Search results for "mismatch"
showing 10 items of 345 documents
Hippocampal event-related potentials to pitch deviances in an auditory oddball situation in the cat: experiment I.
1995
Hippocampal event-related potentials (ERP) in the areas CA1, CA3, and dentate fascia (Df) were recorded in cats during an oddball situation when pitch deviant tones occurred in a series of standard tones. When difference waves were calculated by subtracting ERPs to the standard tones from those to the deviant tones, no clear N40d, corresponding to a cat analogue of the human mismatch negativity (MMN) observed in earlier studies, could be detected. Instead, a prominent later negativity (N130d) was observed. A possible extra-hippocampal source of the process reflected by the MMN-like negativity, and a relation between an orienting response (OR) and the N130d are discussed.
Music training enhances rapid neural plasticity of N1 and P2 source activation for unattended sounds
2012
Neurocognitive studies have demonstrated that long-term music training enhances the processing of unattended sounds. It is not clear, however, whether music training also modulates rapid (within tens of minutes) neural plasticity for sound encoding. To study this phenomenon, we examined whether adult musicians display enhanced rapid neural plasticity compared to non-musicians. More specifically, we compared the modulation of P1, N1, and P2 responses to standard sounds between four unattended passive blocks. Among the standard sounds, infrequently presented deviant sounds were presented (the so-called oddball paradigm). In the middle of the experiment (after two blocks), an active task was p…
Explicit behavioral detection of visual changes develops without their implicit neurophysiological detectability
2012
Change blindness is a failure of reporting major changes across consecutive images if separated, e.g., by a brief blank interval. Successful change detection across interrupts requires focal attention to the changes. However, findings of implicit detection of visual changes during change blindness have raised the question of whether the implicit mode is necessary for development of the explicit mode. To this end, we recorded the visual mismatch negativity (vMMN) of the event-related potentials (ERPs) of the brain, an index of implicit pre-attentive visual change detection, in adult humans performing an oddball-variant of change blindness flicker task. Images of 500 ms in duration were prese…
Valenza e insegnamento della lingua straniera
2015
This work deals with valency, a key syntactic notion whose chemistry-inspired label was established by Lucien Tesnière (1959), one of the most well-known contributors to the Prague Linguistic Circle. We will concentrate on two questions: (a) to what extent does valency play a role in Second Language Learning (SLL)?; and (b) what role should the use of valency play in language teaching practices? This paper will provide answers to these questions and propose reasons for motivating the use of valency in SLL.
Interactions of membranes with coarse-grain proteins: a comparison
2012
We study the interactions between lipid bilayers and rigid transmembrane proteins by Monte Carlo simulations of generic coarse-grain models. Different popular protein models are considered and compared with each other, and key parameters such as the hydrophobicity and the hydrophobic mismatch are varied systematically. Furthermore, the properties of the membrane are manipulated by applying different tensions. The response of the membrane to the insertion of single proteins is found to be mostly generic and independent of the choice of the protein model. Likewise, the orientational distributions of single proteins depend mainly on the hydrophobic mismatch and the hydrophobicity of the protei…
Neural phoneme discrimination in variable speech in newborns – associations with dyslexia risk and later language skills
2023
AbstractA crucial skill in infant language acquisition is learning of the native language phonemes. This requires the ability to group complex sounds into distinct auditory categories based on their shared features. Problems in phonetic learning have been suggested to underlie language learning difficulties in dyslexia, a developmental reading-skill deficit. We investigated auditory abilities important for language acquisition in newborns with or without a familial risk for dyslexia with electrophysiological mismatch responses (MMRs). We presented vowel changes in a sequence of acoustically varying vowels, requiring grouping of the stimuli to two phoneme categories. The vowel changes elicit…
Value of Combined PET Imaging with [18F]FDG and [68Ga]Ga-PSMA-11 in mCRPC Patients with Worsening Disease during [177Lu]Lu-PSMA-617 RLT
2021
Despite the promising results of prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) in metastatic castration-resistant prostate cancer (mCRPC), some patients show worsening disease during PSMA-RLT. We investigated the value of combined [18F]FDG and [68Ga]Ga-PSMA-11 PET imaging in this setting. In n = 29 mCRPC patients with worsening disease after a median of four cycles of [177Lu]Lu-PSMA-617 RLT, combined [18F]FDG and [68Ga]Ga-PSMA-11 PET imaging was performed to detect [18F]FDG-avid lesions with low or no PSMA expression (mismatch lesions). To evaluate prognostic implication of mismatch, survival analyses regarding presence, location, and [18F]FDG PET-derived para…
DNA integrity in diagnosis of premalignant lesions
2020
Background Carcinogenesis is a dynamic process which traditional biopsying can not keep up with. Saliva as fluid in the vicinity of the tumor can offer better insights to this process. This study aimed to identify the accuracy of salivary DNA integrity index in differentiating between oral premalignant lesions and oral cancer. Material and Methods This phase II diagnostic test accuracy study included 93 patients divided into three groups: 30 oral cancer patients, 33 patients with oral premalignant lesions divided into 21 oral lichen planus patients and 12 patients with leukoplakia and 30 normal individuals who acted as controls. Oral rinse was collected from all participants and they all un…
Ikääntymisen vaikutus visuaaliseen prosessointiin
2012
Tämän pro gradu -tutkielman tarkoituksena oli selvittää aivojen automaattisen muutoksen havaitsemisjärjestelmän toimintaa visuaalisessa järjestelmässä tapahtumasidonnaisten herätevasteiden (ERP) avulla. Lisäksi tutkielmassa haluttiin selvittää ikääntymisen mahdollisia vaikutuksia tämän järjestelmän toimintaan vertailemalla toisiinsa terveiden nuorten aikuisten (n=19, 22-27 vuotta) ja ikääntyneiden (n=10, 69-95 vuotta) visuaalisia herätevasteita N2- ja P3 -komponenteissa. Visuaalinen herätevaste, jota tutkielmassa tarkasteltiin, oli poikkeavuusnegatiivisuus (mismatch negativity, MMN). Tutkielmassa ERP:t rekisteröitiin elektroenkefalografialla (EEG) ja passiivisen oddball -paradigman avulla. …
Upper thermal threshold of Lepidurus arcticus (Branchiopoda, Notostraca) in lakes on the southern outreach of its distribution range
2021
Qvenild T, Fjeld E, Fjellheim A, Hammar J, Hesthagen T and Lakka H-K. 2021. Upper thermal threshold of Lepidurus arcticus (Branchiopoda, Notostraca) in lakes on the southern outreach of its distribution range. Fauna norvegica 41: 50–88. The Arctic tadpole shrimp Lepidurus arcticus has a circumpolar distribution and the Scandes (Fennoscandian Mountains) marks its southernmost limit in Europe. Within this area, 391 natural and 88 regulated lakes with L. arcticus have been identified, of which 87% are above the treeline. The lakes hosting L. arcticus decrease in altitude from south to north, which results from its temperature preferences. The majority of the locations are at a lower lake air t…