Search results for "models"

Comparison between two different cardiovascular models during a hemorrhagic shock scenario

2020

Hemorrhagic shock is a form of hypovolemic shock determined by rapid and large loss of intravascular blood volume and represents the first cause of death in the world, whether on the battlefield or in civilian traumatology. For this, the ability to prevent hemorrhagic shock remains one of the greatest challenges in the medical and engineering fields. The use of mathematical models of the cardiocirculatory system has improved the capacity, on one hand, to predict the risk of hemorrhagic shock and, on the other, to determine efficient treatment strategies. In this paper, a comparison between two mathematical models that simulate several hemorrhagic scenarios is presented. The models considere…

Sexually selected traits evolve positive allometry when some matings occur irrespective of the trait

2014

Positive allometry of secondary sexual traits (whereby larger individuals have disproportionally larger traits than smaller individuals) has been called one of the most pervasive and poorly understood regularities in the study of animal form and function. Its widespread occurrence is in contrast with theoretical predictions that it should evolve only under rather special circumstances. Using a combination of mathematical modeling and simulations, here we show that positive allometry is predicted to evolve under much broader conditions than previously recognized. This result hinges on the assumption that mating success is not necessarily zero for males with the lowest trait values: for examp…

Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy

2017

Background: Inhibition of activin/myostatin pathway has emerged as a novel approach to increase muscle mass and bone strength. Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that leads to progressive muscle degeneration and also high incidence of fractures. The aim of our study was to test whether inhibition of activin receptor IIB ligands with or without exercise could improve bone strength in the mdx mouse model for DMD. Methods: Thirty-two mdx mice were divided to running and non-running groups and to receive either PBS control or soluble activin type IIB-receptor (ActRIIB-Fc) once weekly for 7 weeks. Results: Treatment of mdx mice with ActRIIB-Fc resulted in significantly…

Data from: Choosy beetles: how host trees and southern boreal forest naturalness may determine dead wood beetle communities

2021

See methods section of paper for detailed information on dataset and sources; briefly, these .csv files includes numbers of each beetle species captured at all sites used in the project, as well as information about each site and about each species. Data from: Choosy beetles: how host trees and southern boreal forest naturalness may determine dead wood beetle communities Ryan C. Burner, Tone Birkemoe, Jörg G. Stephan, Lukas Drag, Jörg Muller, Otso Ovakainen, Mária Potterf, Olav Skarpaas, Tord Snall, Anne Sverdrup-Thygeson Forest Ecology and Management, 2021 From abstract of paper: Wood-living beetles make up a large proportion of forest biodiversity, and contribute to important ecosystem se…

On the origin and diversification of Podolian cattle breeds: testing scenarios of European colonization using genome-wide SNP data

2021

AbstractBackgroundDuring the Neolithic expansion, cattle accompanied humans and spread from their domestication centres to colonize the ancient world. In addition, European cattle occasionally intermingled with both indicine cattle and local aurochs resulting in an exclusive pattern of genetic diversity. Among the most ancient European cattle are breeds that belong to the so-called Podolian trunk, the history of which is still not well established. Here, we used genome-wide single nucleotide polymorphism (SNP) data on 806 individuals belonging to 36 breeds to reconstruct the origin and diversification of Podolian cattle and to provide a reliable scenario of the European colonization, throug…

Green Roofs as Effective Tools for Improving the Indoor Comfort Levels of Buildings—An Application to a Case Study in Sicily

2020

In the line of pursuing better energy efficiency in human activities that would result in a more sustainable utilization of resources, the building sector plays a relevant role, being responsible for almost 40% of both energy consumption and the release of pollutant substances in the atmosphere. For this purpose, techniques aimed at improving the energy performances of buildings&rsquo

Business models and opportunity creation: How IT entrepreneurs create and develop business models under uncertainty

2016

How can entrepreneurs develop business models for markets in which the technology is constantly changing – or create business models for markets that do not exist? These are fundamental questions for information technology (IT) entrepreneurs, and for information systems (IS) scholars who seek to develop a theoretical understanding of business models. The case study presented in this paper addressed these questions, demonstrating how a small software firm developed its business model over a 15-year period in cloud gaming markets. Based on the empirical findings, a preliminary theoretical model is presented. The aim of the model is to increase scholarly understanding of how business models ar…

Business-to-business service quality assessment in professional wine events: the case of Vinitaly

2014

Haematopoietic stem cell transplantation in the treatment of autoimmune diseases: current experience from an international data base.

2000

Predicting human performance in interactive tasks by using dynamic models

2017

The selection of an appropriate sequence of activities is an essential task to keep student motivation and foster engagement. Usually, decisions in this respect are made by taking into account the difficulty of the activities, in relation to the student's level of competence. In this paper, we present a dynamic model that aims to predict the average performance of a group of students at solving a given series of maths problems. The system takes into account both student- and task-related features. This model was built and validated by using the data gathered in an experimental session that involved 64 participants solving a sequence of 26 arithmetic problems. The data collected from the fir…