Search results for "mantle"
showing 10 items of 322 documents
First volatile inventory for Gorely volcano, Kamchatka
2012
We report here the very first assessment of volatile flux emissions from Gorely, an actively degassing volcano in Kamchatka. Using a variety of in situ and remote sensing techniques, we determined the bulk plume concentrations of major volatiles (H2O 93.5%, CO2, 2.6%, SO2 2.2%, HCl 1.1%, HF 0.3%, H2 0.2%) and trace-halogens (Br, I), therefore estimating a total gas release of 11,000 tons·day−1 during September 2011, at which time the target was non-eruptively degassing at 900°C. Gorely is a typical arc emitter, contributing 0.3% and 1.6% of the total global fluxes from arc volcanism for CO2 and HCl, respectively. We show that Gorely's volcanic gas (H2O/SO2 43, CO2/SO2 1.2, HCl/SO2 0.5) is a…
Coupled petrological-geodynamical modeling of a compositionally heterogeneous mantle plume
2018
Abstract Self-consistent geodynamic modeling that includes melting is challenging as the chemistry of the source rocks continuously changes as a result of melt extraction. Here, we describe a new method to study the interaction between physical and chemical processes in an uprising heterogeneous mantle plume by combining a geodynamic code with a thermodynamic modeling approach for magma generation and evolution. We pre-computed hundreds of phase diagrams, each of them for a different chemical system. After melt is extracted, the phase diagram with the closest bulk rock chemistry to the depleted source rock is updated locally. The petrological evolution of rocks is tracked via evolving chemi…
Relapsed and/or Refractory Mantle Cell Lymphoma: What Role for Temsirolimus?
2012
Mantle Cell Lymphoma (MCL) is associated with a dismal prognosis. Recently, along with the improved understanding of the pathophysiology of this disease, new first line regimens have been established and in addition novel treatment options have entered the clinical arena. In consequence, prognosis of the disease has fortunately improved. We here focus on the rationale, current clinical knowledge and future concepts of Temsirolimus, an inhibitor of mTOR, in the treatment of MCL. At this time this drug has been shown to be effective as single agent for relapsed disease and early combination data show promising results. In addition, with a brief outline of other treatment options, we aim to g…
Active Degassing of Deeply Sourced Fluids in Central Europe: New Evidences From a Geochemical Study in Serbia
2021
We report on the results of an extensive geochemical survey of fluids released in the Vardar zone (central-western Serbia), a mega-suture zone at the boundary between Eurasia and Africa plates. Thirty-one bubbling gas samples are investigated for their chemical and isotopic compositions (He, C, Ar) and cluster into three distinct groups (CO2-dominated, N2-dominated, and CH4-dominated) based on the dominant gas species. The measured He isotope ratios range from 0.08 to 1.19 Ra (where Ra is the atmospheric ratio), and reveal for the first time the presence of a minor (<20%) but detectable regional mantle-derived component in Serbia. δ13C values range from −20.2‰ to −0.1‰ (versus PDB), with…
Trace-element partitioning between amphibole and silicate melt.
2007
Knowledge of the partitioning behavior of trace elements between solid and liquid is a prerequisite for modern igneous and mantle petrology. Most of the mathematical models simulating melt generation, migration and evolution within the mantle and/or the crust require the availability of reliable solid/liquid partition coefficients for the mineral phases involved in the process. Calcic amphiboles are extremely important for the understanding of lithospheric processes because of both their common occurrence in a variety of igneous and metamorphic rocks types and their capability of hosting a large number of geochemically important trace elements. A series of studies on the partitioning behavi…
Heterogeneity of volatile sources along the Halmahera arc, Indonesia
2021
co-auteur étranger; International audience; The parallel Halmahera and Sangihe arcs in eastern Indonesia are sites of active arc-arc collision of considerable interest in developing understanding of the geodynamics and geochemistry of subduction zones. Owing to the comparative remoteness of the region, few ground-based studies of the volcanoes have been undertaken. Here, we report and integrate gas measurements and (isotope) geochemical analyses of lava samples for Dukono, Ibu, Gamkonora, Gamalama, and Makian volcanoes of the Halmahera arc. Summing gas fluxes for all five volcanoes indicates arcscale emission budgets for H 2 O, CO 2 , SO 2 , H 2 S, and H 2 of 96300±27000, 2093±450, 944±400,…
Results of a Phase II Study of Pixantrone in Combination with Cyclophosphamide, Vincristine, and Prednisone in Patients with Relapsed Aggressive Non-…
2006
Abstract Background: Pixantrone is a novel aza-anthracenedione with less cardiotoxicity and superior activity compared to doxorubicin and mitoxantrone in murine leukemia and lymphoma tumor models. Pixantrone as single agent therapy led to major responses in patients (pts) with multiply relapsed aggressive non-Hodgkin’s lymphoma (NHL), including diffuse large B-cell lymphoma (DLCL). In a phase I dose-ranging study of pixantrone (80 to 180 mg/m2) replacing doxorubicin (CPOP) in a CHOP-like regimen, the optimal dose (RD) from that study was found to be 150 mg/m2. Methods: In this international, multi-center, phase II study the primary objective was to assess the efficacy and safety of the CPOP…
Geochemical characteristics of Cretaceous carbonatites from Angola
1999
Abstract The Early Cretaceous (138–130 Ma) carbonatites and associated alkaline rocks of Angola belong to the Parana-Angola-Etendeka Province and occur as ring complexes and other central-type intrusions along northeast trending tectonic lineaments, parallel to the trend of coeval Namibian alkaline complexes. Most of the Angolan carbonatite-alkaline bodies are located along the apical part of the Mocamedes Arch, a structure representing the African counterpart of the Ponta Grossa Arch in southern Brazil, where several alkaline-carbonatite complexes were also emplaced in the Early Cretaceous. Geochemical and isotopic (C, 0, Sr and Nd) characteristics determined for five carbonatitic occurren…
Chemo-probe into the mantle origin of the NW Anatolia Eocene to Miocene volcanic rocks: Implications for the role of, crustal accretion, subduction, …
2017
Post-collisional Cenozoic magmatic activity in NW Anatolia produced widespread volcanism across the region. In the Biga Peninsula, in the west, medium-K calc-alkaline to ultra-K rocks with orogenic geochemical signature were emplaced at similar to 43-15 Ma (Biga orogenic volcanic rocks; BOVR). Volcanic activity in the Central Sakarya region, to the east, is mainly restricted to-53-38 Ma, but also continued during the Early Miocene with small basaltic extrusives (Sakarya orogenic volcanic rocks; SOVR). This study presents a new set of geochemical data (whole rock major and trace elements and Sr-Nd-Pb isotopic compositions), obtained from the Cenozoic calc-alkaline volcanic rocks from these t…
Does second phase content control the evolution of olivine CPO type and deformation mechanisms? A case study of paired harzburgite and dunite bands i…
2021
Abstract We have examined the microstructures and crystallographic preferred orientations (CPOs) of six “paired” harzburgite and dunite samples from a small (~ 1 km2) area in the Ellis Stream Complex, Red Hills Massif, Dun Mountain ophiolite belt in New Zealand. Here, banded peridotites with isoclinal folds, E-W striking vertical foliations and vertical lineations are inferred to result from shear on vertical planes that overprint previous mantle structures. The samples contain five different olivine CPOs: typically known as A, C, D, E and AG-types. The co-located harzburgite and dunite of each pair show different CPOs (e.g., A vs E type). In each pair, dunite generally has larger grain siz…