Search results for "maternal"

Prenatal androgen exposure modulates cellular and humoral immune function of black-headed gull chicks

2005

Avian eggs contain considerable amounts of maternal yolk androgens, which have been shown to beneficially influence the physiology and behaviour of the chick. As androgens may suppress immune functions, they may also entail costs for the chick. This is particularly relevant for colonial species, such as the black-headed gull (Larus ridibundus), in which the aggregation of large numbers of birds during the breeding season enhances the risk of infectious diseases for the hatching chick.To test the effect of maternal yolk androgens on the chick's immune function, we experimentally manipulated, in a field study, yolk androgen levels within the physiological range by in ovo injection of either a…

Food supplementation reveals constraints and adaptability of egg quality in the magpie Pica pica

2015

Differences in the deposition of limited maternal resources to eggs can reflect the optimal allocation to manipulate offspring phenotype, or constraints caused by maternal condition. We examined multiple maternal substances transferred to eggs in the magpie Pica pica to test the hypothesis that certain substances represent constraint and some optimal allocation. We did this by supplementary feeding magpies prior to egg-laying and then comparing the effect of food on maternal substances in conjunction with laying order relative to a control group. Certain substances such as carotenoids, immunoglobulins and avidin responded positively to food supplementation, whereas others, such as testoste…

Sex-ratio of Skylark Alauda arvensis broods in relation to timing of breeding.

2006

4 pages; International audience; Capsule Earlier broods tend to be more male biased than later broods.

Dietary exposure in utero and during lactation to a mixture of genistein and an anti-androgen fungicide in a rat mammary carcinogenesis model

2015

Endocrine disruptors may play substantial roles in the high incidence of breast cancer. We previously described how early exposure to the mixture of phytoestrogen genistein (G) and the anti-androgen vinclozolin (V) affects peripubertal mammary development. This study evaluates the carcinogenic potential of exposure to V alone or associated with G from conception until weaning in Wistar rats. Dams were exposed to V, G or GV during pregnancy/lactation. At PND50 offspring were treated with DMBA[7,12-dimethylbenz(a)anthracene]. V or GV maternal exposure decreased number of DMBA-induced mammary tumors in the offspring, without significant modifications in tumor incidence, multiplicity and latenc…

Sex-specific transgenerational effects of early developmental conditions in a passerine.

2007

Most studies dealing with the trade-off between offspring number and quality have overlooked the long-term consequences for the progeny. High investment in offspring number usually results in an increased competition among nest mates. The deterioration of the early developmental conditions, due to this increased competition, can impair individual quality over the long term, and subsequently affect survival and lifetime fecundity. Moreover, the consequences of the allocation rule to offspring number vs. quality can extend across generations and give raise to grandparental effects. These transgenerational trade-offs have been explored rarely. In the present study, we manipulated the breeding …

Consequences of a high sugar/high fat maternal diet on protein expression in young rat salivary glands

2015

Introduction: Early nutrition through maternal diet during pregnancy and breastfeeding was shown to have an impact on obesity in childhood. Experiments on animal models have also indicated alterations regarding taste preferences. In addition, salivary physiology has a documented role in taste preferences and food intake in rodents. The objective of this study was therefore to study the impact of maternal diet on salivary glands’ protein profiles of the offspring.Materials and methods: Female rats received during gestation and lactation either a control (C) or a high fat / high sugar diet (WD for “Western Diet”). 18 offspring rats (9C/9WD) were sacrificed at 25 days of age, i.e. shortly afte…

Are maternal practices associated with children’s eating difficulties?

2013

Détermination et transmission du goût. Importance des expériences précoces

2013

Compte tenu que les préférences et habitudes alimentaires sont acquises très précocement il est important de mieux comprendre l’impact des expériences précoces sur l’acceptation des fruits et légumes lors de la diversification alimentaire et pendant les premières années de vie. Au cours de cette présentation, des résultats d’études expérimentales ou observationnelles portant sur l’impact de l’allaitement, des pratiques de diversification (variété de l’offre, exposition répétée) et des pratiques éducatives sur l’acceptation des fruits et légumes seront présentées. La transmission des préférences alimentaires peut commencer au cours de la vie intra-utérine. Il a été montré que des nouveau-nés…

Impact of a maternal high fat high sucrose diet on progeny's olfactory system

2018

International audience

Abnormal peripubertal development of the rat mammary gland following exposure in utero and during lactation to a mixture of genistein and the food co…

2011

The impact of early exposure to endocrine disruptor mixtures on mammary gland development is poorly known. Here, we identify the effects of a conception to weaning exposure of rats to the phytoestrogen genistein (G) and/or the antiandrogen vinclozolin (V) at 1 mg/kg-d, alone or in association. Using several approaches, we found that G- and GV-exposed rats displayed significantly greater epithelial branching and proliferation, wider terminal end buds than controls at PND35, as well as ductal hyperplasia and periductal fibrosis. Focal branching defects were present in V-exposed rats. An increased ER and AR expression was observed in G- and CV- as compared to V-exposed rats at PND35. Surprisin…