Search results for "molecular system"

Molecular systematics of two Mediterranean blenniid species from the genus Salaria (Perciformes, Blenniidae): Salaria basilisca and S. pavo

2016

Status and prospects of systems biology in grapevine research

2019

The cultivated grapevine, Vitis vinifera L., has gathered a vast amount of omics data throughout the last two decades, driving the imperative use of computational resources for its analysis and integration. Molecular systems biology arises from this need allowing to model and predict the emergence of phenotypes or responses in biological systems. Beyond single omics networks, integrative approaches associate the molecular components of an organism and combine them into higher order networks to model dynamic behaviors. Application of network-based methods in multi-omics data is providing additional resources to address important questions regarding grapevine fruit quality and composition. He…

Fullerene-Polymers: Synthesis, Properties and Applications

2009

Written by an outstanding team of experts in the interdisciplinary areas of research, this book is based on a new classification of the different types of fullerene polymers according to their chemical structures. It covers all aspects, from different classes, to their synthesis and applications in material science. Of great interest to polymer and synthetic chemists, but also for material scientists and industrial chemists.

Molecular evolution of the metazoan protein kinase C multigene family

1996

Protein kinases C (PKCs) comprise closely related Ser/Thr kinases, ubiquitously present in animal tissues ; they respond to second messengers, e.g., Ca2+ and/or diacylglycerol, to express their activities. Two PKCs have been sequenced from Geodia cydonium, a member of the lowest multicellular animals, the sponges (Porifera). One sponge G. cydonium PKC, GCPKC1, belongs to the ''novel'' (Ca2+-independent) PKC (nPKC) subfamily while the second one, GCPKC2, has the hall-marks of the ''conventional'' (Ca2+-dependent) PKC (cPKC) subfamily. The alignment of the Ser/Thr catalytic kinase domains, of the predicted aa sequences for these cDNAs with respective segments from previously reported sequence…

Sister species within the Triops cancriformis lineage (Crustacea, Notostraca)

2006

301 Korn, M., Marrone, F., Perez-Bote, J. L., Machado, M., Cristo, M., Cancela da Fonseca, L. & Hundsdoerfer, A. K. (2006). Sister species within the Triops cancriformis lineage (Crustacea, Notostraca). — Zoologica Scripta , 35 , 301–322. We investigated the phylogenetic relationships among the three presently recognized subspecies of the tadpole shrimp, Triops cancriformis , using mitochondrial 16S and 12S rDNA sequences. Our results indicate that the taxon is divided into two distinct lineages. One lineage is formed of T. c. cancriformis populations and samples from northern Spain that had been classified as T. c. simplex in the most recent literature. The second lineage comprises all pop…

IS CALORIMETRY A CRUCIAL TECHNIQUE FOR STUDYING INNOVATIVE NANOMATERIALS?

2012

It is well known that calorimetry is a powerful technique to determine the complete energetics of interaction processes. Unfortunately, over the years the calorimetry has been applied to restricted fields so that it has been underemployed in studying smart nanomaterials (polypseudorotaxanes, polymeric aggregates, surface functionalized nanoparticles, nanocomposites, etc.) to which a tremendous scientific interest has been recently addressed. Within this topic some relevant recent results from our laboratory will be described in the following. As concerns the supramolecular chemistry field, we exploited strategies to design stable and stimuli responsive polypseudorotaxanes based on cyclodext…

A Solution to the Problem of the Maximal Number of Symbols for Biomolecular Computer

2019

The authors present a solution to the problem of generating the maximum possible number of symbols for a biomolecular computer using restriction enzyme BbvI and ligase as the hardware, and transition molecules built of double-stranded DNA as the software. The presented solution offers an answer to the open question, in the algorithm form, of the maximal number of symbols for a biomolecular computer that makes use of the restriction enzyme BbvI.

Role of C–H···Au and Aurophilic Supramolecular Interactions in Gold–Thione Complexes

2014

The role of noncovalent gold–hydrogen and aurophilic interactions in the formation of extended molecular systems of gold complexes was studied. Three new gold compounds with a heterocyclic thione ligand N-methylbenzothiazole-2-thione (mbtt), namely, [AuCl(mbtt)] (1), [AuBr(mbtt)] (2), and [Au(mbtt)2][AuI2]1–n[I3]n (3), were synthesized and characterized. The halide ligand had a considerable effect on the complex structures and thus to noncovalent contacts. Intermolecular C–H···Au and aurophilic Au···Au contacts were the dominant noncovalent interactions in structures 1–3 determining the supramolecular arrays of the gold complexes. In 1 and 2, unusual intermolecular C–H···Au gold–hydrogen co…

Synthesis and characterisation of novel chemical conjugates based on alpha, beta-polyaspartylhydrazide and beta-cyclodextrins

2006

A new family of supramolecular systems based on a synthetic polyaminoacid and cyclic oligosaccharides such as beta-cyclodextrins (beta-CDs) was synthesised. The pharmaceutical potential of these systems arises from the proper combination between the complexing properties of cyclodextrins and the particular pharmacokinetic profile that can be obtained by using macromolecular conjugates with a biocompatible backbone. Five supramolecular conjugates were synthesised by using alpha,beta-polyaspartylhydrazide (PAHy) as a polymeric component and various amounts of two P-CD derivatives. In particular, by reaction of PAHy with beta-CD monoaldehyde, samples named as A(1), A(2) and A(3), bearing, resp…

Nonlocal van der Waals Approach Merged with Double-Hybrid Density Functionals: Toward the Accurate Treatment of Noncovalent Interactions

2015

Noncovalent interactions drive the self-assembly of weakly interacting molecular systems to form supramolecular aggregates, which play a major role in nanotechnology and biochemistry. In this work, we present a thorough assessment of the performance of different double-hybrid density functionals (PBE0-DH-NL, revPBE0-DH-NL, B2PLYP-NL, and TPSS0-DH-NL), as well as their parent hybrid and (meta)GGA functionals, in combination with the most modern version of the nonlocal (NL) van der Waals correction. It is shown that this nonlocal correction can be successfully coupled with double-hybrid density functionals thanks to the short-range attenuation parameter b, which has been optimized against ref…