Search results for "marqueurs"
showing 10 items of 22 documents
Research of prognostic biomarkers in Tunisian patients with bladder cancer
2016
Bladder cancer is the first most common urogenital cancer in men in Tunisia, with a high recurrence rate. Patients with muscle-invasive disease develop metastasis. The need for expensive continuous surveillance. In this thesis we try to search some candidate biomarkers. Their use for cancer staging and personalization of therapy at the time of diagnosis in order to identify a better treatment could improve patient care. The aim of this first part of our study was to investigate the clinical significance of three immune cell-related transcription factors, T-bet, GATA-3 and Bcl-6 in Tunisian patients with bladder cancer. We found that T-bet level was significantly higher in invasive carcinoma…
Identification of stress factors in intensive care units: Is a specific stress scale necessary?
2019
International audience; Background: Intensive care units (ICUs) are a health environment particularly affected by suffering at work. These units treat patients with serious medical conditions with an immediate life-threatening risk in an emergency situation. As a result, caregivers are confronted intensively and repeatedly with an extreme clinic. Currently, many tools used to assess caregiver stress are not as close as possible to the professional experience and do not take into account the subjective perception of stressors. The objective of this qualitative study is to rely directly on the way professionals perceive their work, and to identify the specificity of stress factors in ICU. Met…
Diversité génétique et aromatique de la truffe de Bourgogne
2013
Truffles are ectomycorrhizal Ascomycota fungi belonging to the Tuberaceae family and more specifically to the Tuber genus. More than thirty Tuber species are currently described in Europe. In this thesis, we specifically focused on the Tuber aestivum-uncinatum model. This truffle is commonly called "Burgundy Truffle" and has a gastronomic and cultural interest.The first part of this thesis focused on the taxonomic status of the Burgundy truffle (Tuber uncinatum). For this, we used a multi-marker approach combining several genetic markers commonly used at the interspecific scale. Our analyses showed that the two taxa, Tuber aestivum (summer truffle) and Tuber uncinatum are conspecific.In the…
Projet SALAMANDER : Biomarqueurs salivaires du régime méditerranéen associés à une protection au long terme contre le diabète de type 2
2017
Discrimination génétique de clones de Pinot Noir et de Chardonnay par marquage microsatellite
2013
National audience; Face aux difficultés d’améliorer la traçabilité des clones, nous avons exploré la possibilité d’utiliser des marqueurs neutres tels que les marqueurs microsatellites pour discriminer des clones de vigne. Les marqueurs microsatellites ont été choisis pour leurs caractères mono-locus, co-dominants et faciles à développer. Il sont ainsi permis de caractériser une collection de clones Pinot Noir et de Chardonnay. Cette collection de 82 clones est composée d’un clone de Gamay constituant la référence extérieure définissant l’enracinement de l’arbre phylogénétique, 48 clones de Pinot Noir et 33 clones de Chardonnay. Cette collection est constituée de clones agrées, de clones is…
Terres et pierres pour matières de cultures : l'apparition et la diffusion de nouveaux modes et matériaux de construction dans le Nord-Est de la Gaul…
2017
Roman building materials often arose a growing interest through their presence in early contexts, sometimes way before Gallic Wars. Made from natural resources, their final shape corresponds to anthropogenic and cultural constraints. However, even if building materials are not neglected during archaeological excavations, so far they have been considered as playing a minor part in understanding ancient sites. Economical, technical and architectural aspects are regularly mentioned, creating the picture of an exploited « landscape » around the studied areas, but the question of materials as cultural markers witnessing intercultural relations between Rome and Gallic tribes has never really been…
A conversational, morpho-syntactic and intonation analysis of discourse markers in political discourse : A case study of presidential debates and tel…
2020
This thesis proposes a morphosyntactic, prosodic and conversational analysis of discourse markers in presidential debates and televised political talkshows in the United States of America. The main object of the study is the role of discourse markers in the sequential structuring and in the enunciative organisation of presidential debates in the United States of America. Discourse markers, in correlation with gestures and intonation, contribute significantly to the construction of the verbal exchange between the various participants in mediated political discourse. To achieve its goals, this thesis draws on several theoretical frameworks dealing with spontaneous speech (Benveniste and Berre…
Development of a scale of perceived stressors specific to ICU: the PS-ICU scale
2019
International audience
Les marqueurs du discours et la notion de « connivence » : les cas de « enfin », « car, « en fin » et « pues » ».
2018
International audience
Pathologies et traumatismes professionnels au Néolithique ; des mineurs de silex à Chouilly « la Grifaine » (Marne) ?
2021
La fouille réalisée en 2016 par le service archéologique de Reims Métropole sur le site de Chouilly « La Grifaine » a été l’occasion de compléter nos connaissances sur les hypogées de la Marne. L’examen détaillé de l’état sanitaire des sujets issus de l’hypogée F10 a mis en exergue la récurrence de différents traumatismes et de lésions dégénératives qui plaident en faveur d’une activité spécifique qui pourrait être en lien avec l’extraction du silex. Les indices ostéologiques concernent essentiellement les individus inhumés dans les niveaux les plus récents et témoignent, soit d’une modification du recrutement des individus inhumés, soit d’une évolution des activités au cours du temps. The …