Search results for "man studie"

Frings, Theodor (1886–1968)

2006

Theodor Frings, late professor of German language and literature at the university of Leipzig, dealt with the dynamics of language in history, with the contact of German with neighbouring languages, such as, Dutch, Romance (“Germania Romana”) and Slavic languages. To Frings, the explanation of language change was the ‘external’ history. His description of the regional basis of Standard German, namely, the compromise language caused by dialect mixture in east Germany, was well accepted.

2004

In the elderly, many alterations of both innate and clonotypic immunity have been described. Alterations to the immune system in the elderly are generally viewed as a deterioration of immunity, leading to the use of the term immunosenescence. However, although many immunological parameters are often notably reduced in the elderly, retained function of both innate and clonotypic immunity in the elderly is tightly correlated to health status. Recognising the important role of the immune system in ageing, over the last few years, journals oriented towards gerontology and geriatric sciences have increasingly published articles dealing with the immunology of ageing, but a specialised journal in …

Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors

2020

Murine models of cytomegalovirus (CMV) infection have revealed an exceptional kinetics of the immune response. After resolution of productive infection, transient contraction of the viral epitope-specific CD8 T-cell pool was found to be followed by a pool expansion specific for certain viral epitopes during non-productive &lsquo

Strategische Zitate. Zu Friedrich Kittlers Heidegger-Lektüre

2014

The article examines the variant ways in which Friedrich Kittler quotes certain passages of Martin Heiddegger’s texts and especially of Heidegger’s seminal book Sein und Zeit (1927) over the course of his academic career. It argues that the telos of Kittler’s variant, non-philological quotation is the legitimation of German studies as well as cultural studies by telling a myth: Martin Heidegger, a philosophical authority, has consequently affirmed media technology. Thus, Kittler’s practice of citation reveals its strategic intention. A reading of literary texts that takes into account the apriori function of technological innovation is an appropriate method supported by Geistesgeschichte.

Impact of crestal and subcrestal implant placement upon changes in marginal peri-implant bone level. A systematic review.

2019

Background To systematically assess studies analyzing peri-implant bone loss in implants placed in crestal and subcrestal position. Material and Methods Following the recommended methods for systematic reviews and meta-analyses (PRISMA), an electronic search was conducted in the PubMed (MEDLINE), EMBASE and LILACS databases to identify all relevant articles published up until April 2017. The search included human studies comparing marginal bone loss (MBL) between a control group and a study group with a minimum of 10 patients and a minimum follow-up of 6 months after prosthetic loading with rough neck implants. Two independent reviewers assessed the risk of bias in the selected studies base…

Non-uniform displacement and strain between the soleus and gastrocnemius subtendons of rat Achilles tendon

2018

Achilles tendon (AT) comprises of 3 subtendons arising from the soleus (SOL) and the lateral (LG) and medial (MG) heads of the gastrocnemius muscle. While recent human studies show differential displacement within AT, these displacements have not been attributed to specific subtendons. We tested the hypothesis that the SOL and LG subtendons show differential displacement and strain during various combinations of SOL, LG, and MG excitations. Movement of knots, sutured onto SOL and LG subtendons of 12 Wistar rats, was videotaped, while the muscles were stimulated intramuscularly and ankle torque was assessed. When SOL only was stimulated, the plantar flexion torque was the smallest among the …

The associations of serum serotonin with bone traits are age- and gender-specific

2014

Context Serotonin plays a potential role in bone metabolism, but the nature and extent of this relationship is unclear and human studies directly addressing the skeletal effect of circulating serotonin are rare. Objective The study aimed to investigate the associations between serum serotonin and bone traits at multiple skeletal sites in women and men. Subjects and Methods Subjects were part of the CALEX-family study and comprised 235 young women, 121 premenopausal women, 124 postmenopausal women, and 168 men. Body composition was assessed using DXA, as was areal bone mineral density (aBMD) of spine, femur and whole body. In addition, pQCT was used to determine bone properties at tibial mid…

Prenatal perfluoroalkyl substance exposure and neuropsychological development throughout childhood: The INMA Project.

2021

Abstract Background Perfluoroalkyl substances (PFASs) have been related to neurodevelopmental toxicity in animals. However, human studies are inconclusive. Objectives To evaluate the association between prenatal PFAS exposure and neuropsychological development during childhood. Methods 1240 mother–child pairs from the Spanish INMA Project were analyzed. Perfluorohexanesulfonic acid (PFHxS), perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), and perfluorononanoic acid (PFNA) were measured in first-trimester maternal plasma. Neuropsychological development was assessed at 14 months, 4–5 and 7 years covering four domains: general cognitive, general motor, attention, and working me…

Certification of a 41Ca dose material for use in human studies (IRMM-3703) and a corresponding set of isotope reference materials for 41Ca measuremen…

2005

Abstract The long-living radioisotope 41Ca could overcome current limitations in assessing the impact of interventions on bone health in controlled human studies. Changes in bone Ca metabolism can be identified directly via the induced changes in 41Ca excretion from 41Ca-labelled bones via the n(41Ca)/n(40Ca) ratio in urine. A 41Ca dose material (IRMM-3703), for use in human studies, was produced by IRMM within the EC funded project OSTEODIET. The 41Ca base material was purified and the purified solution is certified for both isotopic composition and amount content by isotope dilution mass spectrometry. The 44Ca-enriched isotope reference material, IM-6009, was used as spike and the natural…

Peri-implantitis : associated microbiota and treatment

2010

Introduction: Peri-implantitis is a late complication of dental implant treatment, induced by microbiological changes. Since the disorder is frequent, a review is indicated of the microorganisms that influence it and of the existing treatment options. Objective: To conduct a literature review of the microbiota associated to peri-implantitis and the existing treatment options. Material and Method: A PubMed literature search was made of the studies on the microbiota associated to dental implants in healthy patients and patients with peri-implantitis, as well as of the latest treatment developments, using the following key words: "peri-implantitis AND microbiota", "periimplantitis AND microbio…