Search results for "molecule"

showing 10 items of 5162 documents

Chemical and Spectroscopical Properties of Medium Sizedtrans- andcis-Bicyclo[n.1.0]alk-2-ynes

1997

Chemical and spectroscopical properties of cis- and trans-cyclopropano-anellated cycloalkynes of medium ring size are investigated and compared with results from force field calculations. IR and 13C-NMR data of the alkynes reflect the deformation of the triple bond due to ring strain. Parallel to bending the reactivity increases with decreasing ring size, the trans fused alkynes prove to be nearly as reactive as the cis fused with a two carbon smaller ring size. The bicycloalkynes are complexed with silver triflate. 13C NMR reveals that the triple bond as well as the cyclopropane serve as ligands.

Bicyclic moleculeChemistryOrganic ChemistryGeneral ChemistryNuclear magnetic resonance spectroscopyCarbon-13 NMRTriple bondRing strainCyclopropaneRing sizeCrystallographychemistry.chemical_compoundPhysical and Theoretical ChemistryTrifluoromethanesulfonateLiebigs Annalen
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Synthetically attractive indolization processes and newer methods for the preparation of selectively substituted indoles

1988

The synthetically interesting processes available for indolization reactions are discussed and illustrated in tabular form and particular emphasis is placed on the more recent methods.

Bicyclic moleculeChemistryOrganic ChemistryOrganic chemistryJournal of Heterocyclic Chemistry
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Arynic species; effect of substituents on the reactivity of monosubstituted dehydrobenzenes

1986

Abstract Evidence is presented demonstrating the existence of free dehydrobenzenes in the thermal decomposition of diaryliodonium-2-carboxylates, and that o-benzyne itself and its 4-methyl-, 4-chloro-,4-bromo- and 4-nitro-derivatives are generated from insoluble polymer-bound precursors and trapped by a second solid phase in Diels-Alder reactions. Lifetimes for these elusive species are determined.

Bicyclic moleculeChemistryOrganic ChemistryThermal decompositionBiochemistryArynechemistry.chemical_compoundComputational chemistryPhase (matter)Drug DiscoveryOrganic chemistryReactivity (chemistry)PhenolsPyrolysisDiels–Alder reactionTetrahedron
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ChemInform Abstract: Stereoselective Synthesis of Polycyclic Thiopyrans.

2012

Reactions of benzothiete (I) with bicyclic alkenes exhibit very high π-side selectivity in the formation of polycyclic thiopyrans.

Bicyclic moleculeChemistryOrganic chemistryStereoselectivityGeneral MedicineSelectivityChemInform
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1H and 13C NMR investigation of the fluxional behavior of η6-(bicyclo[6.1.0]Nona-2,4,6-triene)hexacarbonyldiiron- (FeFe)

1977

Abstract The variable temperature 1 H and 13 C NMR spectra of (C 9 H 10 )Fe 2 (CO) 6 have been recorded. The molecule is fluxional. The high temperature spectra indicate an apparent plane of symmetry bisecting the bound organic ligand, whereas the low temperature limiting spectra are entirely consistent with the asymmetric skew-type structure found in the crystal. Thus the molecule is also properly described in solution as μ-(2-σ,6,7-η:35-η-bicyclo[6.1.0]nonatriene)hexacarbonyldiiron(FeFe). Based on the observed line shape changes of the carbonyl resonances between −140 and −110°C, it is shown that the twitching and not the gliding process is responsible for the relative movement of the F…

Bicyclic moleculeChemistryStereochemistryLigandChemical shiftOrganic ChemistryCarbon-13 NMRRing (chemistry)BiochemistrySpectral lineInorganic ChemistryCrystallographyMaterials ChemistryMoietyMoleculePhysical and Theoretical ChemistryJournal of Organometallic Chemistry
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(8,9-Dihydro-7H-imidazo[1,2-c][1,3]diazepin-5-yl)-cyanamide und homologe imidazo-bizyklen

1984

Die Reaktion der 2-(ω-Aminoalkyl)-imidazole 4a-f mit N-Cyanodiphenyl-imidocarbonat (7) fuhrt zu den entsprechend hydrierten Imidazo[1,5-a]imidazolen, Imidazo[1,2-c][1,3]diazepinen und Imidazo[1,2-c][1,3]diazocinen (9a-f), die im Verhalten gegenuber Nucleophilen und in ihren spektroskopischen Eigenschaften den (7,8-Dihydro-imidazo[1,2-c]pyrimidin-5-yl)-cyanamiden (3) [1] vergleichbar sind. The reaction of the 2-(ω-aminoalkyl)imidazoles 4a-f with N-cyanodi-phenylimidocarbonate (7) leads to appropriately hydrogenated imidazo-[1,5-a]imidazoles, imidazo[1,2-c][1,3]diazepines and imidazo[1,2-c][1,3]diazocines (9a-f), which are similar to (7,8-dihydroimidazo)[1,2-c]pyrimidin-5-yl)cyanamides (3)[1]…

Bicyclic moleculeChemistryStereochemistryOrganic ChemistryNuclear magnetic resonance spectroscopyJournal of Heterocyclic Chemistry
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On the mechanism of catalytic isomerization of xylenes. Molecular orbital studies

1979

Abstract On the basis of CNDO/2 molecular orbital calculations, we postulate the following detailed mechanism for the catalytic isomerization of xylenes which explains the initial product distributions and also our previous finding that the reaction is intramolecular: (i) adsorption of xylene on a surface acid site to form a Wheland-type complex; (ii) disrotatory cyclization of the protonated species into a bicyclo[3, 1, 0]hexenyl complex; (iii) migration of the methylene bridge to a new side of the pentagonal ring; (iv) change of the new bicyclic species back into the corresponding Wheland-type complex; (v) desorption of the xylene isomer from the surface of the catalyst. The overall rate …

Bicyclic moleculeChemistryXyleneProtonationRate-determining stepPhotochemistryMedicinal chemistryCatalysisCNDO/2chemistry.chemical_compoundMolecular orbitalPhysical and Theoretical ChemistryConrotatory and disrotatoryIsomerizationJournal of Catalysis
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ChemInform Abstract: An Easy Access to Fused Chromanones via Rhodium Catalyzed Oxidative Coupling of Salicylaldehydes with Heterobicyclic Olefins.

2016

Diazabicyclic and urea-derived bicyclic olefins react with salicylaldehydes to produce various types of fused chromanone systems of biological interest in a single step (mechanism).

Bicyclic moleculeChemistrychemistry.chemical_elementOxidative coupling of methaneSingle stepGeneral MedicineCombinatorial chemistryCatalysisRhodiumChemInform
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How far the substituent effects in disubstituted cyclohexa-1,3-diene derivatives differ from those in bicyclo[2.2.2]octane and benzene?

2018

Substituents effects in cyclic diene derivatives are studied using quantum chemical modeling and compared to the corresponding effects in aromatic (benzene) and fully saturated (bicyclo[2.2.2]octane) compounds. In particular, electronic properties of the fixed group Y in a series of 3- and 4-X-substituted cyclohexa-1,3-diene-Y derivatives (where Y = NO2, COOH, COO− OH, O−, NH2, and X = NMe2, NH2, OH, OMe, Me, H, F, Cl, CF3, CN, CHO, COMe, CONH2, COOH, NO2, NO) are examined using the B3LYP/6-311++G(d,p) method. For this purpose, quantum chemistry models of the substituent effect: cSAR (charge of the substituent active region) and SESE (substituent effect stabilization energy) as well as trad…

Bicyclic moleculeDienesubstituent effects010405 organic chemistrymolecular modelingSubstituent010402 general chemistryCondensed Matter PhysicsResonance (chemistry)electronic structure01 natural sciencesQuantum chemistryMedicinal chemistry0104 chemical scienceschemistry.chemical_compoundchemistrysubstituent effect stabilization energyMoietyPhysical and Theoretical ChemistryBenzenecharge of the substituent active regionOctaneStructural Chemistry
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Synthesis and Redox Behaviour of the Chalcogenocarbonyl Dianions, [(E)C(PPh2S)2]2−: Formation and Structures of Chalcogen−Chalcogen Bonded Dimers and…

2010

The lithium salts of the chalcogenocarbonyl dianions [(E)C(PPh(2)S)(2)](2-) (E=S (4 b), Se (4 c)) were produced through the reactions between Li(2)[C(PPh(2)S)(2)] and elemental chalcogens in the presence of tetramethylethylenediamine (TMEDA). The solid-state structure of {[Li(TMEDA)](2)[(Se)C(PPh(2)S)(2)]}-[{Li(TMEDA)}(2)4 c]-was shown to be bicyclic with the Li(+) cations bis-S,Se-chelated by the dianionic ligand. One-electron oxidation of the dianions 4 b and 4 c with iodine afforded the diamagnetic complexes {[Li(TMEDA)](2)[(SPh(2)P)(2)CEEC(PPh(2)S)(2)]} ([Li(TMEDA)](2)7 b (E=S), [Li(TMEDA)](2)7 c (E=Se)), which are formally dimers of the radical anions [(E)C(PPh(2)S)(2)](-) (.) (E=S (5 …

Bicyclic moleculeLigandStereochemistryOrganic ChemistryProtonationGeneral ChemistryTetramethylethylenediamineCrystal structureCatalysisAdductchemistry.chemical_compoundCrystallographyChalcogenchemistrychalcogenocarbonyl dianionskalkogeenikarbonyylidianionitSelone
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