Search results for "melanin."
showing 8 items of 68 documents
Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin
2015
Gabriel Serrano,1 Patricia Almudéver,2 Juan M Serrano,3 Julio Cortijo,2 Carmen Faus,1 Magda Reyes,1 Inmaculada Expósito,3 Ana Torrens,3 Fernando Millán1 1Clínica Dermatológica Serrano, 2Department of Pharmacology, University of Valencia, 3Research and Development Department, Sesderma Laboratories, Valencia, Spain Abstract: Encapsulation of chemicals in liposomes and microneedling are currently used techniques to enhance the penetration of several substances through skin and hair. In this study, we apply a liposomal melanin–fluorescein compound to an ex vivo model of human skin, using a new electrical microneedling device (Nano…
Data from: Carry-over effects of conditions at the wintering grounds on breeding plumage signals in a migratory bird: roles of phenotypic plasticity …
2016
To understand the consequences of ever-changing environment on the dynamics of phenotypic traits, distinguishing between selection processes and individual plasticity is crucial. We examined individual consistency/plasticity in several male secondary sexual traits expressed during the breeding season (white wing and forehead patch size, UV reflectance of white wing patch and dorsal melanin colouration) in a migratory pied flycatcher (Ficedula hypoleuca) population over an 11-year period. Furthermore, we studied carry-over effects of three environmental variables (NAO, a climatic index; NDVI, a vegetation index; and rainfall) at the wintering grounds (during pre-breeding moult) on the expres…
Latanoprost-induced iris darkening: a morphometric study of human peripheral iridectomies.
2003
Abstract Purpose. This microscopic study was undertaken to compare the melanocytes of peripheral iridectomy specimens from two eyes that had latanoprost-induced iris darkening (LIID) with iridectomies taken from the fellow untreated eyes. Methods. The two patients in this study were the ones who underwent LIID in the latanoprost treated eye from a series of 17 patients requiring bilateral trabeculectomy. The first trabeculectomy procedure provided a control peripheral iridectomy for each patient, whereas the second eye was treated with once daily 50 μg ml−1 latanoprost drops for 6 months. The four peripheral iridectomy specimens from the two LIID patients were subjected to quantitative morp…
Histology and Fine Structure of the Iris and Outflow System Following Latanoprost Therapy
2002
Latanoprost therapy can lead to iris darkening in susceptible individuals, particularly those with hazel eyes. Concerns have been raised about whether latanoprost, and for that matter other prostanoids, may have a harmful effect on the iris. In addition, it is unknown whether latanoprost causes increased pigmentation of the outflow pathways that might eventually lead to blockage and a type of pigmentary glaucoma. The present study summarizes findings from the authors' own laboratories on the effects of latanoprost as seen by light and electron microscopy of the iris and outflow tissues and reviews the as yet limited, relevant literature. The findings support the proposal that latanoprost-in…
Spotlight on fundus autofluorescence.
2018
Fundus autofluorescence (FAF) imaging is based on the fluorescence from ocular endogenous fluorophores located in the retinal pigment epithelium and choroid, mainly lipofuscin and melanin. It is a noninvasive technique that provides information about the spatial distribution of lipofuscin/melanin and retinal pigment epithelium health status. An overview about the fluorophores responsible for FAF imaging and the usefulness of FAF imaging in the noninvasive assessment and monitoring of retinal diseases, such as age-related macular degeneration, diabetic retinopathy, diabetic macular edema, central serous chorioretinopthy, retinitis pigmentosa and retinal dystrophies, are discussed in this rev…
Responses to ultraviolet radiation in larval pike, Esox lucius, of two origins and ages
2007
Ultraviolet radiation (UVR)-induced mortality and behavioural disorder were studied in larval northern pike of two origins and ages. Newly hatched larvae of two differently coloured populations and six-day-old larvae of one population were exposed to four fluence rates of UVR, resulting in total doses from 11.5 to 63 kJ m–2, and monitored for mortality and behaviour. The rate of mortality and the severity of behavioural disorder differed by origin and age of the animals, but the effect was fluence-rate dependent. Total melanin concentration of newly hatched larvae was measured to assess if sensitivity to UVR correlated with pigmentation, but no differences in melanin concentration between l…
Kadmiumaltistuksen havaitseminen Hydropsyche pellucidula -vesiperhostoukilla (Trichoptera: Hydropsychidae) hyperspektrikuvantamisen ja kidusvaurioide…
2017
Metallipäästöt aiheuttavat vesistöissä eliöyhteisöille monenlaisia haittavaikutuksia, joita voidaan tutkia bioindikaattori- eli ilmentäjälajimenetelmin. Vesiperhostoukkia (Trichoptera) on käytetty virtavesien metallisaastumisen indikaattoreina, sillä ne kestävät metallialtistusta suhteellisen hyvin, mutta altistuksen seurauksena toukilla voi esiintyä morfologisia muutoksia, kuten kidusvaurioita tai pintakudoksen tummumista. Koska toisaalta vierasaineiden kudospitoisuusmittaus on usein työlästä ja toisaalta rakenteellisten muutosten arviointi altis subjektiiviselle harhalle, tavoitteenani oli kehittää objektiivinen ja kustannustehokas tapa selvittää metallialtistusta ja sen vaikutuksia pohja…
Comparative transcriptomics of albino and warningly‐coloured caterpillars
2021
Abstract Coloration is perhaps one of the most prominent adaptations for survival and reproduction of many taxa. Coloration is of particular importance for aposematic species, which rely on their coloring and patterning acting as a warning signal to deter predators. Most research has focused on the evolution of warning coloration by natural selection. However, little information is available for color mutants of aposematic species, particularly at the genomic level. Here, I compare the transcriptomes of albino mutant caterpillars of the aposematic wood tiger moth (Arctia plantaginis) to those of their full sibs having their distinctive orange‐black warning coloration. The results showed >29…