Search results for "methodologies"

showing 10 items of 2106 documents

Shared genetic etiology between alcohol dependence and major depressive disorder

2018

Supplemental Digital Content is available in the text.

Male0301 basic medicineOncologyAlcoholism/geneticsMultifactorial Inheritancealcohol dependenceMedizinGenome-wide association study0302 clinical medicineRisk FactorsGermanyMedicineGenetics (clinical)Brief ReportRegression analysisAlcoholismPsychiatry and Mental healthpolygenic risk scoresMeta-analysisComputingMethodologies_DOCUMENTANDTEXTPROCESSINGRegression AnalysisMajor depressive disorderdisease comorbidityDepressive Disorder Major/geneticsmedicine.medical_specialtyBFPolymorphism Single Nucleotide03 medical and health sciencespsychiatric genomics consortiumInternal medicineGeneticsHumansGenetic Predisposition to Diseaseddc:610Biological PsychiatryDepressive Disorder Majormajor depressive disorderbusiness.industryAlcohol dependenceCase-control studymedicine.diseaseComorbidity030104 developmental biologySample size determinationCase-Control Studiesgenome-wide association studiesRC0321business030217 neurology & neurosurgeryGenome-Wide Association Study
researchProduct

Author Correction: Binge Drinking among adolescents is related to the development of Alcohol Use Disorders: results from a Cross-Sectional Study

2018

Binge drinking (BD) is a common pattern of alcohol consumption among adolescents. At present few data are available on the possible relationship between BD and alcohol use disorders (AUD) in adolescents. The aim of this study was to assess the prevalence of BD and relationship between BD behavior and AUD among adolescents. A total of 2704 students attending 10 purposively selected high schools from three Italian provinces were surveyed. Questionnaires regarding socio-demographic data, pattern and amount of alcohol intake, smoking habits, use of illicit drugs, and physical activity were administered. AUD and affective disorders were also evaluated. Alcohol intake was reported by 2126 partici…

MaleAdolescentAlcohol DrinkingCross-sectional studylcsh:MedicineBinge drinkingAlcoholBinge DrinkingYoung Adult03 medical and health scienceschemistry.chemical_compound0302 clinical medicineSurveys and QuestionnairesEnvironmental healthPrevalenceHumanslcsh:ScienceAuthor CorrectionStudentsSchoolsMultidisciplinaryEthanollcsh:R030227 psychiatryAlcoholismCross-Sectional StudiesItalySocioeconomic FactorschemistryComputingMethodologies_DOCUMENTANDTEXTPROCESSINGlcsh:QFemalePsychology030217 neurology & neurosurgeryScientific Reports
researchProduct

Hearing in Real-Life Environments (HERE) : Structure and Reliability of a Questionnaire on Perceived Hearing for Older Adults

2019

Supplemental Digital Content is available in the text.

MaleAgingIntraclass correlationHealth StatusvanhuksetAudiologyIntelligibility (communication)01 natural sciencesspeech perception0302 clinical medicineHearingSurveys and Questionnaires030223 otorhinolaryngology010301 acousticshuonokuuloisuusAged 80 and overSpeech perceptionikäkuulota3142Social ParticipationkuuloHearing levelTest scoreComputingMethodologies_DOCUMENTANDTEXTPROCESSINGAuditory PerceptionFemalemedicine.symptomPsychologyikääntyneetResearch Articlemedicine.medical_specialtySpeech perceptionHearing loss03 medical and health sciencesSpeech and HearingCronbach's alpha0103 physical sciencesmedicineotorhinolaryngologic diseasesHumansSound LocalizationHearing Lossquestionnaire validationOrientation SpatialAgedagingReproducibility of ResultsQuestionnaire validationta3125ikääntyminenOtorhinolaryngologyhearingStandardized coefficientQuality of LifeSelf ReportFactor Analysis StatisticalCOSMIN criteria
researchProduct

Leisure-Time and Occupational Physical Activity Associates Differently with Epigenetic Aging

2021

Supplemental digital content is available in the text.

MaleAgingLeisure timeliikuntaEpigenesis Genetic0302 clinical medicineTwins DizygoticMedicineOrthopedics and Sports MedicineYoung adult315 Sport and fitness sciencesAge FactorsMETHYLATIONMiddle AgedDNA-metylaatioepigenetiikkaComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleSmoking statusSMOKINGfyysinen aktiivisuusAdultPhysical activityPhysical Therapy Sports Therapy and RehabilitationBIOLOGICAL AGINGYoung Adult03 medical and health sciencesLeisure ActivitiesSex FactorsHumansEpigeneticsExerciseOccupational HealthAgedModels GeneticBasic Sciencesbusiness.industrydNaMTwins Monozygotic030229 sport sciencesDNA MethylationTwin studyfyysinen kuormittavuusikääntyminentyön kuormittavuusbusinessLifestyle habitshuman activitiesQUANTITATIVE GENETICSDemography
researchProduct

SARS CoV2 infection _The longevity study perspectives

2021

Graphical abstract

MaleAgingssRNA single-stranded RNARFLP restriction fragment length polymorphismHSPs heat shock proteinsReviewPTMs post-translational modificationsSevere Acute Respiratory SyndromeBiochemistryHIV-1 human immunodeficiency virus-1TNF-α tumor necrosis factor-αEC endothelial cells0302 clinical medicineFluAV influenza A virusI insertionMedicineIFN-γ interferon-γDIC disseminated intravascular coagulationPCR Polymerase Chain Reactionmedia_commonAged 80 and overLongevityRBD receptor-binding domainNeurologyLongevity modelMI myocardial infarctionNK natural killerhPIV2 human parainfluenza virus type 2media_common.quotation_subjectResearching genetic basis of resistance and potential pharmacological targetsLongevityDBP diastolic blood pressureNF-Kb nuclear transcription factor kBRANTES regulated upon activation normal T cell expressed and secretedMphi human macrophages03 medical and health sciencesCox 2 cyclooxygenase 2ORF open reading framePT prothrombin timeSettore MED/05 - Patologia ClinicaHumansMolecular BiologyInflammatory genesARDS acute respiratory distress syndromeNO nitric oxideD deletionCpGIs CpG islandsT2DM type 2 diabetes mellitusmedicine.diseaseFDP fibrin degradation products030104 developmental biologySARS CoV2 severe acute respiratory syndrome Coronavirus 2 virusImmunologyBMI body max indexItalian nonagenarians/centenariansRSV respiratory syncytial virusComplication030217 neurology & neurosurgeryMAPK mitogen-activated protein kinaseIP-10 IFN-γ -Inducible Protein 1040301 basic medicineAT1R activity of angiotensin 1 receptorsDCs dentritic cellsSSCP single strand conformation polymorphismACE/DD polymorphism of the angiotensin converting enzymeFGF21 fibroblast growth factor 21TLR4 toll-like receptor 4NAD nicotinamide adenine dinucleotideACE angiotensin-I converting enzymeAT2R activity of angiotensin 2 receptorsCOVID-19 Coronavirus disease 2019Respiratory distressACE2 angiotensin converting enzyme 2MKP-1 mitogen-activated protein kinase phosphatase-1 ()PD protease domainSNP single nucleotide polymorphismEH essential hypertensionTNFR tumor necrosis factor receptorINR international normalized ratio of the prothrombin timePAI-1 plasminogen activator inhibitor-1Ang angiotensinLPS lipopolysaccharideMCP1 monocyte chemoattractant protein-1medicine.symptomaPTT partial thromboplastin timeBiotechnologyDUSP1 dual specificity phosphatase 1Coronavirus disease 2019 (COVID-19)PC prostate cancerRAS renin-angiotensin aldosterone systemCCR5Δ32 genetic variant of chemokine receptorCOVID-19 Researching genetic basis of resistance and potential pharmacological targets Italian nonagenarians/centenarians Longevity modelAsymptomaticSARS-1 severe acute respiratory syndrome virus 1SIRT-1 Sirtuin 1Th1 t-helper lymphocyte type 1Immune systemROS reactive oxygen speciesTGF-β transforming growth factor betaET-1 endothelin-1ComputingMethodologies_COMPUTERGRAPHICSADAM-17 metallopeptidase domain 17business.industrySARS-CoV-2SBP systolic blood pressureCOVID-19HDACs histone deacetylasesComorbidityImmune Systembusiness5-LO lipoxygenase 5Ageing Research Reviews
researchProduct

Polygenic Score for Physical Activity Is Associated with Multiple Common Diseases

2021

Supplemental digital content is available in the text.

MaleEpidemiologyPhysical fitnessType 2 diabetesDiseaseLogistic regressionTYPE 2 DIABETESOrthopedics and Sports Medicine315 Sport and fitness sciencesPREDICTORSChildkohorttitutkimusFinlandAged 80 and oversairastavuusHERITABILITYGenetic PleiotropyriskitekijätMiddle AgedCardiovascular DiseasesChild PreschoolCohortComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleSMOKINGgeneettiset tekijätfyysinen aktiivisuusAdultGenetic Markerskuolleisuusmedicine.medical_specialtyAdolescentGenotypePhysical Therapy Sports Therapy and RehabilitationEXERCISEpitkittäistutkimusLower riskRisk AssessmentYoung AdultMetabolic DiseasesInternal medicineClinical Decision RulesBENEFITSmedicineHumansAgedbusiness.industryRISK SCORESCardiometabolic Risk FactorsInfantOdds ratiomedicine.diseaseGENEBODY-MASS INDEXLogistic ModelsCase-Control StudiesLinear Modelssydän- ja verisuonitauditbusinessBody mass indexGenome-Wide Association Study
researchProduct

Risk of Lung Cancer Mortality in Nuclear Workers from Internal Exposure to Alpha Particle-emitting Radionuclides

2017

Supplemental Digital Content is available in the text.

MaleLung NeoplasmsEpidemiology[SDV]Life Sciences [q-bio]chemistry.chemical_elementRadonSubstàncies radioactivesExtraction and Processing Industry030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineBelgiumRisk FactorsEnvironmental healthOccupational ExposureMortalitatMedicineHumansLung Neoplasms/mortality; Neoplasms Radiation-Induced/mortality; Occupational Diseases/mortality; Radiation Exposure/adverse effectsMortalityLung cancerRadiometryCarcinogenCancerAgedRadionuclidebusiness.industryAlpha particleMiddle Agedmedicine.diseaseAlpha ParticlesPlutoniumUnited Kingdom3. Good healthchemistry030220 oncology & carcinogenesisCase-Control StudiesComputingMethodologies_DOCUMENTANDTEXTPROCESSINGCàncer de pulmóUraniumFemaleOccupational exposureFranceLung cancerbusinessNuclear medicineRadioactive substances
researchProduct

Polygenic Risk Scores and Physical Activity

2020

Supplemental digital content is available in the text.

MaleMultifactorial InheritanceEpidemiologyheritabilityNorthern finlandDISEASEhidden heritability0302 clinical medicineRisk FactorsMISSING HERITABILITYAccelerometryMedicineOrthopedics and Sports Medicine315 Sport and fitness sciencesgeneskrooniset tauditFinlandAged 80 and overeducation.field_of_studyFramingham Risk ScoreBIRTH COHORTexerciseHERITABILITYObjective measurementriskitekijätMiddle Aged3. Good healthComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleHEALTHgeenitutkimusBirth cohortfyysinen aktiivisuusAdultSingle variableAdolescentGenotypePopulationPhysical activityEXERCISEPhysical Therapy Sports Therapy and RehabilitationFitness TrackersGENOTYPE IMPUTATIONPolymorphism Single Nucleotideperinnöllinen alttiusYoung Adult03 medical and health sciencesHumansGENOME-WIDE ASSOCIATIONgeneeducationperinnöllisyysAgedgeenitbusiness.industryHIDDEN HERITABILITY030229 sport sciencesGENEperimäPolygenic risk scoreSelf ReportbusinessGenome-Wide Association StudyDemographyMedicine & Science in Sports & Exercise
researchProduct

Do handwritten words magnify lexical effects in visual word recognition?

2016

Published online: 27 Oct 2015 An examination of how the word recognition system is able to process handwritten words is fundamental to formulate a comprehensive model of visual word recognition. Previous research has revealed that the magnitude of lexical effects (e.g., the word-frequency effect) is greater with handwritten words than with printed words. In the present lexical decision experiments, we examined whether the quality of handwritten words moderates the recruitment of top-down feedback, as reflected in word-frequency effects. Results showed a reading cost for difficult-to-read and easy-to-read handwritten words relative to printed words. But the critical finding was that difficul…

MalePHYSIOLOGY (MEDICAL)HandwritingVocabularyPSYCHOLOGY EXPERIMENTALPhysiologycomputer.software_genreVocabulary0302 clinical medicineHandwritingReading (process)Word frequencyGeneral Psychologymedia_common05 social sciencesHandwritten wordsGeneral MedicineLinguisticsSemanticsNeuropsychology and Physiological PsychologyNEUROPSYCHOLOGY AND PHYSIOLOGICAL PSYCHOLOGYComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemalePsychologyNatural language processingUniversitiesmedia_common.quotation_subjectExperimental and Cognitive PsychologySemantics050105 experimental psychologyIntelligent word recognitionPSYCHOLOGY03 medical and health sciencesPhysiology (medical)Reaction TimeLexical decision taskHumans0501 psychology and cognitive sciencesStudentsPHYSIOLOGYAnalysis of Variancebusiness.industryVisual-word recognitionRecognition PsychologyWord lists by frequencyComputingMethodologies_PATTERNRECOGNITIONReadingWord recognitionArtificial intelligencebusinesscomputer030217 neurology & neurosurgeryQuarterly Journal of Experimental Psychology
researchProduct

Fermented Milk Consumption and Common Infections in Children Attending Day-Care Centers: A Randomized Trial

2016

Supplemental Digital Content is available in the text

MalePediatricsmedicine.medical_specialtyLactobacillus caseiCultured Milk ProductsDay careCommunicable Diseaseslaw.invention03 medical and health sciences0302 clinical medicineDouble-Blind MethodRandomized controlled trialrespiratory infectionlaw030225 pediatricsLactobacillus casei CNCM I-1518Cultured Milk ProductsmedicineAnimalsHumans030212 general & internal medicineChildbiologybusiness.industryIncidenceProbioticsIncidence (epidemiology)rhinopharyngitisOriginal Articles: NutritionGastroenterologyfood and beveragesChild Day Care Centersbiology.organism_classificationClinical trialLacticaseibacillus caseiMilkMulticenter studyCommon infectious diseasesChild PreschoolFermentationPediatrics Perinatology and Child HealthComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemalebusinessLactobacillus caseigastrointestinal infectionJournal of Pediatric Gastroenterology & Nutrition
researchProduct