Search results for "molecular"
showing 10 items of 32340 documents
Biological and Mechanical Characterization of the Random Positioning Machine (RPM) for Microgravity Simulations
2021
The rapid improvement of space technologies is leading to the continuous increase of space missions that will soon bring humans back to the Moon and, in the coming future, toward longer interplanetary missions such as the one to Mars. The idea of living in space is charming and fascinating; however, the space environment is a harsh place to host human life and exposes the crew to many physical challenges. The absence of gravity experienced in space affects many aspects of human biology and can be reproduced in vitro with the help of microgravity simulators. Simulated microgravity (s-μg) is applied in many fields of research, ranging from cell biology to physics, including cancer biology. In…
First observation and study of the K± → π±π0e+e− decay
2018
The NA48/2 experiment at CERN reports the first observation of the K-+/- -> pi(+/-)pi(0)e(+)e(-) decay from an exposure of 1.7 x 10(11) charged kaon decays recorded in 2003-2004. A sample of 4919 candidates with 4.9% background contamination allows the determination of the branching ratio in the full kinematic region, BR(K-+/- -> pi(+/-)pi(0)e(+)e(-)) = (4.24 +/- 0.14) x 10(-6). The study of the kinematic space shows evidence for a structure dependent contribution in agreement with predictions based on chiral perturbation theory. Several P- and CP-violating asymmetries are also evaluated.
Aplicaciones de la citologia oral por raspado (exfoliativa) en el cáncer y precáncer oral
2005
La citología por raspado es un procedimiento simple e incruento que ha sido objeto de controversia sobre su validez real en patología oral. En los últimos tiempos ha resurgido en base a su aplicación en el precáncer y el cáncer oral, tanto como metodología diagnóstica como predictiva y para la monitorización de los pacientes. Se han desarrollado nuevas técnicas sobre aspectos diagnósticos, como la aplicación 'brush biopsy', y múltiples estudios moleculares sobre las células recogidas. En esta revisión analizamos los aspectos más novedosos en relación con las aplicaciones de la citología por raspado o exfoliativa en la patología oral cancerosa y precancerosa, dirigida de un modo especial a l…
Topological canal foliations
2019
Regular canal surfaces of $\mathbb{R}^3$ or $\mathbb{S}^3$ admit foliations by circles: the characteristic circles of the envelope. In order to build a foliation of $\mathbb{S}^3$ with leaves being canal surfaces, one has to relax the condition “canal” a little (“weak canal condition”) in order to accept isolated umbilics. Here, we define a topological condition which generalizes this “weak canal” condition imposed on leaves, and classify the foliations of compact orientable 3-manifolds we can obtain this way.
Proteins in Ionic Liquids: Reactions, Applications, and Futures
2019
Biopolymer processing and handling is greatly facilitated by the use of ionic liquids, given the increased solubility, and in some cases, structural stability imparted to these molecules. Focussing on proteins, we highlight here not just the key drivers behind protein-ionic liquid interactions that facilitate these functionalities, but address relevant current and potential applications of protein-ionic liquid interactions, including areas of future interest.
Clinical assessment and comparison of ACL reconstruction using synthetic graft (Neoligaments versus FiberTape).
2021
Background Due to the low potential for primary biological healing of the anterior cruciate ligament (ACL), the most popular approach is currently reconstruction using a graft. Recent research indicates that the technique of strengthening a damaged ligament with synthetic tapes (internal bracing) may be an alternative to reconstructive treatment, especially in cases of partial ACL damage. Objectives To compare and evaluate the possibility of using a synthetic graft (Neoligaments or FiberTape) to treat partial lesions of the ACL. Material and methods This was a retrospective cohort study. Selected from a pool of 128 patients undergoing primary unilateral intra-articular ACL reconstruction du…
Bioactive Compounds, Nutritional Quality and Antioxidant Capacity of the Red-Fleshed Kirkwood Navel and Ruby Valencia Oranges
2022
Kirkwood Navel and Ruby Valencia are two spontaneous bud-mutations of the ordinary Washington Navel and Valencia late oranges characterized by the red coloration of their flesh. The purpose of this study was to analyze the physiological features, internal fruit quality, contents of relevant bioactive compounds and antioxidant capacity in the pulps of the red-fleshed fruits compared with the ordinary oranges during late development and maturation. In general, the content of sugars, organic acids, vitamin C, tocopherols, total phenolics and flavonoids, the hydrophilic antioxidant capacity and their changes during maturation were similar in the red-fleshed oranges and in the corresponding blon…
The SO2F2 quasi-spherical top: Correspondence between tensorial and Watson's formalisms
2006
Abstract The SO2F2 quasi-spherical top molecule with C2v symmetry is considered as a distorted spherical top deriving from the SO 4 2 − tetrahedral ion. We present here a detailed correspondence between the tensorial formalism using the Td⊃C2v reorientation and the usual Hamiltonian of Watson. We have also performed ab initio calculations in order to determine the centrifugal distorsion constants in the vibrational ground state.
Measurement of Physical Fitness and 24/7 Physical Activity, Standing, Sedentary Behavior, and Time in Bed in Working-Age Finns : Study Protocol for F…
2022
Background: Population studies gathering measured data on fitness and physical behavior, covering physical activity, standing, sedentary behavior, and time in bed, are scarce. This article describes the protocol of the FINFIT 2021 study that measures fitness and physical behavior in a population-based sample of adults and analyzes their associations and dose–response relationships with several health indicators. Methods: The study comprises a stratified random sample of 20–69-year-old men and women (n = 16,500) from seven city-centered regions in Finland. Physical behavior is measured 24/7 by tri-axial accelerometry and analyzed with validated MAD-APE algorithms. Health and fitness examinat…
NF-κB e Id2 como nodos de regulación de redes transcripcionales en diferentes modelos biológicos
2015
En el presente proyecto de tesis se ha contribuido a elucidar el importante papel que ejercen los nodos de regulación transcripcional en un contexto fisiológico en el que tienen lugar diferentes procesos biológicos, moleculares y celulares de forma simultánea y coordinada. Concretamente, se ha estudiado cómo dos inputs primarios, NF-κB e Id2, desencadenan un determinado output o proceso biológico concreto en la glándula mamaria y el hígado. Estudios previos describen un aumento de los niveles de actividad del factor transcripcional NF-κB durante el proceso de la involución de la glándula mamaria tras el ciclo embarazo/lactancia. Los resultados obtenidos demuestran que NF-κB tiene un papel i…