Search results for "mof"
showing 10 items of 174 documents
Mycophenolate mofetil and enteric-coated mycophenolate sodium in the treatment of pemphigus vulgaris and pemphigus foliaceus.
2014
What is known and objective: Pemphigus is a severe, potentially life-threatening autoimmune blistering disease. The use of corticosteroids has dramatically improved the prognosis and changed its course. However, current morbidity of pemphigus is largely iatrogenic, caused by side effects of the long-term, high-dose corticosteroid therapy that is necessary to sustain disease control. In order to minimize side effects, a range of corticosteroid-sparing immunosuppressive agents have been introduced, including mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS). A systematic review was performed to evaluate the effectiveness of MMF and EC-MPS in the treatment of pemphig…
Pharmacokinetic evaluation of mycophenolate mofetil for pemphigus.
2011
Introduction: Pemphigus is an autoimmune blistering disease of the skin and mucous membranes characterized by the development of autoantibodies against the desmosomal proteins, desmoglein-1 and -3. Before the advent of corticosteroids, therapy was almost fatal. The introduction of high-dose corticosteroid therapy has reduced mortality rates to similar to 10%, but long-term use of steroids can lead to side effects, many of which are severe and associated with significant morbidity. Thus, the major goal of pemphigus therapy has been to reduce the patient's cumulative exposure to systemic corticosteroids. Over the last 2 decades, a range of corticosteroid-sparing immunosuppressive agents have …
Decomposition Process of Carboxylate MOF HKUST-1 Unveiled at the Atomic Scale Level
2016
HKUST-1 is a metal-organic framework (MOF) which plays a significant role both in applicative and basic fields of research, thanks to its outstanding properties of adsorption and catalysis but also because it is a reference material for the study of many general properties of MOFs. Its metallic group comprises a pair of Cu2+ ions chelated by four carboxylate bridges, forming a structure known as paddle-wheel unit, which is the heart of the material. However, previous studies have well established that the paddle-wheel is incline to hydrolysis. In fact, the prolonged exposure of the material to moisture promotes the hydrolysis of Cu-O bonds in the paddle-wheels, so breaking the crystalline n…
From 1D coordination polymers to Metal Organic Frameworks by the use of 2-pyridyl oximes.
2020
The synthesis and characterization of coordination polymers and metal&ndash
O analogiji i teoriji etimona u hebrejskome biblijskom leksiku
2012
Dans le débat sur l’iconicité du langage, l’une des questions qui se posent d’une manière récurrente est de savoir si les formations onomatopéiques représentent un principe primitif de formation des mots, si dans les premières formes du langage humain tous les signes ont été du type craquer, murmurer, etc., dont la plupart auraient ensuite perdu leur charge mimophonique. Saussure s’est prononcé contre toute théorie positive de la signification dans le domaine des sciences du langage, position qui a constitué pour longtemps une norme de travail en linguistique. Cet article traite des icônes auditives dans le lexique hébraïque de la Bible dont l’analogie phonation–référent est rendue manifest…
Polímeros de coordinación porosos como reactores químicos para nuevos materiales avanzados: química en espacios confinados
2022
The central aim of this PhD thesis is to develop synthetic procedures to construct metal organic-frameworks (MOFs) able to host/build up molecular-based species, such as metal ions with particular coordination environments, single atom catalysts (SACs), sub-nanometric metal clusters (SNMCs) and supramolecular coordination complexes (SCCs), otherwise hardly accessible, with high catalytic reactivity and in a multigram scale. The nature of the final assemblies has been characterised with a myriad of physical techniques, where taking advantage of the high crystallinity and structural robustness of the MOFs used as platforms, single-crsytal X-ray crystallography play a promienet role and provid…
Ādas hromoforu kartēšana, izmantojot divu momentuzņēmumu metodi
2018
Darba mērķis ir izstrādāt metodi, ar kuru īsā laika posmā var iegūt informāciju par hromoforu koncentrāciju sadalījumu ādā. Darbā tiek apskatītas vairākas ādas patoloģijas. Katra veidojuma analīzei tiek uzņemti divi attēli. Pirmais attēls tiek iegūts, ādu apgaismojot ar trīs dažādu viļņu garumu lāzeriem: 450nm, 525nm un 850nm. Savukārt otrs attēls tiek iegūts, ādu apgaismojot ar diviem dažādu viļņa garuma lāzeriem: 405nm un 656nm. Tālāk attēli tiek sadalīti R, G un B kanālos. Papildus tiek iegūti pieci references attēli, apgaismojot baltu lapu ar katru no lāzeriem. Sadalot arī šos attēlus R, G un B kanālos, rezultātā tiek iegūti 21 monohromatisks attēls, no kuriem tiek aprēķināti spektrālās…
I fondamenti etero/cisnormativi del discorso criminologico. Una breve riflessione storico-sociologica
2020
Tenendo conto di un approccio archeologico del sapere socio-criminologico, l’obiettivo principale del saggio è tentare di comprendere in che modo i discorsi socio-criminologici sugli LGBT si caratterizzino non tanto rispetto al loro oggetto privilegiato, quanto piuttosto in base al modo attraverso cui formano questi stessi oggetti; si tratta di analizzare, dunque, le modalità che organizzano storicamente i modelli culturali proiettati dai discorsi medico-legali-criminologici da intendersi prevalentemente come «pratiche che formano sistematicamente gli oggetti di cui parlano». In particolare, la costruzione della tipologia dell’“invertito” ha origine a partire dal discorso medico nella metà …