Search results for "mapping"
showing 10 items of 1508 documents
The ‘recent’ forests of Mount Venda (Padua, Italy): when historical cartography and archaeobotany tell quite a different story
2018
Forests, like agricultural systems and housing, are an integral part of the human landscapes. They evolve over time, not only in response to environmental factors (e.g. climate change) but also in response to developments in human society. This work on the analysis of forest dynamics in Euganean hills is the result of research carried out as part of the research programmes THISTLE (MSCA Fellowship, grant agreement: 656397) and MEMOLA (EU FP7 Project , grant agreement: 613265). The work is focused on two mountains in particular: Monte Venda and Monte della Madonna. The archaeobotanical investigations reveal the presence of ancient forests (since the 14th century) in these areas , although th…
Generation of monoclonal antibodies against human regulatory T cells.
2009
Abstract Natural CD4 + CD25 + Foxp3 + regulatory T cells (Tregs) control the activation of the immune system and therefore have become a major area of research in immunology. The generation of monoclonal antibodies against human Tregs offers the possibility to discover novel Treg-specific or Treg-associated surface markers and to identify targets for a therapeutic modulation of Tregs. Here we present a methodology optimized to efficiently induce and select mAb against human Tregs by repeated immunization of mice with Tregs from a single donor and a differential two-step flow cytometry-based hybridoma screening procedure.
The Fumarate/Succinate Antiporter DcuB of Escherichia coli Is a Bifunctional Protein with Sites for Regulation of DcuS-dependent Gene Expression
2008
DcuB of Escherichia coli catalyzes C4-dicarboxylate/succinate antiport during growth by fumarate respiration. The expression of genes of fumarate respiration, including the genes for DcuB (dcuB) and fumarate reductase (frdABCD) is transcriptionally activated by C4-dicarboxylates via the DcuS-DcuR two-component system, comprising the sensor kinase DcuS, which contains a periplasmic sensing domain for C4-dicarboxylates. Deletion or inactivation of dcuB caused constitutive expression of DcuS-regulated genes in the absence of C4-dicarboxylates. The effect was specific for DcuB and not observed after inactivation of the homologous DcuA or the more distantly related DcuC transporter. Random and s…
Best approximation and variational inequality problems involving a simulation function
2016
We prove the existence of a g-best proximity point for a pair of mappings, by using suitable hypotheses on a metric space. Moreover, we establish some convergence results for a variational inequality problem, by using the variational characterization of metric projections in a real Hilbert space. Our results are applicable to classical problems of optimization theory.
Mappings of finite distortion : size of the branch set
2018
Abstract We study the branch set of a mapping between subsets of ℝ n {\mathbb{R}^{n}} , i.e., the set where a given mapping is not defining a local homeomorphism. We construct several sharp examples showing that the branch set or its image can have positive measure.
The Nitsche phenomenon for weighted Dirichlet energy
2018
Abstract The present paper arose from recent studies of energy-minimal deformations of planar domains. We are concerned with the Dirichlet energy. In general the minimal mappings need not be homeomorphisms. In fact, a part of the domain near its boundary may collapse into the boundary of the target domain. In mathematical models of nonlinear elasticity this is interpreted as interpenetration of matter. We call such occurrence the Nitsche phenomenon, after Nitsche’s remarkable conjecture (now a theorem) about existence of harmonic homeomorphisms between annuli. Indeed the round annuli proved to be perfect choices to grasp the nuances of the problem. Several papers are devoted to a study of d…
Exploring automatic grouping procedures in ceramic petrology
2004
Although a small number of studies have attempted to introduce automatic grouping procedures into thin section petrography of archaeological ceramics, the majority of studies continue to be carried out by non-automatic means. Although such an approach with the single observer grouping samples has a number of advantages, it is problematic when dealing with large numbers of samples. This paper aims to explore different coding systems and statistical analyses for grouping ceramic thin sections. In the example discussed a number of variables are defined, codified and analysed by correspondence analysis, classical multidimensional scaling, non-metric isotonic multidimensional scaling and Sammon …
Mapping child maltreatment risk: a 12-year spatio-temporal analysis of neighborhood influences.
2017
Abstract Background ‘Place’ matters in understanding prevalence variations and inequalities in child maltreatment risk. However, most studies examining ecological variations in child maltreatment risk fail to take into account the implications of the spatial and temporal dimensions of neighborhoods. In this study, we conduct a high-resolution small-area study to analyze the influence of neighborhood characteristics on the spatio-temporal epidemiology of child maltreatment risk. Methods We conducted a 12-year (2004–2015) small-area Bayesian spatio-temporal epidemiological study with all families with child maltreatment protection measures in the city of Valencia, Spain. As neighborhood units…
Enhancer trap infidelity in Drosophila optomotor-blind
2013
Reporter gene activity in enhancer trap lines is often implicitly assumed to mirror quite faithfully the endogenous expression of the "trapped" gene, even though there are numerous examples of enhancer trap infidelity. optomotor-blind (omb) is a 160 kb gene in which 16 independent P-element enhancer trap insertions of three different types have been mapped in a range of more than 60 kb. We have determined the expression pattern of these elements in wing, eye-antennal and leg imaginal discs as well as in the pupal tergites. We noted that one pGawB insertion (omb (P4) ) selectively failed to report parts of the omb pattern even though the missing pattern elements were apparent in all other 15…
Methodological advances in brain connectivity
2012
Determining how distinct neurons or brain regions are connected and communicate with each other is a crucial point in neuroscience, as it allows to investigate how the functional integration of specialized neural populations enables the emergence of coherent cognitive and behavioral states. The general concept of brain connectivity encompasses different aspects: structural connectivity is related to the description of anatomical pathways and synaptic connections; functional connectivity investigates statistical dependencies between spatially separated brain regions; effective connectivity refers to models aimed at elucidating driver-response relationships. The study of these different modes…