologica
researchProduct

How can droplet formation occur in endodontically treated teeth during bonding procedures?

2008

PURPOSE: The aim of this in vivo study was to clarify how blistering formation occurs along intraradicular dentin bonded interfaces. MATERIALS AND METHODS: Patients were selected and post space was prepared in vivo in endodontically treated teeth. Post space was etched, dried with ethanol, and bonded with one of the following adhesive systems: All Bond 2, XP-Bond, Clearfil SE Bond, Xeno III. The four adhesives were considered as representative of each bonding system class. An additional group was prepared with phosphoric acid treatment + application of Pre-Bond unfilled resin of All Bond 2, without the use of the primer agent. Etching was avoided for self-etching materials. Replicas of the …

AdultTooth NonvitalEthanolSurface PropertiesDental BondingMiddle Agedadhesive permeability simplified adhesive root canal droplet formationResin CementsAcid Etching DentalSettore MED/28 - Malattie OdontostomatologicheDentin-Bonding AgentsDentinMicroscopy Electron ScanningSolventsHumansMethacrylatesReplica TechniquesPhosphoric AcidsDental Pulp CavityAgedPost and Core Technique
researchProduct

Retinal myelinated nerve fibers associated with macular pseudohole

2008

We report the case of a 24-year-old woman who presented unilateral extensive peripapillary myelinated nerve fibers associated with macular pseudohole and bilateral low myopia. Visual acuity, slit lamp biomicroscopy, automated perimetry, fundus color photography, and optical coherence tomography (Stratus® OCT) were performed. We discuss the clinical findings and diagnostic details of unilateral extensive peripapillary myelinated nerve fibers associated with macular pseudohole.

AdultVisual acuitygenetic structuresMyelinated nerve fiberNerve fiberEpiretinal membrane Macular pseudohole Oligodendrocytes Retinal myelinated nerve fibersFundus (eye)Nerve Fibers MyelinatedRetinal DiseasesmedicineHumansMacula LuteaFluorescein AngiographyMacular holebusiness.industrySettore MED/30 - Malattie Apparato VisivoOptic NerveAnatomymedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structureOptic nerveMaculopathyFemalesense organsEpiretinal membranemedicine.symptombusiness
researchProduct

Possible link between Hashimoto's thyroiditis and oral lichen planus: a novel association found

2013

Objectives: Hashimoto's thyroiditis as well as lichen planus has been associated to a number of disorders, generally of auto-immune origin. A novel possible association between oral lichen planus (OLP) and Hashimoto's thyroiditis (HT) is here proposed on the basis of a cross-sectional survey. Materials and methods: One hundred and five unrelated OLP patients were considered. Diagnosis of HT was based on positive serum anti-TPO, anti-Tg, TSH levels and the typical ultrasound pattern of the thyroid gland. Results: In the present survey, the prevalence of HT in the OLP group was 14. 3 % whereas the prevalence of HT-related hypothyroidism in the general population was reported to be equal to 1 …

Adultendocrine systemmedicine.medical_specialtyendocrine system diseasesPopulationThyrotropinAutoimmunityHashimoto Diseasemedicine.disease_causeAutoantigensIodide PeroxidaseGastroenterologyAsymptomaticThyroiditisAutoimmunityHashimoto's thyroiditistomatognathic systemSettore MED/28 - Malattie OdontostomatologicheIron-Binding ProteinsInternal medicinePrevalencemedicineHumansThyroid NoduleOral mucosaeducationGeneral DentistryAutoantibodieseducation.field_of_studybusiness.industryThyroidMiddle AgedCirculating thyroid antibodiesmedicine.diseaseAnti-thyroid autoantibodiesThyroxinestomatognathic diseasesCross-Sectional Studiesmedicine.anatomical_structureItalyOral lichen planuHashimoto's thyroiditis; Oral lichen planus; Autoimmunity; Circulating thyroid antibodiesTriiodothyronineFemaleOral lichen planusmedicine.symptombusinessLichen Planus OralClinical Oral Investigations
researchProduct

Changes in colour discrimination during the menstrual cycle.

2006

A group of normal women of reproductive age were recruited to investigate colour discrimination during the various phases of the menstrual cycle. Colour vision was tested with the Farnsworth-Munsell 100-hue arrangement test, and the test was administered at 3 time points: the beginning of the cycle, ovulation, and the end of the cycle. We found that colour discrimination was better at ovulation than at the other 2 time points. It is possible that psychological as well as hormonal factors could contribute to improved colour vision performance at ovulation.

Adultgenetic structuresColor visionmedia_common.quotation_subjectVisual AcuityPhysiologyReproductive ageSettore BIO/10 - BiochimicamedicineHumansColor perception testOvulationMenstrual cycleMenstrual Cyclemedia_commonColor Perception Testsmedicine.diagnostic_testSettore MED/30 - Malattie Apparato Visivobusiness.industryColour VisionGeneral Medicineeye diseasesSensory SystemsMestrual CycleOphthalmologybusinessFarnsworth-Munsell 100 hue testColor PerceptionOphthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
researchProduct

Results of closed subtalar dislocations.

2015

Background The subtalar dislocation (SD) of the foot is an uncommon injury characterized by a simultaneous dislocation of talocalcaneal and talonavicular joints without involvement of the tibiotalar and calcaneocuboid joints. Purposes The purpose of this study was to evaluate the clinical and radiological outcome in a consecutive series of close SD. Methods We retrospectively evaluated a case series of patients who presented a close SD. Thirteen patients were selected for this study. There were 9 patients with a medial SD, 3 patients with a lateral dislocation and 1 patient with a posterior subtalar dislocation. Results The most frequent symptoms observed in our study included transient mil…

Adultmedicine.medical_specialtyAdolescentRadiographyJoint Dislocations03 medical and health sciencesYoung Adult0302 clinical medicineFoot traumaPeritalar dislocationSettore MED/33 - Malattie Apparato LocomotoremedicineHumansOrthopedics and Sports MedicineJoint dislocationAnkle dislocationFoot InjuriesAgedRetrospective StudiesAged 80 and over030222 orthopedicsbusiness.industryRetrospective cohort study030229 sport sciencesMiddle Agedmedicine.diseaseSubtalar dislocationSurgeryRadiographymedicine.anatomical_structureRadiological weaponOrthopedic surgerySurgeryFoot InjuryAnkleDislocationbusinessMusculoskeletal surgery
researchProduct

Comparison of the rates of joint arthroplasty in patients with severe factor VIII and IX deficiency: an index of different clinical severity of the 2…

2009

AbstractData from the Italian Hemophilia Centres were collected to perform a retrospective survey of joint arthroplasty in patients with severe hemophilia. Twenty-nine of 49 hemophilia centers reported that 328 of the 347 operations were carried out in 253 patients with severe hemophilia A (HA) and 19 in 15 patients with severe hemophilia B (HB). When results were normalized to the whole Italian hemophilia population (1770 severe HA and 319 severe HB), patients with HA had a 3-fold higher risk of undergoing joint arthroplasty (odds ratio [OR], 3.38; 95% confidence interval [CI], 1.97-5.77; P < .001). These results were confirmed after adjustment for age, HIV, hepatitis C virus (HCV), and…

Adultmedicine.medical_specialtyAdolescentmedicine.medical_treatmentImmunologyPopulationmacromolecular substancesGene mutationHemophilia AHemophilia BSeverity of Illness IndexBiochemistryArthroplastySettore MED/15 - Malattie Del SangueCohort StudiesYoung AdultRisk Factorshemic and lymphatic diseasesInternal medicineSeverity of illnessmedicineCoagulopathyHumansChildeducationRetrospective Studieseducation.field_of_studyHematologyhamophilia arthroplastybusiness.industryRetrospective cohort studyCell BiologyHematologyOdds ratioBlood Coagulation DisordersMiddle Agedmedicine.diseaseArthroplastySurgeryItalyJoint DiseasesbusinessAlgorithms
researchProduct

Unexpected high frequency of genital involvement in women with clinical and hostological features of oral lichen planus

2006

The main aims of this cross-sectional study were: (i) to assess the frequency of genital (vulval) lichen planus (VLP) and vulval lichen sclerosus (VLS) in women affected with oral lichen planus (OLP), regardless of the genital symptoms reported; and (ii) to verify whether any demographic, clinical, or histological features of OLP are associated with a higher risk of vulvo-vaginal involvement. Fifty-five women, presenting OLP, consecutively underwent gynaecological examination and, if they demonstrated positive clinical signs of VLP, underwent biopsy. After a drop-out of 14 subjects, 31/41 (75.6%) were found to have signs of genital involvement, of which 13/31 (44.0%) were asymptomatic. Foll…

Adultmedicine.medical_specialtyDermatologyLichen sclerosusSettore MED/08 - Anatomia PatologicaAsymptomaticVulvar Lichen Sclerosusoral lichen planuTherapeutic approachstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheBiopsyoral lichen planus; genital lichen planusgenital lichen planusMedicineHumansSex organAgedAged 80 and overmedicine.diagnostic_testbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseDermatologySettore MED/40 - Ginecologia E Ostetriciastomatognathic diseasesGynaecological examinationCross-Sectional StudiesOral lichen planusFemaleVulvar DiseasesMultivariate statisticalmedicine.symptombusinessLichen Planus Oral
researchProduct