Search results for "modified"
showing 10 items of 585 documents
Biochemistry and genetics of insect resistance to Bacillus thuringiensis.
2001
▪ Abstract Bacillus thuringiensis (Bt) is a valuable source of insecticidal proteins for use in conventional sprayable formulations and in transgenic crops, and it is the most promising alternative to synthetic insecticides. However, evolution of resistance in insect populations is a serious threat to this technology. So far, only one insect species has evolved significant levels of resistance in the field, but laboratory selection experiments have shown the high potential of other species to evolve resistance against Bt. We have reviewed the current knowledge on the biochemical mechanisms and genetics of resistance to Bt products and insecticidal crystal proteins. The understanding of th…
Survival of two strains of Phthorimaea operculella (Lepidoptera: Gelechiidae) reared on transgenic potatoes expressing a Bacillus thuringiensis cryst…
1998
[Otros] Survie de deux souches de Phthorimaea operculella (Lepidoptera : Gelechiidae) élevées sur des pommes de terre transgéniques exprimant la protéine CrylAb de Bacillus thuringiensis. Deux populations de Phthorimaea operculella (Zeller), l'une supposée résistante au DipelTM (une préparation commerciale de delta-endotoxines de Bacillus thuringiensis) et l'autre sensible, ont été cultivées sur quatre cultivars de pomme de terre, deux transgéniques de première génération, exprimant la protéine CrylAb de Bacillus thuringiensis, et deux non transformés. La population de papillons considérée comme résistante a présenté une mortalité inférieure à celle de l'autre population, mais n'était pas v…
The use of porous and surface modified silicas as drug delivery and stabilizing agents
1983
(1983). The use of porous and surface modified silicas as drug delivery and stabilizing agents. Drug Development and Industrial Pharmacy: Vol. 9, No. 1-2, pp. 69-91.
Apurinic acid, a modified DNA with anticancer activity
1971
Apurinsaure, ein purinfreies hochmolekulares Desoxyribonukleinsaure-Derivat, hemmt das Wachstum des menschlichen Kolontumors GW-77 und das amelanotsiche Melanom des Hamsters.
Cosmological data analysis of f(R) gravity models
2009
A class of well-behaved modified gravity models with long enough matter domination epoch and a late-time accelerated expansion is confronted with SNIa, CMB, SDSS, BAO and H(z) galaxy ages data, as well as current measurements of the linear growth of structure. We show that the combination of geometrical probes and growth data exploited here allows to rule out f(R) gravity models, in particular, the logarithmic of curvature model. We also apply solar system tests to the models in agreement with the cosmological data. We find that the exponential of the inverse of the curvature model satisfies all the observational tests considered and we derive the allowed range of parameters. Current data s…
Nonsingular Black Holes in $f(R)$ Theories
2015
We study the structure of a family of static, spherically symmetric space-times generated by an anisotropic fluid and governed by a particular type of $f(R)$ theory. We find that for a range of parameters with physical interest, such solutions represent black holes with the central singularity replaced by a finite size wormhole. We show that time-like geodesics and null geodesics with nonzero angular momentum never reach the wormhole throat due to an infinite potential barrier. For null radial geodesics, it takes an infinite affine time to reach the wormhole. This means that the resulting space-time is geodesically complete and, therefore, nonsingular despite the generic existence of curvat…
Rotating black holes in Eddington-inspired Born-Infeld gravity: an exact solution
2020
We find an exact, rotating charged black hole solution within Eddington-inspired Born-Infeld gravity. To this end we employ a recently developed correspondence or {\it mapping} between modified gravity models built as scalars out of contractions of the metric with the Ricci tensor, and formulated in metric-affine spaces (Ricci-Based Gravity theories) and General Relativity. This way, starting from the Kerr-Newman solution, we show that this mapping bring us the axisymmetric solutions of Eddington-inspired Born-Infeld gravity coupled to a certain model of non-linear electrodynamics. We discuss the most relevant physical features of the solutions obtained this way, both in the spherically sym…
The virial theorem and the dark matter problem in hybrid metric-Palatini gravity
2012
Hybrid metric-Palatini gravity is a recently proposed theory, consisting of the superposition of the metric Einstein-Hilbert Lagrangian with an f(R) term constructed a la Palatini. The theory predicts the existence of a long-range scalar field, which passes the Solar System observational constraints, even if the scalar field is very light, and modifies the cosmological and galactic dynamics. Thus, the theory opens new possibilities to approach, in the same theoretical framework, the problems of both dark energy and dark matter. In this work, we consider the generalized virial theorem in the scalar-tensor representation of the hybrid metric-Palatini gravity. More specifically, taking into ac…
Arabidopsis copper transport protein COPT2 participates in the crosstalk between iron deficiency responses and low phosphate signaling
2013
[EN] Copper and iron are essential micronutrients for most living organisms because they participate as cofactors in biological processes, including respiration, photosynthesis, and oxidative stress protection. In many eukaryotic organisms, including yeast (Saccharomyces cerevisiae) and mammals, copper and iron homeostases are highly interconnected; yet, such interdependence is not well established in higher plants. Here, we propose that COPT2, a high-affinity copper transport protein, functions under copper and iron deficiencies in Arabidopsis (Arabidopsis thaliana). COPT2 is a plasma membrane protein that functions in copper acquisition and distribution. Characterization of the COPT2 expr…
Paratransgenic manipulation of a tsetse microRNA alters the physiological homeostasis of the fly’s midgut environment
2021
Tsetse flies are vectors of parasitic African trypanosomes, the etiological agents of human and animal African trypanosomoses. Current disease control methods include fly-repelling pesticides, fly trapping, and chemotherapeutic treatment of infected people and animals. Inhibiting tsetse’s ability to transmit trypanosomes by strengthening the fly’s natural barriers can serve as an alternative approach to reduce disease. The peritrophic matrix (PM) is a chitinous and proteinaceous barrier that lines the insect midgut and serves as a protective barrier that inhibits infection with pathogens. African trypanosomes must cross tsetse’s PM in order to establish an infection in the fly, and PM struc…